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Kidney Research Equipment & Supplies

5 equipment items found

Model Encaleret - Ca Sensing Receptor Antagonist For Autosomal Dominant Hypocalcemia Type 1 (Adh1)

Model Encaleret - Ca Sensing Receptor Antagonist For Autosomal Dominant Hypocalcemia Type 1 (Adh1)

Manufactured by:BridgeBio Pharma, Inc.   based inPalo Alto, CALIFORNIA (USA)
Encaleret is an investigational small molecule antagonist of the calcium sensing receptor (CaSR) being studied in disorders of calcium homeostasis, including autosomal dominant hypocalcemia type 1 (ADH1). Individuals with ADH1 have gain-of-function mutations in the CaSR, causing low serum calcium and a range of debilitating symptoms. ADH1 may also lead to relatively high levels of calcium in ...
CONTACT SUPPLIER

MedChemExpress - Model MnTBAP chloride - 55266-18-7

MedChemExpress - Model MnTBAP chloride - 55266-18-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) ...
CONTACT SUPPLIER

MedChemExpress - Model Ferric citrate - 3522-50-7

MedChemExpress - Model Ferric citrate - 3522-50-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) ...
CONTACT SUPPLIER

MedChemExpress - Model Amiselimod - 942399-20-4

MedChemExpress - Model Amiselimod - 942399-20-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Amiselimod inhibits chronic colitis via inhibiting infiltration of colitogenic Th1 and Th17 cells into the colon. Amiselimod inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. Amiselimodis promising for research of autoimmune ...
CONTACT SUPPLIER

MedChemExpress - Model Molidustat - 1154028-82-6

MedChemExpress - Model Molidustat - 1154028-82-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal ...
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