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Physiological Role Equipment & Supplies
8 equipment items found
Manufactured by:Kaneka Eurogentec S.A. based inSeraing, BELGIUM
α-Synuclein is predominantly expressed in brain, specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express α-Synuclein at very low levels. The physiological role of α-synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be ...
Manufactured by:Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH based inReutlingen, GERMANY
In humans GHBP is formed by receptor shedding of the growth hormone receptor by a metalloprotease (ADAM17). Regulation of biological availability of GH is possibly the physiologic role of of GHBP. Thus, the half-life of GH is prolonged up to 100 minutes by binding to GHBP. GHBP correlates positively with the intraabdominal fat mass and is increased in type II ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Autophagy is an intracellular degradation system that delivers cytoplasmic constituents to the lysosome. Autophagy plays a wide variety of physiological and pathophysiological roles. Different selective forms of autophagy have been identified and characterized, leading to the specific degradation of organelles or pathogens. These selective pathways include the ...
Manufactured by:Mesoblast Ltd. based inMelbourne, AUSTRALIA
Mesoblast’s proprietary mesenchymal lineage adult stem cells (MLCs) are found in multiple tissues where they play vital roles in maintaining tissue ...
Manufactured by:BridgeBio Pharma, Inc. based inPalo Alto, CALIFORNIA (USA)
Encaleret is an investigational small molecule antagonist of the calcium sensing receptor (CaSR) being studied in disorders of calcium homeostasis, including autosomal dominant hypocalcemia type 1 (ADH1). Individuals with ADH1 have gain-of-function mutations in the CaSR, causing low serum calcium and a range of debilitating symptoms. ADH1 may also lead to relatively high levels of calcium in ...
Manufactured by:Noah Chemicals based inSan Antonio, TEXAS (USA)
Acetone, known chemically as C3H6O or dimethyl ketone, is a volatile, colorless, and flammable liquid with a distinct sweet odor. It is widely used as a polar aprotic solvent in various industrial applications including paint, nail polish removers, plastic, fibers, and pharmaceuticals. Beyond its manufactured sources, acetone naturally occurs in trace amounts in plants, trees, volcanic gases, and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
D-Serine-d3 ((R)-Serine-d3) is a deuterium labeled D-Serine (HY-100808). D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, ...
Manufactured by:Roche Diagnostics International AG based inRotkreuz, SWITZERLAND
The Multiplate Analyzer can detect platelet dysfunction and thus may be used to aid in the diagnosis and clinical management of patients with platelet function disorders. ...