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Cancerous Mutation Equipment & Supplies
31 equipment items found
Manufactured by:Taiho Oncology, Inc. based inPrinceton, NEW JERSEY (USA)
Tumors with specific FGFR aberrations: Solid tumors, Gastric cancer, Myelolymphoid neoplasms PHASE ...
Manufactured by:TIB Molbiol Syntheselabor GmbH based inBerlin, GERMANY
In 2005 we developed our first LightMix Kit detecting bird flu Influenza A H5N1. Since then, we have created many kits testing for different pathogens, hematology markers, genetic mutations and polymorphisms. ...
Manufactured by:ViennaLab Diagnostics GmbH based inVienna, AUSTRIA
BRAF encodes a serine/threonine protein kinase, which plays an important role in signaling pathways involved in cell proliferation and differentiation. Determination of BRAF V600 mutational status is recommended in metastatic colorectal cancer (mCRC) at the same time as RAS mutational status for prognostic assessment (and/or potential selection ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
FocuSCOPE is a high-throughput single cell multi-omics sequencing solution that can detect both genetic variants and transcriptome from the same single cells. Thus, FocuSCOPE® provided a tool to decipher the connection between genotype and phenotype at single cell ...
Manufactured by:Biocept based inSan Diego, CALIFORNIA (USA)
his kit detects BRAF V600 mutations in DNA derived from blood plasma or FFPE tissue sections to give insight into cancer characteristics and provide Biomarker status of tumors such as ...
Manufactured by:TxinnoBioscience Inc. based inYongin-si, SOUTH KOREA
RAS GTPase family has 3 members encoding KRAS, HRAS and NRAS proteins which are involved in controlling normal growth signal. RAS GTPases are also well-known oncogenes that drive tumorigenesis when mutation is ...
Manufactured by:EntroGen, Inc. based inWoodland Hills, CALIFORNIA (USA)
The KRAS gene encodes a small GTPase that plays a key role in transducing signals from the epidermal growth factor receptor (EGFR) to downstream effectors. KRAS mutations have been commonly found in several types of human malignancies, such as metastatic colorectal cancer (mCRC), lung adenocarcinoma and thyroid cancer. The most common ...
Manufactured by:Sysmex Partec GmbH based inGoerlitz, GERMANY
Highly sensitive down to 0.06 % MAF, Able to detect 6 MM with 95 % confidence across all mutations (absolute quantification), High flexibility of between 2-16 samples/run, Fast TAT (2 days), Convenient software. Plasma-SeqSensei (PSS) BC RUO Kit allows for the highly sensitive and specific detection of mutations in circulating tumour DNA (ctDNA) from the plasma ...
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
Tulmimetostat is a second-generation EZH2 inhibitor that has been designed to achieve comprehensive target coverage through extended on-target residence time. EZH2 acts as an epigenetic writer and normally places one or more methyl groups on a histone protein, leading to the suppression of gene expression. Some cancers depend on an abnormal pattern of gene expression and re-direct EZH2 to genes ...
Manufactured by:Biocept based inSan Diego, CALIFORNIA (USA)
This kit detects EGFR mutations in DNA derived from blood plasma or FFPE tissue sections to give insight into cancer characteristics and provide Biomarker status of tumors such as non-small cell lung ...
Manufactured by:Amoy Diagnostics Co., Ltd. based inXiamen, CHINA
The phosphoinositide-3 -kinase catalytic alpha (PIK3CA) gene produces the p110 alpha (pl 10a) protein, which is one subunit of an enzyme called phosphatidylinositol 3-kinase (PI3K). PI3K plays a key role ofPI3K/Akt signaling pathway in numerous cellular processes critical for cancer progression, including metabolism, growth, survival, and motility. Somatic ...
Manufactured by:OncoDNA S.A. based inGosselies, BELGIUM
In addition, it sequences a fixed panel of 40 genes associated with response/resistance to targeted therapies and immunotherapy, and/or frequently mutated in cancer. In 2013, OncoDNA became the first company to launch a personalized liquid biopsy ...
Manufactured by:Hemogenyx Pharmaceuticals plc based inLondon, UNITED KINGDOM
Hemogenyx Pharmaceuticals utilizes postnatal human hemogenic endothelial cells (Hu-PHEC cells), discovered by Hemogenyx Pharmaceuticals’ Co-Founder Dr Vladislav Sandler, to generate cancer-free hematopoietic stem cells (HSC) for use in transplants to treat blood cancers with superior results. A patent for Dr Sandler’s work was issued in the US in February ...
Manufactured by:Elicio Therapeutics based inBoston, MASSACHUSETTS (USA)
ELI-007 is a multivalent lymph node–targeted AMP peptide vaccine developed to target BRAF gene mutations. The BRAF gene is part of an intracellular signaling pathway that drives cell growth and division.1 BRAF mutations can lead to uncontrolled cell growth and ultimately cancer. BRAF mutations are present in ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection of 56 cancer-related genes, including 3000 COSMIC mutation loci. Guiding individualized diagnosis and treatment of pan-cancera ...
Manufactured by:Biocept based inSan Diego, CALIFORNIA (USA)
Biocept’s Target Selector™ molecular assay kits detect key oncogene mutations through the analysis of both Formalin-Fixed Paraffin-Embedded (FFPE) tissue gained from surgical biopsies as well as circulating tumor DNA (ctDNA) gained from blood-based liquid biopsies. The EGFR pathway can include mutations that are among the most frequently evaluated ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:KRAS,BRAF,NRAS,PIK3CA,TP53,DYPD,ERBB2,UGT1A1 and MSI（8 genes +MSI）. Detection Significance:Guiding individualized diagnosis and treatment of colorectal ...
Manufactured by:EntroGen, Inc. based inWoodland Hills, CALIFORNIA (USA)
PIK3CA Mutations and CancerThe PIK3CA gene encodes the p110a subunit of phosphatidyl 3-kinase, a lipid kinase involved in cell growth, proliferation, motility and survival. It has a central role in the PI3K-AKT-mTOR pathway. Somatic mutations in the PIK3CA gene have been implicated in the pathogenesis of several cancers, including colon ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
The test kit is based on high-throughput sequencing, covering all common genes related to thyroid tumor typing, prognosis, medication and genetics recommended in NCCN guidelines, CSCO guidelines and expert consensus. DNA level: 16 genes; RNA level: 209 fusion forms of 87 genes. Detection Significance:Predicting prognosis ;Auxiliary diagnosis;Guiding the selection of BRAF/MEK、NTRK、ALK inhibitors ...
Manufactured by:Qualigen Therapeutics, Inc. based inCarlsbad, CALIFORNIA (USA)
Our RAS-F portfolio includes lead and back-up small molecules that suppress the interaction of endogenous RAS with c-RAF, upstream of the KRAS, HRAS, and NRAS effector pathways. This potentially enables a differentiated, RAS-targeted strategy for inhibiting the MAPK, PI3K, and TOR pathways that are implicated in cancer cell proliferation, survival, and differentiation (see figure). RAS itself ...