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Targetmol In Vitro Method Equipment & Supplies In St Kitts Nevis

1 equipment items found
Available In St. Kitts & NevisNear St. Kitts & Nevis

TargetMol - Model RMC-9805 - Inhibitor

TargetMol - Model RMC-9805 - Inhibitor

Manufactured by:TargetMol Chemicals Inc.   based inWellesley Hills, MASSACHUSETTS (USA)
RMC-9805 is a novel, mutant-selective, covalent and oral KRASG12D (ON) inhibitor. A stable and high affinity triple complex is formed between RMC-9805, KRASG12D, and cyclophilin A, which inhibits signal transduction downstream of KRASG12D (ON) by disrupting its interaction with downstream effectors. RMC-9805 can induce cell apoptosis and promote tumor regression in preclinical KRASG12D tumor ...
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