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In Vivo Cell Equipment & Supplies

87 equipment items found

Model EDIT-301 - Ex Vivo Gene Editing Cell Medicines

Model EDIT-301 - Ex Vivo Gene Editing Cell Medicines

Manufactured by:Editas Medicine   based inCambridge, MASSACHUSETTS (USA)
EDIT-301 is an experimental cell therapy medicine under investigation for the treatment of severe sickle cell disease (SCD) and transfusion-dependent beta thalassemia (TDT). EDIT-301 consists of patient-derived CD34+ hematopoietic stem and progenitor cells edited at the gamma globin gene (HBG1 and HBG2) promoters, where naturally occurring fetal hemoglobin (HbF) inducing mutations reside, by a ...
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Sana - Hematopoietic Stem Cells - Fusogen Technology

Sana - Hematopoietic Stem Cells - Fusogen Technology

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Hemoglobinopathies: Sickle cell disease, ...
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Sana - Model SG295 (CD8/CD19) - T cells - Fusogen Technology

Sana - Model SG295 (CD8/CD19) - T cells - Fusogen Technology

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Oncology: Non-Hodgkin lymphoma (NHL), Acute lymphoblastic leukemia (ALL), Chronic lymphocytic leukemia ...
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Sana - Model SG242 (CD4/CD19) - T cells - Fusogen Technology

Sana - Model SG242 (CD4/CD19) - T cells - Fusogen Technology

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Oncology: Non-Hodgkin lymphoma (NHL), Acute lymphoblastic leukemia (ALL), Chronic lymphocytic leukemia ...
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Sana - Model SG328 - Hepatocytes - Fusogen Technology

Sana - Model SG328 - Hepatocytes - Fusogen Technology

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Liver-related genetic disorders: Ornithine transcarbamylase deficiency ...
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Sana - Model SG239 (CD8/BCMA) - T cells - Fusogen Technology

Sana - Model SG239 (CD8/BCMA) - T cells - Fusogen Technology

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Oncology: Multiple ...
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Sana - Model SG221 (CD4/BCMA) - T cells - Fusogen Technology

Sana - Model SG221 (CD4/BCMA) - T cells - Fusogen Technology

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Oncology: Multiple ...
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Sana - Model SC291 (CD19) - T cells - Hypoimmune Technology: Donor-derived

Sana - Model SC291 (CD19) - T cells - Hypoimmune Technology: Donor-derived

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Oncology: Non-Hodgkin lymphoma (NHL), Acute lymphoblastic leukemia (ALL), Chronic lymphocytic leukemia ...
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Sana - Model SC276 (CD22 (+CD19)) - T Cells - Hypoimmune Technology: Donor-derived

Sana - Model SC276 (CD22 (+CD19)) - T Cells - Hypoimmune Technology: Donor-derived

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Oncology; Non-Hodgkin lymphoma (NHL), Acute lymphoblastic leukemia (ALL), Chronic lymphocytic leukemia ...
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Sana - Model SC255 (BCMA) - T Cells - Hypoimmune Technology: Donor-derived

Sana - Model SC255 (BCMA) - T Cells - Hypoimmune Technology: Donor-derived

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Oncology - Multiple ...
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Sana - Model SC451 - Beta Cells - Hypoimmune Technology: Stem Cell-Derived

Sana - Model SC451 - Beta Cells - Hypoimmune Technology: Stem Cell-Derived

Manufactured by:Sana Biotechnology   based inSeattle, WASHINGTON (USA)
Diabetes: Type 1 ...
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Model Gelacell - 3D Nanofibrous Scaffolds

Model Gelacell - 3D Nanofibrous Scaffolds

by:Gelatex Technologies   based inTallinn, ESTONIA
Gelacell™ is a non-woven highly porous scaffold specially designed for in vitro 3D cell culture and tissue engineering. It has a unique nanofibrous structure that closely mimics the natural extracellular matrix. Designed as a non-woven, highly porous scaffold, Gelacell™ offers exceptional biocompatibility and non-toxicity across a variety of cell types. Gelacell™ is produced using patented ...
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VelociHum - Immunodeficient Mouse Platform

