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Medchemexpress Drug Interaction Equipment & Supplies

18 equipment items found

MedChemExpress - Model N-Acetylcarnosine - 56353-15-2

MedChemExpress - Model N-Acetylcarnosine - 56353-15-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human ...
CONTACT SUPPLIER

MedChemExpress - Model Ritonavir - 155213-67-5

MedChemExpress - Model Ritonavir - 155213-67-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 ...
CONTACT SUPPLIER

MedChemExpress - Model Irdabisant - 1005402-19-6

MedChemExpress - Model Irdabisant - 1005402-19-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with Ki values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low inhibitory activity against hERG current with an IC50 of 13.8 μM. Irdabisant has cognition-enhancing and wake-promoting activities in the ...
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MedChemExpress - Model Levosimendan - 141505-33-1

MedChemExpress - Model Levosimendan - 141505-33-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart ...
CONTACT SUPPLIER

MedChemExpress - Model Flucytosine - 2022-85-7

MedChemExpress - Model Flucytosine - 2022-85-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer ...
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MedChemExpress - Model Verteporfin - 129497-78-5

MedChemExpress - Model Verteporfin - 129497-78-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis[1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting ...
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MedChemExpress - Model Loxoprofen - 68767-14-6

MedChemExpress - Model Loxoprofen - 68767-14-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor ...
CONTACT SUPPLIER

MedChemExpress - Model Docetaxel Trihydrate - 148408-66-6

MedChemExpress - Model Docetaxel Trihydrate - 148408-66-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell ...
CONTACT SUPPLIER

MedChemExpress - Model Cryptotanshinone - 35825-57-1

MedChemExpress - Model Cryptotanshinone - 35825-57-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 ...
CONTACT SUPPLIER

MedChemExpress - Model Phenothiazine - 92-84-2

MedChemExpress - Model Phenothiazine - 92-84-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological ...
CONTACT SUPPLIER

MedChemExpress - Model Abemaciclib methanesulfonate - 1231930-82-7

MedChemExpress - Model Abemaciclib methanesulfonate - 1231930-82-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC50s of 2 nM and 10 nM for CDK4 and CDK6, ...
CONTACT SUPPLIER

MedChemExpress - Model Secnidazole - 3366-95-8

MedChemExpress - Model Secnidazole - 3366-95-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. ...
CONTACT SUPPLIER

MedChemExpress - Model Loxoprofen sodium - 80382-23-6

MedChemExpress - Model Loxoprofen sodium - 80382-23-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium can reduce atherosclerosis and shows antitumor ...
CONTACT SUPPLIER

MedChemExpress - Model MKC3946 - 1093119-54-0

MedChemExpress - Model MKC3946 - 1093119-54-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
MKC3946 is a potent IRE1α inhibitor, used for cancer ...
CONTACT SUPPLIER

MedChemExpress - Model AZD9056 hydrochloride - 345303-91-5

MedChemExpress - Model AZD9056 hydrochloride - 345303-91-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing ...
CONTACT SUPPLIER

MedChemExpress - Model Cladribine - 4291-63-8

MedChemExpress - Model Cladribine - 4291-63-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple ...
CONTACT SUPPLIER

MedChemExpress - Model Busulfan - 55-98-1

MedChemExpress - Model Busulfan - 55-98-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic ...
CONTACT SUPPLIER

MedChemExpress - Model Docetaxel - 114977-28-5

MedChemExpress - Model Docetaxel - 114977-28-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer ...
CONTACT SUPPLIER
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