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Moditope Prostatic Equipment & Supplies In Denmark
2 equipment items found
Manufactured by:Scancell based inOxford, UNITED KINGDOM
All mesenchymal tumours such as endometrial, renal, sarcomas, lymphomas and lung tumours express vimentin as their major cytoskeletal protein and are potential targets for a modified vimentin vaccine. In addition, many epithelial tumours, such as breast, ovarian, gastrointestinal and prostate switch from expression of cytokeratin to vimentin during metastasis in a process known ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
The Modi-2 vaccine exploits a second post-translational modification, stimulating the production of CD4 T cells using tumour-associated peptide epitopes in which the lysine residues are converted to homocitrulline. This change occurs via a process known as carbamylation, leading to a change in molecular charge which, in turn, alters antigenic properties and can result in the generation of unique ...