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Innate Immunity Equipment Supplied In Usa California
12 equipment items found
by:Vir Biotechnology, Inc. based inSan Francisco, CALIFORNIA (USA)
Moving beyond more traditional approaches that are used to evoke adaptive immunity or that directly target pathogens, where the development of resistance can occur, we plan to target host proteins as a means of creating host-directed therapies with high barriers to resistance. We believe that by leveraging the power of innate immunity, we can ...
Manufactured by:Brooklyn ImmunoTherapeutics (BTX) based inSan Diego, CALIFORNIA (USA)
Expressing reprogramming proteins by repeated transfection with protein-encoding RNA could avoid the limitations of both DNA and protein-based reprogramming techniques. However, transfection with long, in vitro-transcribed RNA triggers a potent innate immune response in human cells, even when the RNA is capped and polyadenylated to mimic eukaryotic mRNA. To ...
Manufactured by:Aelan Cell Technologies based inSan Francisco, CALIFORNIA (USA)
Adult stem cells have been shown to possess a broad spectrum of immunoregulatory capabilities. They affect both adaptive and innate immunity by secretion of growth factors, chemokines and regulators that promote organ and tissue homeostasis by inducing cell proliferation, angiogenesis, interactions with the immune system and protection against ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
Targeting this chronokine may cause improvements via two mechanisms—a broad anti-inflammatory mechanism and an immune modulatory mechanism through the body’s innate immune ...
Manufactured by:Vala Sciences based inSan Diego, CALIFORNIA (USA)
Background: Microglia are central nervous system innate immune support cells that function remarkably like peripheral macrophages [1]. Microglia continually monitor neuronal function through direct cell-cell contacts and exert neuroprotective effects in response to stress [2]. By maintaining brain homeostasis, clearing cellular debris [3], pruning synapses [4], ...
Manufactured by:Senti Biosciences based inSouth San Francisco, CALIFORNIA (USA)
Natural Killer (NK) cells are essential components of the immune system, playing an important role in the body’s defensive response against tumors and infected cells. NK cells constantly patrol the body to detect and neutralize foreign cells. Senti Bio believes there are several advantages that NK cells confer in relation to other potential immune cell ...
Manufactured by:Nkarta, Inc. based inSouth San Francisco, CALIFORNIA (USA)
Cell therapy, a new approach that uses immune cells to attack tumors, has emerged as one of the most promising breakthroughs in cancer treatment. First generation approaches have focused on T-cells, which have shown great promise in hematologic malignancies but are plagued with unwanted side effects and, to date, have not shown similar activity in solid tumors. Nkarta was founded ...
Manufactured by:Bio-Rad Laboratories, Inc. (Antibodies) based inHercules, CALIFORNIA (USA)
The dengue virus (DENV), first isolated in 1943, is assigned to the family Flaviviridae, genus Flavivirus. It has four serotypes (DENV-1, DENV-2, DENV-3, and DENV-4) and transmission to humans occurs via the Aedes mosquito, mainly Aedes aegypti. Its global reach has mirrored the spread of Aedes aegypti in tropical and subtropical areas (Messina et al. 2014). It is suggested that 390 million ...
Manufactured by:Adicet Bio based inMenlo Park, CALIFORNIA (USA)
Gamma delta T cells represent a new generation of universal cell therapy. The current engineered autologous alpha beta T cell products have shown significant efficacy in hematological malignancies; however comparable efficacy in solid tumors is yet to be proven. The cell platform and novel targeting approaches Adicet is developing are aimed at harnessing the tumor specific immunity of gamma delta ...
Manufactured by:DxTerity Diagnostics Inc. based inRancho Dominguez, CALIFORNIA (USA)
Autoimmune diseases need analysis tools that go beyond superficial symptoms to recognize the distinct immune system activity of each patient. Modular transcriptome repertoire analysis 1, also known as modular genomics, shows tremendous promise for improving the characterization of patients with autoimmune diseases such as Systemic Lupus Erythematosus (SLE)7, Multiple Sclerosis (MS), Inflammatory ...
Manufactured by:AIVITA Biomedical, Inc. based in, CALIFORNIA (USA)
AIVITA Biomedical is using its patient-specific vaccine platform to develop a rapidly scalable vaccine candidate, AV-COVID-19, for the novel coronavirus (SARS-CoV-2). AIVITA’s personalized vaccine begins with a basic blood draw, from which the recipient’s own immune cells are extracted and loaded with SARS-CoV-2 antigen. The resulting personalized treatment is designed to create ...
Manufactured by:AnaBios Corporation based inSan Diego, CALIFORNIA (USA)
Human Lung Tissue for Translational Research. The human lung is a key organ for multiple therapeutic endpoints, as well as a system that must be evaluated for potential drug-induced toxicities to ensure safety. Modeling the complex interplay of respiratory and vascular components through a reductionist approach has proven to be exceedingly difficult as significant differences exist between ...