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Thrombosis Articles & Analysis

38 news found

Ace Therapeutics Releases Cardiovascular Disease Model Development Services to Power Up Related Preclinical Research

Ace Therapeutics Releases Cardiovascular Disease Model Development Services to Power Up Related Preclinical Research

Ultimately, these diverse models are developed to bridge the gap between laboratory research and clinical application for most cardiovascular diseases such as atherosclerosis, hypertension, thrombosis, heart failure, and cardiovascular infection. Utilizing a range of specialized animal-specific hematology analyzers, biochemical analyzers, small animal PET/MRI imaging systems, ...

ByAce Therapeutics


AngioDynamics Completes Patient Enrollment in APEX-AV Study Assessing AlphaVac F1885 System in Treatment of Pulmonary Embolism

AngioDynamics Completes Patient Enrollment in APEX-AV Study Assessing AlphaVac F1885 System in Treatment of Pulmonary Embolism

Pulmonary embolism (PE) can be a life-threatening condition that affects around 900,000 people in the United States every year.2 In most cases, PE is caused by blood clots in the legs, called deep vein thrombosis, that travel to the lungs.2 Patients with submassive or intermediate-risk PE account for 35% to 55% of hospitalized patients with PE and have a mortality rate of 3 to ...

ByAngioDynamics, Inc.


Bayer receives U.S. FDA Fast Track Designation for asundexian atrial fibrillation program

Bayer receives U.S. FDA Fast Track Designation for asundexian atrial fibrillation program

It is currently being evaluated as a potential once-daily oral Factor XIa (FXIa) inhibitor in thrombosis prevention with the goal to reduce clot formation while leaving the body’s ability to respond to bleeding intact. ...

ByBayer AG


New real world study data on reduced risk of adverse kidney outcomes for Xarelto compared to VKA

New real world study data on reduced risk of adverse kidney outcomes for Xarelto compared to VKA

Xarelto is approved for more venous and arterial thromboembolic (VAT) conditions than any other NOAC: The prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (AF) with one or more risk factors The treatment of pulmonary embolism (PE) in adults The treatment of deep vein thrombosis (DVT) in adults The prevention of recurrent PE ...

ByBayer AG


Revacept protects during carotid artery surgery

Revacept protects during carotid artery surgery

All patients required therapy because of dangerous narrowing of the carotid artery and received the nowadays standard basic therapy with the blood platelet inhibitors acetylsalicylic acid (Aspirin©) and/or clopidogrel to prevent renewed vascular occlusion (thrombosis). The vasoconstrictions were removed surgically or by inserting stents, or they were treated with the best ...

ByadvanceCOR GmbH


Bayer progressing well with transformation of pharma business and raises peak sales potential of key growth drivers to over twelve billion euros

Bayer progressing well with transformation of pharma business and raises peak sales potential of key growth drivers to over twelve billion euros

Strong market uptake of Nubeqa and Kerendia Asundexian projected peak sales of more than five billion euros as treatment option for thrombosis and stroke prevention High-value late-stage development portfolio Positive study outcomes from cell & gene therapy pipeline would provide potential upside Shift of resources enhances commercialization and competitiveness Acquired ...

ByBayer AG


World’s First DVT Clot Removing Procedure In London – YouTube (ITV News)

World’s First DVT Clot Removing Procedure In London – YouTube (ITV News)

It’s been used for the first time – on Jackie Field, from Eltham south east London, and cured her of deep vein thrombosis. ITV’s Rags Martel explains how it works. WORLD'S FIRST DVT CLOT REMOVING PROCEDURE IN LONDON ...

BySurmodics, Inc.


Alfa Chemistry Enriches API Supply by Adding Lenalidomide, Parecoxib Sodium, and Rivaroxaban

Alfa Chemistry Enriches API Supply by Adding Lenalidomide, Parecoxib Sodium, and Rivaroxaban

Rivaroxaban Rivaroxaban, as an antithrombotic drug, is widely used in the treatment and prevention of deep vein thrombosis (DVT) symptoms prior to hip or knee replacement surgery, treatment of venous thromboembolism (VTE) and nonvalvular atrial fibrillation, as well as treatment of DVT and pulmonary embolism (PE). ...

ByAlfa Chemistry


Puzzle Medical to Present at AHA 2022 its First-in-Human Study Results

Puzzle Medical to Present at AHA 2022 its First-in-Human Study Results

The design is expected to enable safe percutaneous implantation, with low risk of bleeding, stroke, and pump thrombosis, while providing sustained symptom relief, reduced re-hospitalizations and improved overall quality of ...

ByPuzzle Medical Devices Inc.


Inari Medical Announces Randomized Controlled Trial Evaluating Clinical Outcomes of the ClotTriever System in Deep Vein Thrombosis

Inari Medical Announces Randomized Controlled Trial Evaluating Clinical Outcomes of the ClotTriever System in Deep Vein Thrombosis

DEFIANCE is a randomized controlled trial (“RCT”) comparing the clinical outcomes of patients with iliofemoral deep vein thrombosis (“DVT”) treated with the ClotTriever System versus anticoagulation only. ...

