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Metastasis Articles & Analysis

26 news found

Advanced Tumor Organoid & CAF Co-culture Service to Accelerate Cancer Research

Advanced Tumor Organoid & CAF Co-culture Service to Accelerate Cancer Research

CD Bioparticles, a leading manufacturer and supplier of numerous drug delivery products and services, has announced the launch of its new Tumor Organoid & CAF Co-culture services to provide researchers with a more physiologically relevant in vitro tumor model, enabling a deeper understanding of tumor-stromal interactions and the development of more effective cancer therapies. Although cancer ...

ByCD Bioparticles


Creative Proteomics Cytokine Boosts Cancer Research with Cancer Cytokines Assay

Creative Proteomics Cytokine Boosts Cancer Research with Cancer Cytokines Assay

Cytokine, a subdivision of Creative Proteomics, specializes in providing cytokine research and analytical services for researchers in the pharmaceutical and biotechnology industries, as well as academic institutes and government agencies. Recently, the product manager of the company was pleased to announce the launch of its Cancer Cytokines Assay, assisting in the detection of multiple cytokine ...

ByCreative Proteomics


Surgnova in Croatia!

Surgnova in Croatia!

Surgnova was glad to support the FIRST IRE procedures in Croatia with Dophi™ N3000 Electroporation System for patients with liver metastasis! Dophi N3000 Electroporation System is designed for tumor ablation with advanced precision, safety and reliability. Powered by Irreversible Electroporation (IRE) technology, Dophi™ N3000 can ablate tumors in complex anatomical environment. ...

BySurgnova Healthcare Technologies


Recognizing 10 years of philanthropic support for prostate cancer research

Recognizing 10 years of philanthropic support for prostate cancer research

Two powerhouse researchers in prostate cancer will change the way we treat the disease, thanks to funding from legendary volunteer fundraisers, the Bird Dogs and the Alberta Cancer Foundation. Working with the Alberta Cancer Foundation and the University of Alberta, the Bird Dogs have enabled a new one-term, five-year chair position to further prostate cancer research — the Bird Dogs ...

ByNanostics Inc.


The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils, Halts Cancer Progression and Metastasis

The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils, Halts Cancer Progression and Metastasis

Researchers in the laboratory of Yulia Nefedova, M.D., Ph.D., at The Wistar Institute and collaborators at the Jubilant Therapeutics Inc. have uncovered a novel mechanism by which protein arginine deiminase 4 (PAD4) in neutrophils promotes cancer progression. The paper also found that inhibition of this function of PAD4 reduces primary tumor growth and metastasis and enhances checkpoint inhibitor ...

ByJubilant Therapeutics Inc.


Jubilant Therapeutics Inc. announces US FDA clearance of IND for JBI-778, an Oral, Brain Penetrant and Selective PRMT5 Inhibitor, for treatment of solid tumors with brain metastases and primary brain tumors

Jubilant Therapeutics Inc. announces US FDA clearance of IND for JBI-778, an Oral, Brain Penetrant and Selective PRMT5 Inhibitor, for treatment of solid tumors with brain metastases and primary brain tumors

Jubilant Therapeutics Inc., a biopharmaceutical Company advancing small molecule precision therapeutics to address unmet medical needs in oncology and autoimmune diseases, today announced U.S. Food and Drug Administration (US FDA) clearance of the Investigational New Drug application (IND) for JBI-778, an oral, brain penetrant and selective protein arginine methyl transferase 5 (PRMT5) inhibitor, ...

ByJubilant Therapeutics Inc.


FAPI featured in accolades at annual Society of Nuclear Medicine and Molecular Imaging (SNMMI) meeting

FAPI featured in accolades at annual Society of Nuclear Medicine and Molecular Imaging (SNMMI) meeting

Congratulations to investigators at Hannover School of Medicine and Heidelberg University Hospital for receiving the 2022 SNMMI Image of the Year Award and JNM Editors’ Choice Award for Overall Best Article in 2021, respectively. Both use FAPI as the primary indicator and further underscore its potential impact as a novel radiopharmaceutical. Each year, SNMMI chooses an image that best ...

