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Preclinical Testing Equipment & Supplies
281 equipment items found
Manufactured by:Curi Bio based inSeattle, WASHINGTON (USA)
Get Clinically-relevant Functional Data with 3D Tissues. Mantarray brings functional data into the earliest stages of preclinical testing of new medicines. By providing parallel analysis of 3D engineered muscle tissues with adult-like functional profiles, Mantarray enables the discovery, safety, and efficacy testing of new ...
by:Solinas Medical, Inc. based inSanta Clara, CALIFORNIA (USA)
Designed to reduce leakage after cannulation in AV access systems. Constructed of novel composite material. Available in multiple sizes & shapes that conform to vessels. Preclinical testing demonstrates enhanced durability and resistance to ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for an investigational gene therapy for Gaucher disease type ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for a gene therapy for Pompe disease. We have shown a favorable preclinical safety and efficacy profile in a mouse model of Pompe ...
Manufactured by:Anaveon AG based inBasel, SWITZERLAND
The culmination of our research is ANV419, which is in clinical development. It is a rationally engineered fusion protein that is a stable, antibody-like molecule. ...
Manufactured by:CytomX Therapeutics, Inc. based inSouth San Francisco, CALIFORNIA (USA)
CX-188 is our wholly owned PD-1-targeting Probody therapeutic. As with anti-PD-L1 therapies, PD-1 monotherapy and combinations have been associated with significant toxicities. Our preclinical studies have shown that CX-188 has the potential for an improved therapeutic index relative to PD-1 antibodies. The IND for CX-188 was cleared by the FDA. Following a program and portfolio prioritization, ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for mucopolysaccharidosis type II (MPS II), or Hunter syndrome. The program is being developed in collaboration with Brian Bigger, Ph.D., who has published favorable preclinical data in a mouse model of Hunter ...
Manufactured by:CTIBiotech based inMeyzieu, FRANCE
Using the latest tools in bioengeneering, our researchers are now printing cancer tissues in 3D. These models can be used for highly significant pre-clinical trials and can be produced in 6/48/96 well plates for high throughput ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES004 is a potentially best-in-class antibody targeting pan-allele signal-regulatory protein alpha (SIRPα). SIRPα is an inhibitory receptor expressed only on myeloid cells and dendritic cells. Binding of CD47 to SIRPα delivers a “don’t eat me” signal to suppress phagocytosis. Tumor cells frequently overexpress CD47 to evade macrophage-mediated destruction. To ...
Manufactured by:EMulate Therapeutics, Inc. based inBellevue, WASHINGTON (USA)
Indolor Therapeutics is feasibility (phase I) trial ready for the treatment of acute and chronic pain by the application of specific pain-managing ulRFE fields, another expression of EMulate’s Therapeutic ...
Manufactured by:Medprin Biotech GmbH based inFrankfurt, GERMANY
100% absorbable within 7-14 days. Hemostasis in capillary, venous as well as small artery bleeding. StypCel™ works when ligation or other conventional methods are impracticable or ...
by:Sorrento Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
Sorrento utilizes a proprietary knock-out knock-in (KOKI) technology to modify normal healthy donor derived T cells to genetically engineer them to express the dimeric antigen receptor into T-cell receptor (TCR) alpha chain constant region (TRAC). In this manner, TRAC is knocked out and antigen is knocked into its locus. The Dimeric Antigen Receptor (DAR) utilizes a Fab instead of the scFv ...
Manufactured by:NeuroMD based inNorth Miami Beach, FLORIDA (USA)
The most advanced, FDA-cleared system to restore your lower back health and provide lasting pain relief. Equipped with pre-set, clinically studied NMES parameters, the Corrective Therapy Device® delivers proven electrical stimulation to correct the source of the pain. Get started on the path to relief during our biggest sale ever with savings of $200 and enjoy a 60-day at-home ...
Manufactured by:BioCydex based inPoitiers, FRANCE
Vectisol® is dedicated to the preservation of organs, tissues and cells. This molecular complex limits the deleterious effects of the ischemia-reperfusion ...
Manufactured by:Elpiscience based inShanghai, CHINA
LAG3 is an immune checkpoint receptor known to suppress T cell activation. We designed ES005 to block LAG3 ligands, including MHC class II and FGL1. Through unique epitope binding, ES005 is able to recognize human LAG3 with high affinity. In preclinical studies, ES005 inhibited tumor growth both as a monotherapy and in combination with a PD-1 ...
by:XELTIS BV based inEindhoven, NETHERLANDS
The aXess graft is a restorative, synthetic, electrospun blood vessel for arteriovenous hemodialyisis access, overtime turning into a living vessel made of patient’s own ...
Manufactured by:ZIND Verfahrenstechnik based inMainz, GERMANY
At pilot stage, the primary membrane candidate has been chosen, as process parameters. Typically at this stage, the production method is being verified and production materials produced for toxicology or pre-clinical trials and predictable scalability is imperative. In order to facilitate the manufacturing life cycle of a successful therapeutic candidate, cGMP manufacturing needs to begin at ...
Manufactured by:MR Solutions based inGuildford, UNITED KINGDOM
The MRS*PET INSERT, designed by MR Solutions, facilitates simultaneous PET/MR imaging, enabling the acquisition of multi-parametric information from the same subject with precision. Built to integrate seamlessly with cryogen-free MR systems up to 9.4 Tesla, it offers flexibility in research settings due to its removable nature. This product can function independently of the MR system, effectively ...
by:Verb Biotics based inBoston, MASSACHUSETTS (USA)
Yso2 is a preclinical program targeting Crohn’s disease. It aims to develop Christensenella gut bacteria as a safe, efficient and groundbreaking oral biotherapy. YSOPIA has identified a lead candidate to relieve Crohn’s disease associated symptoms and slow down disease progression. Discover the articles we published in Scientific Reports: Relizani et al. 2022 and Kropp et al. 2021. ...
Manufactured by:AstraZeneca based inCambridge, UNITED KINGDOM
IVX-121 targets respiratory syncytial virus (RSV), a major cause of viral pneumonia for which no vaccine has been FDA approved. IVX-121 incorporates a stabilized prefusion F antigen licensed from NIAID/NIH (DS-Cav1; Science 2019). RSV F is known to undergo major structural changes that allow viral entry into the host cell, and during that process, critical protective epitopes are lost. Protein ...