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Pre Clinical And Clinical Drug Development Articles & Analysis

17 news found

Ace Therapeutics Releases BBBporterâ„¢ Technology Platform to Overcome the Challenges of Brain Drug Delivery

Ace Therapeutics Releases BBBporterâ„¢ Technology Platform to Overcome the Challenges of Brain Drug Delivery

Ace Therapeutics, a biotechnology company pioneering novel central nervous system (CNS) delivery solutions, today announced the release of its BBBporter™ technology platform. This innovative platform is specifically designed to overcome the primary challenge in treating brain diseases: the blood-brain barrier (BBB). By leveraging a suite of biomimetic and AI-powered technologies, ...

ByAce Therapeutics


Validating The BLEO-Induced Mouse Model For Drug Discovery

Validating The BLEO-Induced Mouse Model For Drug Discovery

Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...

BySCIREQ - an emka TECHNOLOGIES Company


Ace Therapeutics Unveils Model Development Services to Power Up Psychiatric Drug R&D

Ace Therapeutics Unveils Model Development Services to Power Up Psychiatric Drug R&D

Ace Therapeutics, a preclinical contract research organization (CRO) actively engaged in mental illness research, has announced the launch of its model development services, which aim to revolutionize psychiatric drug research and development. Psychiatric drug development is a crucial aspect of mental health treatment, as it involves the development of medications that can effectively treat ...

ByAce Therapeutics


Alfa Chemistry Leads the Way in Tailored Preclinical Drug Research Solutions

Alfa Chemistry Leads the Way in Tailored Preclinical Drug Research Solutions

Alfa Chemistry serves as an emerging pharmaceutical research organization with a mission to revolutionize the field of preclinical drug research with its wide range of comprehensive services. With a commitment to quality and excellence, Alfa Chemistry offers pharmacological analysis, drug safety evaluation, pharmacokinetic analysis, and bioanalytical services to streamline the drug development ...

ByAlfa Chemistry


Six Signs your Clinical Development Leadership is Failing

Six Signs your Clinical Development Leadership is Failing

Efficient leadership plays a huge role in bringing a clinical trial to fruition. Pharmaceutical companies are not immune to making mistakes and facing failures. Lack of funding, safety issues, and patient dropouts are some of the struggles clinical development teams face. Some problems you as a leader may face may not always be in your control, e.g., lack of funding. Other ...

ByBrio Group


VeriSIM Life Secures a Federal Grant to Create a Drug Combinatorial Platform Against COVID-19

VeriSIM Life Secures a Federal Grant to Create a Drug Combinatorial Platform Against COVID-19

VeriSIM Life has been awarded a National Science Foundation (NSF) Small Business Innovation Research (SBIR) grant for $255,908 to conduct research and development (R&D) work on rapid repurposing and translation of approved and investigational drugs for COVID-19 using its patented artificial intelligence (AI) driven biosimulation platform, BIOiSIM. VeriSIM Life has developed a whole-body ...

ByVeriSIM Life


Cell Apoptosis Kits at Creative Biogene: Efficient and Convenient

Cell Apoptosis Kits at Creative Biogene: Efficient and Convenient

Creative Biogene unveiled a rich portfolio of efficient cell apoptosis assay kits targeted to detect mitochondrial permeability transition pore (MPTP) as well as mitochondrial membrane potential (MMP) to assist researchers in mitochondrial studies. Mitochondrial dysfunction has been linked to a variety of market therapeutics and pathological diseases. Therefore, studying or maintaining ...

ByCreative Biogene-Mitochondrial Research


GeneCentric Publishes New Data Comparing Predictive Immune Response Profiles in Patients Treated with Checkpoint Inhibition or IL-2

GeneCentric Publishes New Data Comparing Predictive Immune Response Profiles in Patients Treated with Checkpoint Inhibition or IL-2

A novel RNA-based IL-2 treatment response classifier was developed as part of the study in patients with renal cell carcinoma Durham, NC, August 23, 2022 – GeneCentric Therapeutics, a company making precision medicine more precise through RNA-based diagnostics, announced its new publication in Cancer Research Communications that compares the immunogenomic response profiles to anti-PD-(L)1 ...

ByGeneCentric Therapeutics, Inc.


GeneCentric to Present Initial Clinicogenomic Results from the GARNER High-Risk Non-Muscle Invasive Bladder Cancer Real-World Study

GeneCentric to Present Initial Clinicogenomic Results from the GARNER High-Risk Non-Muscle Invasive Bladder Cancer Real-World Study

Durham, NC, May 10, 2022 – GeneCentric Therapeutics, a company making precision medicine more precise through RNA-based diagnostics, announced today an upcoming presentation of initial results from the GARNER (Genomic Analysis of high-Risk Non-muscle invasive bladder cancer) real-world study at the 2022 American Urological Association (AUA) Annual Meeting, which is being held in New ...

