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Retinal Degeneration Equipment & Supplies In Australasia
7 equipment items found
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
HIOC is a potent and selective activator of TrkB (tropomyosin related kinase B) receptor. HIOC can pass the blood-brain and blood-retinal barriers.HIOC activates TrkB/ERK pathway and decreases neuronal cell apoptosis. HIOC attenuates early brain injury after SAH (subarachnoid hemorrhage). HIOC shows protective activity in an animal model for light-induced retinal ...
Manufactured by:Diagnosys LLC based inLowell, MASSACHUSETTS (USA)
The Dark Adaptometry module uses the ColorDome™ or ColorFlash™ stimulator to perform a full or partial field dark adaptation to accurately measure retinal parameters such as cone sensitivity, rod sensitivity and the rod-cone break point. The dark adaptometry test may be run for single or dual eye measurements or a combination. Protocols include the Marmor Test as well as a wide array ...
Manufactured by:PhenoSys GmbH based inBerlin, GERMANY
The optomotor response (OMR) is a reflex used to assess visual function. The PhenoSys qOMR (quantitative optomotor response) is a unique system that automatically measures the OMR with minimal experimenter effort. It uses a virtual stimulation cylinder that continuously aligns with the animal´s head position. Based on real-time head tracking, quantitative OMR measurements run fully ...
Manufactured by:Taconic Biosciences, Inc. based inRensselaer, NEW YORK (USA)
One of the most used inbred mouse models, the C57BL/6 is used in nearly every research application, and it's commonly used as the genetic background for transgenic mouse models. It is also the preferred model for studying diet-induced obesity and the chronic experimental autoimmune encephalomyelitis model of multiple ...
Manufactured by:Konan Medical USA, Inc. based inIrvine, CALIFORNIA (USA)
Checking pupils for an APD is an important part of the comprehensive eye exam, and is recommended in the AAO’s Preferred Practice Patterns for POAG suspects and patients, however the swinging flashlight method is difficult for humans to do well, and even more difficult and time consuming to accurately quantify. Importantly, there is evidence that subtle APDs may be clinically significant. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
N-Nitroso-N-methylurea (NMU;MNU;NMH) is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of ...