Ubiquitinated Protein Articles & Analysis
5 news found
Proteolysis-targeting chimera (PROTAC) is a revolution in protein degradation. PROTACs take over the ubiquitin-proteasome system to degrade pathogenic proteins. They’re complex molecules made up of an E3 ligase ligand, a protein-binding ligand (also called the warhead), and a linker that links those two functional ...
Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein. J Biol Chem. 2012;287(41):34091-34100. ...
The updated services provide scientists with comprehensive advanced platform for their projects. The ubiquitin proteasome system relies heavily on E3 ligases (UPS). As a major modulator of protein homeostasis, UPS is essential in signal transduction, mitophagy, DNA damage repair, inflammatory pathways, endocytosis, and cell cycle progression. ...
Ubiquitin modification induces protein degradation, which affects the function, localization, and activity of proteins. ...
The company has recently announced Protein Drug Modification Analysis service to help researchers determine the modification type, modification site, and modification structure of protein drugs. ...