ByGeneCentric Therapeutics, Inc.


Fc Fusion Protein Production Service Now Available at Profacgen

Fc Fusion Protein Production Service Now Available at Profacgen

Profacgen, a state-of-the-art protein service provider located in the USA, provides comprehensive one-stop services for pre-clinical drug development, aiming to evaluate and improve the efficacy and safety of new drug candidates. ...

ByProfacgen


GeneCentric to Present Discovery and Initial Clinical Utility of a Novel RNA-Based Gene Signature That Predicts Treatment Response in Patients with Head and Neck Cancer

GeneCentric to Present Discovery and Initial Clinical Utility of a Novel RNA-Based Gene Signature That Predicts Treatment Response in Patients with Head and Neck Cancer

DURHAM, N.C.–(BUSINESS WIRE)– GeneCentric Therapeutics, a company making precision medicine more precise through RNA-based diagnostics, announced today the upcoming oral presentation of the discovery and initial clinical utility of a novel signature that identifies patients with head and neck squamous cell carcinoma (HNSCC) that may benefit from treatment beyond typical surgical ...

ByGeneCentric Therapeutics, Inc.


GeneCentric Therapeutics Identifies RNA-Based Genomic Markers of Clinical Response in Lung Cancer

GeneCentric Therapeutics Identifies RNA-Based Genomic Markers of Clinical Response in Lung Cancer

The Piedmont Study, a Real-World Data Analysis in Patients Treated with Platinum Doublet Chemotherapy and/or Pembrolizumab, Identifies Predictive Biomarkers for Approved First-Line Treatments in NSCLC DURHAM, N.C.–(BUSINESS WIRE)– GeneCentric Therapeutics, a company making precision medicine more precise through RNA-based diagnostics, announced today the completion of its Piedmont ...

ByGeneCentric Therapeutics, Inc.


GeneCentric Therapeutics Closes $7.5 Million Series B1 Financing

GeneCentric Therapeutics Closes $7.5 Million Series B1 Financing

Durham, N.C., Nov. 8, 2021 – GeneCentric Therapeutics, a company making precision medicine more precise through RNA-based diagnostics, today announced the closing of an oversubscribed Series B1 financing, which raised $7.5 million. Proceeds will be used to commercialize GeneCentric’s gene signatures and accelerate the growth of its pipeline of predictive response signatures for ...

ByGeneCentric Therapeutics, Inc.


Thermo Fisher Scientific Showcases Investment and Innovation During CPhI Worldwide 2021

Thermo Fisher Scientific Showcases Investment and Innovation During CPhI Worldwide 2021

Louis, Mo. with 58,000 square feet of manufacturing and production support at the 5KL processing scale and continued support at the 2KL processing scale. To accelerate preclinical development for biologic drug developers, Thermo Fisher recently introduced its enhanced Quick to Clinic solution, designed to help biopharma ...

ByThermo Fisher Scientific


GeneCentric Therapeutics Collaborates with Labcorp to Develop Novel RNA-Based Oncology Diagnostics

GeneCentric Therapeutics Collaborates with Labcorp to Develop Novel RNA-Based Oncology Diagnostics

DURHAM, N.C. – October 12, 2021 — GeneCentric Therapeutics, a company making precision medicine more precise through RNA-based diagnostics, today announced a new strategic collaboration with Labcorp, a leading global life sciences company, to develop and commercialize new RNA-based gene signatures as diagnostics for people with cancer. This latest collaboration builds on the ...

ByGeneCentric Therapeutics, Inc.


Thermo Fisher Scientific To Showcase Investments and Innovation at DCAT Week 2021

Thermo Fisher Scientific To Showcase Investments and Innovation at DCAT Week 2021

This week, Thermo Fisher Scientific will highlight its investments and innovations over the past 12 months across its global pharma services network, which have been focused on areas of accelerated demand including cell and gene therapy, drug product development, biologics manufacturing and clinical supply chain services. These highlights will be showcased this week at Virtual DCAT Week. "This ...

ByThermo Fisher Scientific, LIMS & Laboratory Software


Atomwise Partners with Global Research Teams to Pursue Broad-Spectrum Treatments Against COVID-19 and Future Coronavirus Outbreaks

Atomwise Partners with Global Research Teams to Pursue Broad-Spectrum Treatments Against COVID-19 and Future Coronavirus Outbreaks

Atomwise, the leader in using artificial intelligence (AI) for small molecule drug discovery, announced today it has fifteen research collaborations underway with leading global universities to explore broad-spectrum therapies for COVID-19 and other coronaviruses. Coronaviruses are RNA viruses and include the causative SARS-CoV-2 strain of the current COVID-19 global pandemic as well as MERS ...

ByAtomwise Inc.

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