BySOFIE


Onconova Therapeutics Announces Abstract At The ASCO Annual Meeting Highlighting Narazaciclib’s Differentiated Inhibitory And Improved Safety Profile In Preclinical Models

Onconova Therapeutics Announces Abstract At The ASCO Annual Meeting Highlighting Narazaciclib’s Differentiated Inhibitory And Improved Safety Profile In Preclinical Models

Onconova Therapeutics, Inc. (NASDAQ: ONTX), a clinical-stage biopharmaceutical company focused on discovering and developing novel products for patients with cancer, today announced the publication of an abstract at the American Society of Clinical Oncology (ASCO) Annual Meeting. Featured in the abstract are preclinical data from in vitro and cell-based assays that demonstrate how ...

ByTraws Pharma


First Clinical Candidate Developed using HUB Organoids® and High Content Screening Targets Cancer Stem Cells in Solid Tumors, Published in Nature Cancer

First Clinical Candidate Developed using HUB Organoids® and High Content Screening Targets Cancer Stem Cells in Solid Tumors, Published in Nature Cancer

Crown Bioscience, a JSR Life Sciences company, and HUB Organoids (HUB) announced today the publication of preclinical data in the journal, Nature Cancer, on a bispecific antibody which prevents the onset of metastasis and slows the growth of primary tumors in experimental models of cancer. The study was the result of work by an international consortium, SuppresSTEM which included Crown ...

ByJSR Life Sciences, LLC


Icecure medical presents Ice3 breast cancer trial interim data, hosts cryoablation symposium & conducts hands-on Prosense Training Sessions at the European Conference on Interventional Oncology

Icecure medical presents Ice3 breast cancer trial interim data, hosts cryoablation symposium & conducts hands-on Prosense Training Sessions at the European Conference on Interventional Oncology

IceCure Medical Ltd. (NASDAQ: ICCM) (TASE: ICCM) (“IceCure” or the “Company”), developer of minimally-invasive cryoablation technology, the ProSense System, that destroys tumors by freezing as an alternative to surgical tumor removal, today announced it hosted three key ProSense System events at the European Conference on Interventional Oncology (ECIO) from April 24 to 27, ...

ByIceCure Medical Ltd


Biocartis Announces Presentation of First Prospective Validation Study Data of Merlin Test by Partner SkylineDx at EADO 2022 Conference

Biocartis Announces Presentation of First Prospective Validation Study Data of Merlin Test by Partner SkylineDx at EADO 2022 Conference

Biocartis Group NV (the ‘Company’ or ‘Biocartis’), an innovative molecular diagnostics company (Euronext Brussels: BCART), today announced that its partner SkylineDx will present new data showing that its Merlin Test was able to prospectively reduce more than 37% of surgeries in a noninterventional study for newly diagnosed melanoma patients1 . The abstract publication ...

ByBiocartis NV


In-depth Mitochondrial Function Testing Services at Creative Biogene

In-depth Mitochondrial Function Testing Services at Creative Biogene

New York, United States—April 21, 2022—Defects in mitochondrial function have long been suspected of contributing to the development of cancer. In this regard, Creative Biogene strives to explore mitochondrial functions that are yet to be discovered as well as the pathogenesis of mitochondria-associated cancers and possible interventions through in-depth mitochondrial function testing ...

ByCreative Biogene-Mitochondrial Research


Jubilant Therapeutics Inc. reports isoform-selective PAD4 inhibitors demonstrating high In Vitro selectivity and potency and In Vivo oral bioavailability and anti-tumor activity

Jubilant Therapeutics Inc. reports isoform-selective PAD4 inhibitors demonstrating high In Vitro selectivity and potency and In Vivo oral bioavailability and anti-tumor activity

PAD4 inhibition a novel pathway to inhibit tumor metastasis and tumor growth Data presented at the American Association of Cancer Research Annual Meeting 2022 Jubilant Therapeutics Inc. a biopharmaceutical company advancing small molecule precision therapeutics to address unmet medical needs in oncology and autoimmune diseases, today announced data to be presented at the American ...

ByJubilant Therapeutics Inc.


