Vaginal Opening Articles & Analysis
2 news found
The study was conducted at the BioVirtus Research Site, Józefów, Poland and enrolled 30 healthy volunteers. Stage 1 was an open-label single-dose vaginal or rectal application of the OB-002H gel in 12 participants. Stage 2 was a multiple-dose vaginal application, with an initial open-label application of OB-002H gel ...
OB-002, a highly potent chemokine analog of CCL5 (a ligand for the CCR5 HIV co-receptor), has previously been shown to be completely protective in a non-human primate model of vaginal HIV transmission (Veazey R et al. JID 2009). The Phase 1 study design included open-label single-dose (vaginal and rectal) and multi-dose product ...