ByInari Medical


Bayer initiates landmark Phase III study program to investigate oral FXIa inhibitor asundexian

Bayer initiates landmark Phase III study program to investigate oral FXIa inhibitor asundexian

FXIa inhibitors that selectively modulate coagulation through FXIa inhibition could represent a fundamentally new approach to antithrombotic treatment, as they prevent thrombosis yet still allow haemostatic clots that are crucial to repair injury. ...

ByBayer AG


Puzzle Medical to Present at TCT 2022 Its First-in-Human Study Results for the ModulHeart™

Puzzle Medical to Present at TCT 2022 Its First-in-Human Study Results for the ModulHeart™

The design is expected to enable safe percutaneous implantation, with low risk of bleeding, stroke, and pump thrombosis, while providing sustained symptom relief, reduced re-hospitalizations and improved overall quality of life. ...

ByPuzzle Medical Devices Inc.


Puzzle Medical Announces the Successful Completion of its First-in-Human Study with its ModulHeart

Puzzle Medical Announces the Successful Completion of its First-in-Human Study with its ModulHeart

The design is expected to enable safe percutaneous implantation, with low risk of bleeding, stroke, and pump thrombosis, while providing sustained symptom relief, reduced re-hospitalizations and improved overall quality of life. ...

ByPuzzle Medical Devices Inc.


Rivaroxaban (Xarelto) approved in Japan for patients with peripheral artery disease (PAD) after revascularisation

Rivaroxaban (Xarelto) approved in Japan for patients with peripheral artery disease (PAD) after revascularisation

Xarelto is approved for more venous and arterial thromboembolic (VAT) conditions than any other NOAC: The prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (AF) with one or more risk factors The treatment of pulmonary embolism (PE) in adults The treatment of deep vein thrombosis (DVT) in adults The prevention of recurrent PE ...

ByBayer AG


Cordis-X Makes Strategic Investment in Adient Medical, Developer of First Fully Absorbable Inferior Vena Cava (IVC) Filter

Cordis-X Makes Strategic Investment in Adient Medical, Developer of First Fully Absorbable Inferior Vena Cava (IVC) Filter

The device is designed to avoid well-documented risks of perforation, migration, fracture, and thrombosis currently associated with IVC filters. Such safety issues have been the focus of the FDA-mandated PRESERVE (Predicting the Safety and Effectiveness of Inferior Vena Cava Filters) Study of IVC filters from six manufacturers. ...

ByAdient Medical, Inc.


Shockwave IVL Coronary Studies Demonstrate Excellent PCI Outcomes in Both Women and Men at One Year

Shockwave IVL Coronary Studies Demonstrate Excellent PCI Outcomes in Both Women and Men at One Year

The components of target lesion revascularization (TLF) were low in both women and men and numerically favored females, including target vessel-myocardial infarction (8.5 percent vs 9.7 percent), target lesion revascularization (2.9 percent vs 4.2 percent) and stent thrombosis (0 percent vs 1.2 percent). “Given the established safety profile of IVL and the high rates of ...

ByShockwave Medical Inc.


ASC Therapeutics Announces Podium and Poster Presentations of IND-Enabling Studies for ASC618, a Second-Generation Gene Therapy for Hemophilia A, at the 25th ASGCT Meeting, May 16-19, 2022 in Washington, D.C.

ASC Therapeutics Announces Podium and Poster Presentations of IND-Enabling Studies for ASC618, a Second-Generation Gene Therapy for Hemophilia A, at the 25th ASGCT Meeting, May 16-19, 2022 in Washington, D.C.

The study design will be presented at the International Society of Thrombosis and Hemostasis (ISTH) Congress in London, U.K in July 2022 and is available at https://www.clinicaltrials.gov/ct2/show/NCT04676048. ...

ByASC Therapeutics


Jubilant Therapeutics Inc. reports isoform-selective PAD4 inhibitors demonstrating high In Vitro selectivity and potency and In Vivo oral bioavailability and anti-tumor activity

Jubilant Therapeutics Inc. reports isoform-selective PAD4 inhibitors demonstrating high In Vitro selectivity and potency and In Vivo oral bioavailability and anti-tumor activity

NETs have been shown to be associated with several pathological processes including, fibrosis, ischemic stroke, preeclampsia, thrombosis, cancers and other autoimmune diseases. Jubliant Therapeutics Inc. is targeting PAD4 inhibition as a novel strategy to treat inflammatory diseases, cancer progression and metastasis. ...

ByJubilant Therapeutics Inc.


Cellphire Therapeutics Appoints Pamela B. Conley to its Board of Directors

Cellphire Therapeutics Appoints Pamela B. Conley to its Board of Directors

Her expertise focuses on therapeutic areas of cardiovascular disease (thrombosis, hemostasis, atherosclerosis, coagulation, hyperlipidemia), inflammation, autoimmune diseases, and hematologic malignancies. She is internationally recognized for her scientific accomplishments (publications, patents, and invited lectures) in the field of thrombosis and ...

ByCellphire Therapeutics, Inc.


Valeo Pharma Obtains Public Reimbursement For Redesca And Redesca Hp In Quebec

Valeo Pharma Obtains Public Reimbursement For Redesca And Redesca Hp In Quebec

LMWHs are injectable anticoagulant drugs used primarily to treat and prevent deep vein thrombosis and pulmonary embolism. Redesca has more than 8 years of proven in-market safety internationally. and more than 150 million patient days treated in Europe alone. ...

ByValeo Pharma Inc.

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