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Drug Response Equipment & Supplies In Canada Manitoba
17 equipment items found
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
KRAS mutation is found in several cancers such as pancreatic cancer, colorectal cancer, lung cancer, biliary tract cancer and thyroid cancer. The existence of KRAS mutations is often related with a prognostic marker to drug response. For example, KRAS mutation is considered a strong prognostic marker for drug response of tyrosine ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
NRAS mutation is found in several cancers such as melanoma (13~25%), colorectal cancer (1~6%), lung cancer (1%), thyroid cancer (7%) and hepatocellular carcinoma (10%). It is know that the drug response against colorectal cancer medicine such as Erbitux and Cetuximab decreased and the prognosis of the metastatic colorectal cancer patient is bad if the patient has ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
Usually, it is hard to find lung cancer in the early stage and is diagnosed as lung cancer when it is already progressed. So the prognosis tends to be bad. It is known that the patients with EGFR mutation show very high drug responses against EGFR tyrosine kinase inhibitor (TKI) such as Gefitinib (Iressa, AstraZenca) and Erlotinib (Tarceba, Roche). We expect that ...
Manufactured by:DX Fluidics based inSuzhou, CHINA
They utilize precise microstructures to manipulate and observe cells at a microscopic scale. Applications include drug screening, disease modeling, and tissue engineering. Various types are used in research, such as lung and heart tissue chips, which mimic organ structures and functions, providing insights into physiological and pathological processes. Microfluidic PEEK chips and ...
by:Wondfo USA Co Ltd. based inWillowbrook, ILLINOIS (USA)
While it is used clinically for severe pain, most fentanyl-related overdose cases are linked to its presence in illegal drug markets. In response to this crisis, the SAFEIife- Fentanyl (FTY) Liquid & Powder Drug Test Strip can determine if fentanyl is present in a liquid or powder, providing vital information to help with harm ...
Manufactured by:Lexogen GmbH based inVienna, AUSTRIA
SLAMseq is a high-sensitivity method for time-resolved measurement of newly synthesized and existing RNA in cultured cells. SLAMseq enables resolution of RNA synthesis and degradation kinetics. Lexogen offers a family of kits based on the new SLAMseq method: Thiol (SH)-Linked Alkylation for the Metabolic sequencing of RNA. SLAMseq enables the identification and quantification of newly synthesized ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
In the landmark study, it was demonstrated for the first time that our functional precision-oncology platform can improve patient outcome in a prospective interventional ...
Manufactured by:BTNX Inc. based inPickering, ONTARIO (CANADA)
The Rapid Response Saliva Drug Test is an easy to use, on-site saliva drug test with built-in test strips. This oral fluid test is a rapid, qualitative screening test that simultaneously detects Marijuana (THC), at the cut-off level of 30 ng/mL, and/or Cotinine (COT), at the cut-off level of 40 ng/mL, in human oral fluid. This multi panel ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Angiogenesis, the sprouting of new blood vessels from pre-existing vasculature, plays an important role in the maintenance of body homeostasis and the progression of cancer and Alzheimer’s disease, among others. Studying vessel formation can help identify and validate targets and candidates for treatment of a variety of diseases. Using Ncardia’s human iPSC-derived endothelial cells, ...
Manufactured by:Cytocast based inBudapest, HUNGARY
The CYTOCAST DIGITAL TWIN Platform represents a cutting-edge advancement in precision medicine, aiming to transform patient care through personalized treatment strategies. By integrating multi-omics data—such as genomic, proteomic, and metabolomic profiles—with detailed clinical information, this platform creates a precise digital replica of each patient's unique biological ...
Manufactured by:Amoy Diagnostics Co., Ltd. based inXiamen, CHINA
Neurotrophic tropomyosin-related kinase (NTRK) is a group of high affinity nerve growth factor (NGF) receptors, including tropomyosin receptor kinases (Trk) A, B, and C which are encoded by NTRK1, NTRK2, and NTRK3 genes, respectively. NTRK proteins, upon NGF ligand binding, function in the phosphorylation of members of the RAS/MAPK, PI3K/AKT, PLC-y pathways that play a key role in cell ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
APD668 is a potent, selective and orally active agonist of G-protein coupled receptor GPR119, with EC50s of 2.7 nM and 33 nM for hGPR119 and rGPR119, respectively. APD668 shows no significant inhibition of any of the five major CYP isoforms with the exception of CYP2C9 (Ki=0.1 μM). APD668 can be used for the research of steatohepatitis and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer ...
Manufactured by:Aidar Health based inBaltimore, MARYLAND (USA)
MouthLab Mobile Monitoring System makes precision medicine a reality by rapidly gathering, and efficiently analyzing a large amount of clinically relevant subjective and objective information in real-time. It's as simple to use as a toothbrush yet comprehensive enough to provide a daily snapshot of your overall health, enabling early detection of disease progression and timely ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell ...
Manufactured by:Cytocast based inBudapest, HUNGARY
Cytocast is at the forefront of medical technology with its innovative Cytocast Digital Twin Platform™, a pioneering solution in drug development and personalized medicine. At its core is the CYTOCAST DIGITAL TWIN Cell™, a highly detailed simulated human cell model encompassing 15 tissue types. The platform integrates multi-omics data and bioinformatics within high-performance ...