Refine by
Toxicology Articles & Analysis: Older
74 news found
Its expertise spans various preclinical services, including efficacy testing, pharmacokinetics, toxicology, and biomarker development, to support clients in their research and development efforts. ...
Preclinical development Creative Diagnostics provides in vitro biology, in vivo pharmacodynamics, PK/PD, toxicology and formulation development services that enable clients to make decisions about drug candidates, advance the development process and reduce future time and costs. ...
They include efficacy tests, microbial contamination reports and full-service toxicological risk assessment. CD Formulation aids brands in protecting their reputation and fortifying consumer trust. ...
Yang, L., et al (2024) introduces LungVis 1.0, an AI-driven imaging platform integrating light sheet fluorescence microscopy (LSFM) and deep learning for mapping nanoparticle (NP) deposition across murine lungs. The research highlights the advantages of aerosol-based delivery methods over traditional liquid-based approaches, emphasizing the uniformity of NP deposition in distal alveolar ...
Creative Diagnostics, a leading manufacturer and supplier of antibodies, small molecule conjugates and critical assay reagents for food, feed, environmental and toxicological sample analysis, announces the availability of its high-quality Patulin Test Reagents. ...
By providing scientists with tools that better mimic the complex biological processes that occur in vivo, these products enable more accurate and reliable results in drug discovery, toxicology studies, and regenerative medicine research. “We are excited to bring these cutting-edge 3D cell culture systems to our customers,” said the business development manager at ...
Focus on Pharmacokinetics and Toxicology Understanding a drug's absorption, distribution, metabolism, and excretion (ADME) in animal bodies is crucial for determining appropriate dosages and minimizing adverse effects. ...
Comprehensive Project Services Furthermore, Alfa Chemistry provides one-stop biopharmaceutical R&D outsourcing services that encompass the entirety of drug research, encompassing different disciplines such as hemistry, biology, pharmacodynamic evaluation, pharmacokinetic evaluation, and toxicological evaluation. These services include ADC preclinical development, biological ...
In most cases, bioactive molecules exhibit therapeutic, preventing, toxicological and immunostimulating activities. “Bioactive molecules can regulate, modify or modulate a variety of cellular functions including enzymatic activities, signal transduction, gene regulation, and protein function. ...
Schlereth worked for six years as Senior Director Pharmacology and Toxicology at Micromet, and he started in 2000 his career in industry at Bavarian Nordic. In these positions he was responsible for the Discovery, Pharmacology, Toxicology and DMPK (Drug Metabolism & Pharmacokinetics) activities in close collaboration with CMC (chemistry, manufacturing, ...
Commercial and Pipeline Update Product portfolio Acute Care Hospital: RYANODEX®, vasopressin, Barhemsys®, Byfavo® Oncology: BENDEKA, BELRAPZO, PEMFEXY11, TREAKISYM Japan12 75-person commercial team covers all products excluding BENDEKA and TREAKISYM Company projects growth in earnings while still supporting R&D Cash flow from legacy products expected to continue to ...
In preclinical studies, the compound has demonstrated the ability to overcome the “hook effect” that has been observed in some anti-CD73 antibodies. In addition, GLP toxicology studies indicate the compound potentially has a wide therapeutic window. ...
In addition to samuraciclib, Carrick is also developing a novel CDK12/13 inhibitor / Cyclin-K glue-degrader which has advanced into IND enabling toxicology ...
Its PROTAC in vivo evaluation services encompass general studies of toxicology and in vivo pharmacokinetics, tests of allergy and in vitro hemolysis, as well as immunotoxicology analysis. ...
In preclinical studies, the compound has demonstrated the ability to overcome the “hook effect” that has been observed in some anti-CD73 antibodies. In addition, GLP toxicology studies indicate the compound potentially has a wide therapeutic window. ...
In silico modelling for CYP in preclinical species can also reduce animal testing in toxicology studies, making trials quicker, less expensive, and more ethical. ...
These findings suggest that PMC-309 can offer a new treatment strategy in immuno-oncology area as it can be used in combination with other drugs to improve their low-response rates. The GLP-Toxicology studies are already completed, and no serious safety issues were observed. ...
The Funding Supports Development of an Intramuscular ENA-001 From Pre-Clinical Toxicology Through Filing for Approval in the United States Enalare Therapeutics Inc., a clinical stage biopharmaceutical company dedicated to developing novel compounds for the treatment of life-threatening critical care diseases and community medical threats, announced today that it has received a ...
Furthermore, ATG-101 has also shown an excellent safety profile in Good Laboratory Practice (GLP) toxicology studies. ATG-101 is the first PD-L1/4-1BB bispecific antibody entering clinical development in Australia and is currently being evaluated in clinical studies in Australia, China, and the U.S. ...
A deep and thorough understanding of drug products is required, including different parameters such as the toxicology, pharmacokinetics, and physicochemical properties of drug chemicals,” said the Marketing Chief of CD Formulation. ...