VelociHum is our immunodeficient mouse platform that can be used to accurately test human therapeutics against human immune cells and to study human tumor models. Through genetic humanizations, VelociHum mice have been optimized to allow for better development of human immune cells in vivo, as well as to allow for engraftment of primary ...

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Myeloid - In Vivo Myeloid Programming with mRNA

by:Myeloid Therapeutics based inCambridge, MASSACHUSETTS (USA)

Myeloid’s novel in vivo engineering platform specifically targets and activates myeloid cells to elicit broader anti-tumor adaptive immunity. Through this approach, Myeloid demonstrates that delivery of lipid-nanoparticles (LNPs) encapsulating mRNA results in uptake and selective expression by myeloid cells in vivo, leading ...

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Sigma-Aldrich HyStem - Model HYS020 - Cell Culture Scaffold Kit

Manufactured by:Sigma-Aldrich based inBellefonte, PENNSYLVANIA (USA)

Customizable and free of animal components, Hystem hydrogel cell culture scaffolds provide a complex, three dimensional environment in which cells are able to proliferate, much as they would in vivo. Customizable - each distinct cell type in a multicellular organism has its own unique microenvironment. Hystem offers the ...

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T-Cure - Receptor Therapy T Cell

Manufactured by:T-Cure BioScience, Inc. based inSherman Oaks, CALIFORNIA (USA)

T cell engineering with TCRs is a growing area of immuno-oncology with recent breakthroughs in clinical settings. The T-Cure approach involves identifying and isolating a high avidity TCR which specifically recognizes an intracellular or cell-surface target in solid tumors. This TCR is then typically introduced into a viral vector that can deliver the TCR into ...

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Model Gelacell - 3D Nanofibrous Scaffolds

by:Gelatex Technologies based inTallinn, ESTONIA

Gelacell™ is a non-woven highly porous scaffold specially designed for in vitro 3D cell culture and tissue engineering. It has a unique nanofibrous structure that closely mimics the natural extracellular matrix. Designed as a non-woven, highly porous scaffold, Gelacell™ offers exceptional biocompatibility and non-toxicity across a variety of cell types. Gelacell™ is produced using patented ...

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Emulate - Lung-Chip

Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)

Study lung physiology, disease, and the effect of drug candidates. A more human-relevant model for studying pulmonary physiology, with primary human cells in a lung-specific microenvironment. We are currently developing two distinct models of the human lung—the Alveolus Lung-Chip and the Airway Lung-Chip—to capture the specific tissue architecture and function of different lung ...

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Viscoll - Dura Collagen Membrane for The Repair of Dura Defects

Manufactured by:Viscoll based inMoscow, RUSSIA

The product is a soft, pliable, rounded, porous white matrix made of highly purified native type I collagen isolated from porcine tendons. The product is intended for use in surgical procedures that require replacement or repair of the patient’s dura ...

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$Eutilex - Model EU301(MVR CAR-T) - Relapsed and Refractory B Cell Leukemia and B Cell Lymphoma$

Eutilex - Model EU301(MVR CAR-T) - Relapsed and Refractory B Cell Leukemia and B Cell Lymphoma

Manufactured by:Eutilex Co.,Ltd. based inSeoul, SOUTH KOREA

MVR CAR-T can be used against HLA-DR positive cancer, as well as B cell malignancy. The epitopes recognized by HLA-DR are not shed or internalized, enabling stable binding to human lymphoma cells. MVR CAR-T can also be used in patients who relapse after CD19 CAR-T treatment. Reduction of cytokine secretion due to selective killing of tumor ...

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Myeloid - Model MT-302 (TROP2-FcA LNP) - In Vivo Programming Pipeline

by:Myeloid Therapeutics based inCambridge, MASSACHUSETTS (USA)

Emerging from the Company’s proprietary ATAK™ CAR receptor library, Myeloid’s novel in vivo engineering platform specifically targets and activates myeloid cells to elicit broader anti-tumor adaptive immunity. Through this approach, Myeloid demonstrates that delivery of lipid-nanoparticles (LNPs) encapsulating mRNA results in uptake and ...

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Eutilex - Model EU501 (HER2 x 4-1BB) - 4-1BB mAb-based, Tumor Antigen

Manufactured by:Eutilex Co.,Ltd. based inSeoul, SOUTH KOREA

4-1BB mAb-based, tumor antigen targeting bispecific ...

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