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Pre Clinical Study Equipment & Supplies In Usa Illinois
244 equipment items found
by:OSSIO Inc based inWoburn, MASSACHUSETTS (USA)
Comprised of OSSIOfiber® Intelligent Bone Regeneration Technology, Fully integrates into native anatomy without adverse inflammation,, as proven in pre-clinical studies, Rivals performance of metal headless cannulated compression screws1, Can be trimmed to desired length ...
Manufactured by:Jointechlabs Inc. based inNorth Barrington, ILLINOIS (USA)
Based on our platform and technology, Jointechlabs is developing therapies for unmet medical needs. Our first therapeutic in clinical development JTL-T-01 is a proprietary injectable stem cell scaffold as a biologic therapy for osteoarthritis, for approval under the FDA’s fast-track program. JTL-T-01 has been designed as an autologous point-of-care therapy enabling the ...
Manufactured by:Wolfmet based inManchester, UNITED KINGDOM
This efficiency, coupled with cost-effectiveness, has made Wolfmet 3D a game-changer in the design and manufacturing of collimators and shielding. Ongoing pre-clinical studies indicate that 3D printed tungsten collimators substantially enhance image quality. Wolfmet 3D's ability to produce standard as well as complex bespoke designs provides ...
by:LIXTE Biotechnology Holdings, Inc. based inPasadena, CALIFORNIA (USA)
Pre-clinical studies showed that LB-100 alone inhibits a spectrum of human cancers but when combined with standard cytotoxic drugs and/or radiation, LB-100 potentiates their effectiveness against hematologic and solid tumor cancers without enhancing toxicity. ...
Manufactured by:AGC Biologics based inBothell, WASHINGTON (USA)
Our ready-to-use platform capabilities are built on cell factories (up to 48L) and bioreactors (up to 200L) using adherent processes, designed entirely in-house. Our quality systems, GMP manufacturing scale and regulatory qualification allow us to meet both clinical and commercial demand. Moreover, our scale down capabilities provide flexible and cost-effective solutions for ...
Manufactured by:Pluristem Therapeutics Inc. based inHaifa, ISRAEL
PLX-Immune are cells that have been induced with tumor necrosis factor alpha (TNF-a) and interferon-gamma (IFN-g), to transiently alter their secretion profile. The product has been evaluated in pre-clinical studies and a peer-reviewed article in the journal Scientific Reports, from Nature, was published which examined the effect of the cells in ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for an investigational gene therapy for Gaucher disease type ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for a gene therapy for Pompe disease. We have shown a favorable preclinical safety and efficacy profile in a mouse model of Pompe ...
Manufactured by:CytomX Therapeutics, Inc. based inSouth San Francisco, CALIFORNIA (USA)
CX-188 is our wholly owned PD-1-targeting Probody therapeutic. As with anti-PD-L1 therapies, PD-1 monotherapy and combinations have been associated with significant toxicities. Our preclinical studies have shown that CX-188 has the potential for an improved therapeutic index relative to PD-1 antibodies. The IND for CX-188 was cleared by the FDA. Following a program and portfolio prioritization, ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for mucopolysaccharidosis type II (MPS II), or Hunter syndrome. The program is being developed in collaboration with Brian Bigger, Ph.D., who has published favorable preclinical data in a mouse model of Hunter ...
Manufactured by:EMulate Therapeutics, Inc. based inBellevue, WASHINGTON (USA)
Indolor Therapeutics is feasibility (phase I) trial ready for the treatment of acute and chronic pain by the application of specific pain-managing ulRFE fields, another expression of EMulate’s Therapeutic ...
Manufactured by:CTIBiotech based inMeyzieu, FRANCE
Using the latest tools in bioengeneering, our researchers are now printing cancer tissues in 3D. These models can be used for highly significant pre-clinical trials and can be produced in 6/48/96 well plates for high throughput ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES004 is a potentially best-in-class antibody targeting pan-allele signal-regulatory protein alpha (SIRPα). SIRPα is an inhibitory receptor expressed only on myeloid cells and dendritic cells. Binding of CD47 to SIRPα delivers a “don’t eat me” signal to suppress phagocytosis. Tumor cells frequently overexpress CD47 to evade macrophage-mediated destruction. To ...
Manufactured by:MR Solutions based inGuildford, UNITED KINGDOM
The MRS*PET INSERT, designed by MR Solutions, facilitates simultaneous PET/MR imaging, enabling the acquisition of multi-parametric information from the same subject with precision. Built to integrate seamlessly with cryogen-free MR systems up to 9.4 Tesla, it offers flexibility in research settings due to its removable nature. This product can function independently of the MR system, effectively ...
by:Sorrento Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
Sorrento utilizes a proprietary knock-out knock-in (KOKI) technology to modify normal healthy donor derived T cells to genetically engineer them to express the dimeric antigen receptor into T-cell receptor (TCR) alpha chain constant region (TRAC). In this manner, TRAC is knocked out and antigen is knocked into its locus. The Dimeric Antigen Receptor (DAR) utilizes a Fab instead of the scFv ...
Manufactured by:NeuroMD based inNorth Miami Beach, FLORIDA (USA)
The most advanced, FDA-cleared system to restore your lower back health and provide lasting pain relief. Equipped with pre-set, clinically studied NMES parameters, the Corrective Therapy Device® delivers proven electrical stimulation to correct the source of the pain. Get started on the path to relief during our biggest sale ever with savings ...
by:Verb Biotics based inBoston, MASSACHUSETTS (USA)
Yso2 is a preclinical program targeting Crohn’s disease. It aims to develop Christensenella gut bacteria as a safe, efficient and groundbreaking oral biotherapy. YSOPIA has identified a lead candidate to relieve Crohn’s disease associated symptoms and slow down disease progression. Discover the articles we published in Scientific Reports: Relizani et al. 2022 and Kropp et al. 2021. ...
Manufactured by:AstraZeneca based inCambridge, UNITED KINGDOM
IVX-121 targets respiratory syncytial virus (RSV), a major cause of viral pneumonia for which no vaccine has been FDA approved. IVX-121 incorporates a stabilized prefusion F antigen licensed from NIAID/NIH (DS-Cav1; Science 2019). RSV F is known to undergo major structural changes that allow viral entry into the host cell, and during that process, critical protective epitopes are lost. Protein ...
Manufactured by:Mirus Bio LLC based inMadison, WISCONSIN (USA)
TransIT-VirusGEN SELECT Transfection Reagent is designed to enhance delivery of packaging and transfer vector DNA to suspension and adherent HEK 293 cell types in order to increase production of recombinant lentivirus and adeno-associated virus (AAV). Key benefits of TransIT-VirusGEN SELECT Transfection Reagent include: Performance – Efficient DNA delivery for large-scale production of ...
Manufactured by:Elpiscience based inShanghai, CHINA
LAG3 is an immune checkpoint receptor known to suppress T cell activation. We designed ES005 to block LAG3 ligands, including MHC class II and FGL1. Through unique epitope binding, ES005 is able to recognize human LAG3 with high affinity. In preclinical studies, ES005 inhibited tumor growth both as a monotherapy and in combination with a PD-1 ...