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Model Gelacell -3D Nanofibrous Scaffolds
Gelacell™ is a non-woven highly porous scaffold specially designed for in vitro 3D cell culture and tissue engineering. It has a unique nanofibrous structure that closely mimics the natural extracellular matrix. Designed as a non-woven, highly porous scaffold, Gelacell™ offers exceptional biocompatibility and non-toxicity across a variety of cell types. Gelacell™ is produced using patented halospinning technology that provides unprecedented 3D architecture with extensive surface area for cellular activities. Compatible with various cell lines and culture conditions.High surface-to-volume ratio
Halospun nanofibers have an extremely high surface-to-volume ratio, which enhances cell attachment, growth, and differentiation.
Porosity
The interconnected porous structure of these nanofibers facilitates efficient nutrient and oxygen transport to cells, which is critical for cell survival and proliferation.
Biomimicry
Nanofibers, due to their scale and structure, can effectively mimic the extracellular matrix (ECM) of various tissues, providing a more natural environment for cells.
Customizability
Fiber diameter, alignment, and density can be controlled during the halospinning process, allowing for customization to suit specific cell types and applications.
Enhanced cell interactions
Due to their morphology, halospun nanofibers promote superior cell-to-cell and cell-to-fiber interactions, encouraging the formation of 3D cell networks.
Flexibility in material selection
Halospun nanofibers can be made from a wide variety of polymers, both natural and synthetic, allowing for a range of mechanical and chemical properties to suit different cell culture needs.
- Acts as an in-vitro extracellular matrix
- Preserves the natural cell structure
- Enhances cell-to-cell and cell-to-matrix interactions
- Supports optimal cell differentiation
- Porous structure facilitates nutrient diffusion
- Protects cells during laboratory practices
In traditional 2D in vitro systems, cells tend to flatten and stretch in a monolayer, creating stress and modifying their natural behavior
A 3D in vitro scaffold helps preserve the natural shape of the cells, reduces the stress conditions, and allows for the structural conformation found in native tissues. In a 3D system, cells retain more of their original functions, surface activity, and natural complex interactions