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- MouthLab - Mobile Monitoring System for Biopharmaceutical
- MouthLab - Mobile Monitoring System for Contract Research Organizations (CROs)
- Klarity - Built Therapeutic Platform Technologies for Gastrointestinal Disease
- Klarity - Built Therapeutic Platform Technologies for Neurological Disorders
- Klarity - Built Therapeutic Platform Technologies for Metabolism
Human Diseases Equipment Supplied In North America
44 equipment items found
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in ...
Manufactured by:Regeneron Pharmaceuticals Inc. based inTarrytown, NEW YORK (USA)
This enables unprecedented speed and capacity for the validation of therapeutic targets and the creation of animal models of human disease. We have a long history and deep expertise in mouse genetics — in 2006, VelociGene was selected by the National Institutes of Health (NIH) as part of its Knockout Mouse Project, an unprecedented effort to determine the ...
Manufactured by:Trailhead Biosystems Inc. based inBeachwood, OHIO (USA)
We are developing human endothelial cells from human (non-embryo) induced pluripotent stem cells (iPSCs). Our novel protocol will allow us to make endothelial cells at scale. We will make our endothelial cells available for drug discovery, organ or tissue printing, high throughput or high content screening, toxicity and efficacy testing, and ...
Manufactured by:Xenobiotic Detection Systems International, Inc. based inDurham, NORTH CAROLINA (USA)
The Ah receptor (AhR) is a ligand-activated transcription factor that mediates the induction or inhibition of expression of a diverse spectrum of genes resulting in a ligand-specific spectrum of biological and/or toxicological effects. The AhR also has been shown to play a key regulatory role in endogenous physiological responses as well as human disease and it ...
Manufactured by:Caprico Biotechnologies, Inc. (CBI) based inNorcross, GEORGIA (US) (USA)
EAPII has been demonstrated to have promiscuous protein associations, broad responsiveness to various extracellular signals, and pleiotropic functions in the development of human diseases including cancer and neurodegenerative ...
Manufactured by:Quidel Corporation based inSan Diego, CALIFORNIA (USA)
Bordetella is a family of small gram-negative bacterial pathogens that cause respiratory tract infections in humans and animals.1 Nine species of Bordetella have been identified to date, but Bordetella pertussis causes most of the human disease and only three additional members, B. bronchiseptica, B. parapertussis, and B. holmesii have been ...
Manufactured by:AllCells based inAlameda, CALIFORNIA (USA)
CD34+ HSPCs can be isolated from mobilized peripheral blood, bone marrow, and umbilical cord blood. Clinical HSPC transplantation is used to treat blood cancers (leukemia, myeloma and lymphomas), autoimmune diseases, and more. Gene-modified HSPCs (in vivo or ex vivo) are a promising new modality for a growing number of human diseases including ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Protectin D1 also serves as a specialized pro-resolving mediator, exhibiting effective in vivo pro-resolving activity in various human disease models. Additionally, Protectin D1 is an inhibitor of NALP3 inflammasomes and regulates the PI3K/AKT and HIF-1α signaling pathways. Protectin D1 exerts anti-inflammatory effects by reducing ROS levels, inhibiting the ...
Manufactured by:Advanced Electrophoresis Solutions Ltd. (AES) based inCambridge, ONTARIO (CANADA)
With our ISO:9001 certification, AES is proud to offer a comprehensive range of critical consumables, including proprietary cartridges, ampholytes, pI markers, electrolytes, and general solutions and consumables. In particular, we are pleased to supply high-quality 0.5% and 1% Methyl Cellulose (MC) solutions for icIEF analysis. Our MC solutions are fast, long-lasting, and compatible with ...
Manufactured by:Auro Vaccines LLC based inPearl River, NEW YORK (USA)
As part of its comprehensive Public Health and Biodefense vaccine franchise, under a license from the Henry M. Jackson Foundation, Auro Vaccines is developing a subunit vaccine (HeV-sG-V) composed of the envelope glycoprotein of Hendra virus for the prevention of Nipah virus (NiV) ...
Manufactured by:Aidar Health based inBaltimore, MARYLAND (USA)
MouthLab is a non-invasive, hand-held. Rapid Health Assessment device that is designed to be used at home. It is cost-effective and as easy to use as a digital thermometer, yet capable of measuring multiple vital health parameters in under 80 ...
Manufactured by:Aelan Cell Technologies based inSan Francisco, CALIFORNIA (USA)
Adult stem cells have been shown to possess a broad spectrum of immunoregulatory capabilities. They affect both adaptive and innate immunity by secretion of growth factors, chemokines and regulators that promote organ and tissue homeostasis by inducing cell proliferation, angiogenesis, interactions with the immune system and protection against cell ...
Manufactured by:AMS Biotechnology (Europe) Ltd. based inAbingdon, UNITED KINGDOM
Breast cancer with adjacent normal breast tissue array (2012 WHO classification), including pathology grade, TNM and clinical stage (AJCC 7th edition), 12 cases/24 cores, repalcing BR245. Breast carcinoma with adjacent normal breast tissue microarray, containing 10 cases of invasive carcinoma of no special type, 2 adjacent normal breast tissue, duplicate cores per ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Azaindoles and their derivatives exhibit significant biological activities, hence they are widely concerned in terms of drug optimization strategies. The four azaindole positional isomers, which associate a pyridine and a pyrrole ring by a fused C-C bond, possess all of the criteria necessary to be excellent bioisosteres of the indole or purine systems. The physicochemical and pharmacological ...
Manufactured by:SIGA Technologies, Inc. based inNew York, NEW YORK (USA)
Oral TPOXX® (tecovirimat) is the first drug approved by the U.S. Food and Drug Administration (FDA) that is specifically indicated for the treatment of smallpox disease in adults and pediatric patients weighing at least 13 kg. (Prescription Label) TPOXX® inhibits viral maturation of variola virus (the virus that causes smallpox) and other poxviruses by preventing the formation of a ...
Manufactured by:ASC Therapeutics based inMilpitas, CALIFORNIA (USA)
We are developing gene and cell-based therapies. Gene therapy is addition, alteration or removal of genes within cells and biological tissues to treat diseases. A correcting genetic agent can be delivered directly to the blood stream in vivo, or to the affected tissue in situ, or the targeted cells can be modified ex vivo and injected back to the patients. Cell-based therapies involve injecting ...
Manufactured by:Notitia Biotechnologies based inMonmouth Junction, NEW JERSEY (USA)
Based on these Four Pillars and the ground-breaking scientific discoveries, we have developed the Foundation Guild™ Microbiome R&D Platform that serves as the basis of various technologies for promoting the Foundation Guild™ in patients and the generally healthy ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Autophagy is an intracellular degradation system that delivers cytoplasmic constituents to the lysosome. Autophagy plays a wide variety of physiological and pathophysiological roles. Different selective forms of autophagy have been identified and characterized, leading to the specific degradation of organelles or pathogens. These selective pathways include the autophagic degradation of ...
Manufactured by:Precision For Medicine, Inc. based inFrederick, MARYLAND (USA)
PBMCs are a vital component to understanding human immune function and disease response. Variability in quality, availability, and purity can derail a research study. At Precision for Medicine, PBMCs are collected and processed within our FDA-registered facility to ensure optimal cell yields, viability, and quality. ...
Manufactured by:Kallyope Inc. based inNew York City, NEW YORK (USA)
At Kallyope, we are pioneering the science and understanding of gut and gut-brain biology to create medicines that transform human ...