Melanoma Specific Articles & Analysis
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T-knife has used its proprietary HuTCR platform to discover multiple naturally optimized high-affinity TCRs specific for the cancer-testis antigen MAGE-A1. These MAGE-A1-specific TCRs were isolated from the HuTCR platform and in vitro and in vivo activity were compared to different human-derived MAGE-A1-specific TCRs. ...
” Poster Presentation Details Title: Optimal-affinity MAGE-A1-specific T cell receptors (TCRs) generated using the humanized TCR-transgenic mouse platform HuTCR are superior to human donor-derived TCRs Abstract ID: 225 Date: Friday, Nov. 12, 2021 Time: 7:00 am – 5:00 pm Title: MAGE-A1 protein expression pattern in > 5,000 tumor and healthy tissue samples: ...