Context Therapeutics® Announces Acceptance of Five Abstracts to be Presented at the American Association for Cancer Research (AACR) Annual Meeting 2022

Context Therapeutics® Announces Acceptance of Five Abstracts to be Presented at the American Association for Cancer Research (AACR) Annual Meeting 2022

PHILADELPHIA, March 08, 2022 (GLOBE NEWSWIRE) -- Context Therapeutics Inc. (“Context” or the “Company”) (Nasdaq: CNTX), a women’s oncology company developing small molecule and immunotherapy treatments for breast and gynecological cancers, today announced that five abstracts have been selected for poster or symposium presentations at the American Association for ...

ByContext Therapeutics Inc.


RTsafe’s core role for the development of German guidelines for a standard, safe and efficient implementation of Single-Isocentric Multi-Focal SRS throughout the country

RTsafe’s core role for the development of German guidelines for a standard, safe and efficient implementation of Single-Isocentric Multi-Focal SRS throughout the country

RTsafe is happy to announce that its PRIME and Pseudopatient 3D phantoms, have been selected by a consortium of high-end German Radiotherapy Institutions – led by the Division of Medical Physics of the Department of Radiation Oncology at the Medical Center of University of Freiburg – towards supporting a study whose results will be used for the development of national guidelines in ...

ByRTsafe


Classification and Biological Functions of Glycoproteins

Classification and Biological Functions of Glycoproteins

Glycoprotein is a protein containing oligosaccharide chains that are covalently linked to each other. The oligosaccharide chains are usually linked to the protein by glycosylation. Glycoproteins are commonly found in animals, plants and microorganisms, with a wide variety of species and functions. They can be classified into three categories: 1. Soluble glycoproteins, which exist in ...

ByCreative Proteomics


myCare-023 Finds Cellworks Personalized Biosimulation a Stronger Predictor of Therapy Response for AML Patients than Physician Prescribed Treatment

myCare-023 Finds Cellworks Personalized Biosimulation a Stronger Predictor of Therapy Response for AML Patients than Physician Prescribed Treatment

CellworksGroup, Inc., a world leader in Personalized Medicine in the key therapeutic areas of Oncology and Immunology, today announced results from the myCare-023 clinical trial, which found that the Cellworks Biosimulation Platform with its Therapy Response Index (TRI) reliably predicts complete response (CR) and overall survival (OS) for individual Acute Myeloid Leukemia (AML) patients beyond ...

ByCellworks Research India Private Limited


Alpha-1 Biologics Announces Positive Data Published in frontiers in Oncology on Alphataxin in Combination with Anti-PD-1 Therapy that Suppressed Murine Renal Cancer and Metastasis

Alpha-1 Biologics Announces Positive Data Published in frontiers in Oncology on Alphataxin in Combination with Anti-PD-1 Therapy that Suppressed Murine Renal Cancer and Metastasis

Alpha-1 Biologics, a biotherapeutics company developing innovative treatments for cancers and immune deficiencies, today announced that positive data was published in frontiers in Oncology demonstrating Alphataxin, a small molecule that elevates circulating and tumor-infiltrating CD4+ T cells, suppressed kidney cancer and suppressed metastasis in mice. Orally available Alphataxin, is the first ...

ByALPHA-1 BIOLOGICS LLC


Journal Publication: CHI3L1 regulates PD-L1 and anti–CHI3L1–PD-1 antibody elicits synergistic antitumor responses.

Journal Publication: CHI3L1 regulates PD-L1 and anti–CHI3L1–PD-1 antibody elicits synergistic antitumor responses.

“Master Pathway” Discovery. Congratulations to our Founder and Scientific Advisory Board Chairman, Dr. Jack A. Elias, on the publication of his breakthrough lung cancer research in the Journal of Clinical Investigation. Referring to the important role played by CHI3L1 in lung cancer metastasis in the accompanying authors note, Dr. Elias says, “We believe we have discovered a ...

ByOcean Biomedical


Lightpoint Medical to Present Positive Clinical Trial Data for SENSEI Miniature Gamma Probe in Prostate Cancer Surgery

Lightpoint Medical to Present Positive Clinical Trial Data for SENSEI Miniature Gamma Probe in Prostate Cancer Surgery

Lightpoint Medical, a leading medical device company developing and marketing innovative technologies for intra-operative cancer detection, announced clinical trial results today to support the use of the company's miniature surgical gamma probe, SENSEI®, in prostate sentinel lymph node detection. The interim results from the multi-center clinical trial, which involves cancer centers at ...

ByLightpoint Medical, Ltd

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