VelociHum - Immunodeficient Mouse Platform

Manufactured by:Regeneron Pharmaceuticals Inc.   based inTarrytown, NEW YORK (USA)
VelociHum is our immunodeficient mouse platform that can be used to accurately test human therapeutics against human immune cells and to study human tumor models. Through genetic humanizations, VelociHum mice have been optimized to allow for better development of human immune cells in vivo, as well as to allow for engraftment of primary ...
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Myeloid - In Vivo Myeloid Programming with mRNA

Myeloid - In Vivo Myeloid Programming with mRNA

by:Myeloid Therapeutics   based inCambridge, MASSACHUSETTS (USA)
Myeloid’s novel in vivo engineering platform specifically targets and activates myeloid cells to elicit broader anti-tumor adaptive immunity. Through this approach, Myeloid demonstrates that delivery of lipid-nanoparticles (LNPs) encapsulating mRNA results in uptake and selective expression by myeloid cells in vivo, leading ...
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T-Cure - Receptor Therapy T Cell

T-Cure - Receptor Therapy T Cell

Manufactured by:T-Cure BioScience, Inc.   based inSherman Oaks, CALIFORNIA (USA)
T cell engineering with TCRs is a growing area of immuno-oncology with recent breakthroughs in clinical settings. The T-Cure approach involves identifying and isolating a high avidity TCR which specifically recognizes an intracellular or cell-surface target in solid tumors. This TCR is then typically introduced into a viral vector that can deliver the TCR into ...
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Sigma-Aldrich HyStem - Model HYS020 - Cell Culture Scaffold Kit

Sigma-Aldrich HyStem - Model HYS020 - Cell Culture Scaffold Kit

Manufactured by:Sigma-Aldrich   based inBellefonte, PENNSYLVANIA (USA)
Customizable and free of animal components, Hystem hydrogel cell culture scaffolds provide a complex, three dimensional environment in which cells are able to proliferate, much as they would in vivo. Customizable - each distinct cell type in a multicellular organism has its own unique microenvironment. Hystem offers the ...
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BTX - Model ECM 830 - Square Wave Electroporation System

BTX - Model ECM 830 - Square Wave Electroporation System

Manufactured by:BTX - Harvard Bioscience, Inc.   based inHolliston, MASSACHUSETTS (USA)
The ECM 830 is a versatile electroporation system suitable for applications for gene, drug and protein delivery including: CRISPR, mammalian cells, in vivo, ex vivo, in ovo tissue, ex plant and nuclear ...
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Myeloid - Model MT-302 (TROP2-FcA LNP) - In Vivo Programming Pipeline

Myeloid - Model MT-302 (TROP2-FcA LNP) - In Vivo Programming Pipeline

by:Myeloid Therapeutics   based inCambridge, MASSACHUSETTS (USA)
Emerging from the Company’s proprietary ATAK™ CAR receptor library, Myeloid’s novel in vivo engineering platform specifically targets and activates myeloid cells to elicit broader anti-tumor adaptive immunity. Through this approach, Myeloid demonstrates that delivery of lipid-nanoparticles (LNPs) encapsulating mRNA results in uptake and ...
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MedChemExpress - Model Tributyrin - 60-01-5

MedChemExpress - Model Tributyrin - 60-01-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing ...
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MedChemExpress - Model Talacotuzumab - 1826831-79-1

MedChemExpress - Model Talacotuzumab - 1826831-79-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Talacotuzumab has KDs of 0.43 nM, 188 nM, 46 nM, 16.8 nM for CD123, CD32b/c, CD16-158F, CD16-158V, respectively. Talacotuzumab inhibits IL-3 binding to CD123, antagonizing IL-3 signaling in target cells. Talacotuzumab has mutated the Fc region to increase affinity for CD16 (FcγRIIIa), thereby enhancing antibody-dependent cell-mediated cytotoxicity (ADCC). ...
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