Endocrine Effect Articles & Analysis
6 news found
ESR1 mutations are present in up to 40% of ER+, HER2- advanced or metastatic breast cancers. ESR1 mutations are a known driver of resistance to standard endocrine therapy, and so far, have been difficult to treat. ORSERDU is the first endocrine innovation in more than 20 years, specifically addressing ESR1 mutations, a major unmet need. The Menarini Group (“Menarini”), a ...
Prelude Corporation (PreludeDx, a leader in molecular diagnostics and precision medicine for early-stage breast cancer, announced compelling results in 926 women diagnosed with ductal carcinoma in situ (DCIS). The new information was presented in an oral abstract session at the American Society of Clinical Oncology (ASCO) Annual Meeting at McCormick Place, Chicago, IL. The results of the study ...
Endocrine effects and altered reproductive and developmental parameters were observed in both male and female rats, when exposed at a dose level that has been considered safe for humans. The findings of the study, which takes into account exposure from the in utero stage and all throughout adulthood, are particularly relevant considering how widely people are exposed to ...
EPA is proposing to use ground-breaking tools developed in the ToxCast program to improve testing for chemicals that have the potential to disrupt hormone function in the human body. EPA uses automated chemical screening technologies to rapidly and simultaneously perform tests on thousands of chemicals and feed the results into computational models to predict hormone-related, endocrine activity. ...
The US Environmental Protection Agency have come under fire from leading NGOs for its outdated testing program of endocrine-disrupting chemicals. It is feared that the numerous holes in the current programme fail to detect many serious effects on human development. The Environmental Protection Agency is ready to start testing 67 pesticide ingredients for their possible endocrine disruption ...
For days now, a swollen Mississippi River has menacingly roamed far from its banks, devouring large swatches of picturesque river towns and some of the Midwest's best farmlands. While countless news organizations chronicle both the courage of those fighting 'Big Muddy's' assault and the anguish of those wounded by it, another battle is about to begin. This battle will go all but unseen, for the ...