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RaySearch Laboratories
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Adaptive Therapy

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In adaptive therapy planning frequent imaging is used to compensate for anatomical differences that occur during the course of treatment. Re-planning is considered once significant changes are observed. RayStation is specifically designed to make adaptive therapy faster and easier in clinical practice. It includes modules designed for dose tracking, deformable registration, and adaptive re-planning. RaySearch has collaborated with leading cancer centers worldwide to pioneer the use of adaptive planning.
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Use the dose tracking module in RayStation to evaluate the actual delivered dose to the patient. The dedicated module and the fast and diverse tools will enable you to evaluate daily changes as well as evaluating trends as the treatment progresses.

During treatment, fraction images are acquired daily or regularly for patient positioning. When treatment time images of the patient, from CT, PET/CT, cone-beam CT or MR, are acquired - it is possible to use these images to evaluate the daily delivered dose.

When treatment time images of the patient from CT, PET/CT, cone-beam CT, MVCT or MR, are acquired, you can compute dose on the daily images to evaluate the actual delivered dose to the patient. Deform and accumulate doses from different fractions in a common geometry to compute the accumulated delivered dose over the course of treatment.

  • Dose calculation based on CBCT
  • Creation of synthetic CT based on CBCT
  • Easy dose accumulation over fractions
  • Dedicated workspace for evaluating daily doses and deformable dose accumulation
  • Fraction schedule shows delivered fractions, acquired images and available doses
  • Synchronized side-by-side views of planned and delivered dose
Deformable registration in RayStation enables the matching of anatomy over multiple image data sets. The functionality enables fast workflows for fractional image segmentation as well as dose comparisons and accumulations over different images. It allows the delivered dose to be deformed back to the planning CT and accumulated for a comparison with the planned dose up to that fraction.

Deformable registration also allows for fast contouring of the fractional image data sets. Contours from the planning image set, or other fractional image set, can be propagated to the new image using the known deformation.

  • Propagation of ROI contours or meshes between images, including 4D-CT
  • Hybrid intensity and structure based deformation ANACONDA algorithm recommended for adaptive (GPU supported)
  • Biomechanical model based deformation algorithm (MORFEUS based)
  • Tools for analysis and evaluation of deformable registration
Modification of treatment plans can be decided based on the information collected through dose tracking. The adaptive re-planning module provides a wide range of adaptive re-planning tools that consider the accumulated dose and observed deviations of the patient’s geometry. Plans can then be re-optimized and adjusted to compensate for dose coverage problems or to adapt to adjusted clinical goals. Optimization objectives can be set to assure dose levels on future fractions only or to include already delivered dose to meet total dose constraints on organs at risk.

Re-planning options range from simple adaptations, such as adjustments of beam weights, to complete re-planning that involves re-optimization of the intensity modulation.

  • Adaptive re-planning workspace
  • Fraction schedule showing delivered and re-planned fractions
  • Toolbar including relevant parts of plan creation, plan optimization and plan approval