Stem Cell Differentiation Articles & Analysis
27 news found
Creative Biostructure's expanded catalog now features exosomes isolated from a variety of stem cell sources, including: l Mesenchymal Stem Cells (MSCs): Known for their ability to differentiate into multiple cell types, MSC-derived exosomes are instrumental in tissue repair and immune ...
Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) are major global health threats. Their interaction worsens disease severity, as HIV reduces CD4+ T cells, making individuals more vulnerable to TB. Despite progress, an effective animal model that mimics human immune response during HIV/TB co-infection has been lacking, hindering treatment and vaccine development. Bohorguez et al. ...
Of significant note are the chemical modifications 5mC (5-methylcytosine) and 5hmC (5-hydroxymethylcytosine), which play pivotal roles in the regulation of gene expression and cellular differentiation. A comprehensive understanding of the distribution and dynamic changes in 5mC and 5hmC is of paramount importance when unraveling processes such as tumorigenesis, neurodevelopment, ...
BRM421 is a first-in-class, innovative drug based on a neurotrophic stem cell regenerative peptide (PDSP). It stimulates stem cell differentiation, repairs the cornea, inhibits inflammation, and promotes recovery in DED. ...
BRM421 is derived from BRIM’s proprietary, stem cell regenerative PEDF-derived Short Peptides (PDSPs), which can also be applied across multiple therapy areas and indications. In the treatment of DED, PDSPs are known to activate the proliferation and differentiation of limbal stem cells which leads to rapid ...
BRM421 is a novel, first-in-class regenerative peptide therapy which, if successful, could offer patients complete relief from dry eye symptoms by stimulating the proliferation and differentiation of stem cells to repair damage to the cornea. BRM421 was developed using BRIM’s proprietary stem cell ...
Umoja Biopharma, Inc., an immuno-oncology company pioneering off-the-shelf, integrated therapeutics that reprogram immune cells to treat patients with solid and hematologic malignancies, and TreeFrog Therapeutics, a biotechnology company aimed at making safer, more efficient and more affordable cell therapies based on induced pluripotent stem ...
Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced three abstracts, including two oral presentations and one poster, detailing data on type 1 diabetes (T1D) and its Phase 1/2 trial of VX-880, a stem cell-derived, fully differentiated pancreatic islet cell replacement therapy, have been accepted for presentation ...
CIRM grant awarded to accelerate clinical trial of NRTX-1001, a promising regenerative neuronal cell therapy in adults with drug-resistant seizures NRTX-1001 is the first human cell therapy candidate to enter clinical investigation for the treatment of epilepsy Neurona Therapeutics, a clinical-stage biotherapeutics company advancing regenerative ...
The product is comprised of astrocyte cells created from embryonic stem cells, expanded and differentiated using Kadimastem’s proprietary technology. AstroRx® has shown to support the nerve cells in the central nervous system, including the brain and spinal cord. ...
BRM421 is based on BRIM’s proprietary stem cell regenerative Pigment Epithelium-Derived Factor (PEDF) derived Short Peptide (PDSP) technology platform, which underpins several products in its pipeline and has the potential to be effective in multiple therapy areas and indications. The functional domain of PEDF chosen to generate PDSPs can be used to treat ...
Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today provided updates on its Phase 1/2 clinical trial of VX-880, an investigational stem cell-derived, fully differentiated pancreatic islet cell replacement therapy for people with type 1 diabetes (T1D) with impaired hypoglycemic awareness and severe hypoglycemia. ...
TreeFrog Therapeutics, a biotechnology company aimed at making safer, more efficient and more affordable cell therapies based on induced pluripotent stem cells (iPSCs), today announced the launch of The Stem Cell SpaceShot Grant, a $100,000 research funding in the field of stem ...
Melissa Carpenter, PhD, Chief Scientific Officer, ElevateBio, Regenerative Medicine Author of over 50 peer-reviewed articles and inventor of 34 issued patents, Melissa Carpenter has been pioneering the field of stem cell-derived cell therapies for the past 25 years. She started her career at CytoTherapeutics (became StemCells, Inc), where she ...
Within these protective micro-environments, stem cells can achieve optimal growth in large-scale bioreactors, and can be differentiated into ready-to-transplant 3D microtissues. ...
Neurona Therapeutics, a clinical-stage biotherapeutics company advancing regenerative cell therapies for the treatment of neurological disorders, announced the presentation of preclinical data from its lead inhibitory neuron cell therapy candidate, NRTX-1001. ...
Now bringing over 70 biophysicists, stem cell biologists and bioproduction engineers, TreeFrog Therapeutics raised $82M over the past 3 years to advance its pipeline of stem cell-based therapies in the field of neurodegeneration, cardio-metabolic disorders, and immuno-oncology. ...
Banik’s extensive experience in process development and clinical manufacturing of stem cell products has been key to the development of Neurona’s manufacturing processes and production of NRTX-1001 clinical lots in the company’s own cGMP facility. ...
Vancouver, BC, Canada - November 30, 2021 - Aspect Biosystems, a biotechnology company pioneering the development of bioprinted cell therapies as medicines of the future, is pleased to announce a research agreement with the University Health Network (UHN). Through this collaboration, Aspect Biosystems will combine its bioprinting technology with UHN’s protocols for ...
NESS ZIONA, ISRAEL, October 12, 2021 – Kadimastem Ltd. (TASE: KDST), a clinical stage cell therapy company developing cell therapy treatments for ALS and diabetes, announced today that the Company held a preliminary meeting with the FDA (INTERACT) on October 7, 2021 regarding IsletRx, the company’s cell therapy product in development ...