Himed - Synthetic Hydroxyapatite (HA) for Biomedical Applications
Himed specializes in high-quality synthetic hydroxyapatite (HA), a calcium phosphate biomaterial known for its biocompatibility and bioactivity, making it highly suitable for bone regeneration, dental reconstruction, and orthopedic implants. Unlike natural forms, Himed's HA is synthetically manufactured to ensure consistent stoichiometry, essential for precise clinical and engineering applications. The company's HA is produced under GMP guidelines and conforms to ISO 13485:2016 and ASTM F1185 standards with a purity of ≥96%, ensuring reliable batch-to-batch consistency demanded by medical and dental markets. Offering a comprehensive array of forms including powders, granules, cast solids, and porous shapes, Himed's HA supports diverse applications from scaffolds to implant coatings. Furthermore, the material's tunable attributes, like particle size and crystallinity, enhance its role in composite systems, often coupled with polymers like PEEK for improved mechanical properties. Himed also provides customization services, allowing for engineered performance tailored to specific needs.
Hydroxyapatite (HA) is a naturally occurring calcium phosphate, and the primary mineral found in human bone and tooth enamel. Its chemical and structural similarity to the hard tissues within our bodies gives it exceptional biocompatibility and bioactivity. These characteristics make HA one of the most studied and widely applied materials in bone regeneration, dental reconstruction, and orthopedic implant design.
Himed specializes in the production of high-quality hydroxyapatite powders, granules, and forms. We manufacture all of our hydroxyapatite under GMP guidelines that are in conformance with ISO 13485:2016—employing exacting chemical processes to ensure the uniformity, purity, and batch-to-batch consistency that our clients in the medical and dental markets require.
Unlike natural HA—which is extracted from animal or marine sources, and therefore subject to compositional variability—our synthetic HA provides a reproducible stoichiometric structure that can be precisely tailored to meet diverse clinical and engineering requirements. This level of control allows our team to optimize critical attributes such as particle size, crystallinity, surface area, and ionic composition.
Whether enhancing cellular adhesion in a scaffold, improving coating performance on a titanium implant, or tuning resorption behavior in a bone filler, Himed’s HA serves as a stable and adaptable platform for advanced biomedical applications.
Unlike natural HA—which is extracted from animal or marine sources, and therefore subject to compositional variability—our synthetic HA provides a reproducible stoichiometric structure that can be precisely tailored to meet diverse clinical and engineering requirements. This level of control allows our team to optimize critical attributes such as particle size, crystallinity, surface area, and ionic composition.
Whether enhancing cellular adhesion in a scaffold, improving coating performance on a titanium implant, or tuning resorption behavior in a bone filler, Himed’s HA serves as a stable and adaptable platform for advanced biomedical applications.
Hydroxyapatite’s value as a biomaterial lies in its unique combination of biological affinity and tunable properties. As a synthetic analog of natural bone mineral, hydroxyapatite is highly biocompatible, osteoconductive, and chemically stable—making it ideal for applications where predictable integration with hard tissue is required. Himed produces hydroxyapatite under tightly controlled conditions to ensure reproducibility and enable tailored performance across orthopedic, dental, and laboratory use cases.
- BIOCOMPATIBILITY: Non-inflammatory, non-immunogenic
- OSTEOCONDUCTIVITY: Promotes bone ingrowth and osteoblast adhesion
- SURFACE REACTIVITY: Supports matrix protein binding and early mineralization
- POROSITY: Adjustable to support vascularization and cellular infiltration
- SOLUBILITY: Low, but tunable for controlled resorption over time