Refine by
Tumor Suppression Equipment & Supplies
94 equipment items found
Manufactured by:Elicio Therapeutics based inBoston, MASSACHUSETTS (USA)
ELI-008 is a multivalent lymph node–targeted AMP peptide vaccine developed to target p53 hotspot mutations. p53 is a tumor-suppressing protein that controls the cell cycle, DNA replication, and uncontrolled cell division during tumor growth.4 Mutations in the p53 protein lead to uncontrolled tumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
NHWD-870 is a potent, orally active and selective BET family bromodomain inhibitor and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Oroxin B (OB) possesses obvious inhibitory effect and induces early apoptosis rather than late apoptosis on liver cancer cells through upregulation of PTEN, down regulation of COX-2, VEGF, PI3K, and p-AKT[1].Oroxin B (OB) selectively induces tumor-suppressive ER stress in malignant lymphoma ...
Manufactured by:Elpiscience based inShanghai, CHINA
SIRPα is an inhibitory receptor expressed only on myeloid cells and dendritic cells. Binding of CD47 to SIRPα delivers a “don’t eat me” signal to suppress phagocytosis. Tumor cells frequently overexpress CD47 to evade macrophage-mediated destruction. To overcome this issue, ES004 stimulates potent macrophage-mediated phagocytosis ...
by:Alfa Cytology based inU.S. VIRGIN ISLANDS
The P12FR2 aptamer sodium inhibits PAUF-induced migration of PANC-1 (human pancreatic cancer cells) in a wound healing assay and suppresses tumor growth in a mouse CFPAC-1 pancreatic cancer ...
by:Carina Biotech based inMawson Lakes, AUSTRALIA
Advanced colorectal cancer currently has a poor prognosis and is the deadliest form of cancer for Australians 25 to 34 years old. LGR5 is a cancer stem cell marker that is highly expressed on advanced colorectal cancer and other cancers. In colon cancer patients, LGR5+ expression has been correlated with a particularly poor ...
Manufactured by:Carbon Medical Technologies, Inc. based inSt. Paul, MINNESOTA (USA)
Bright imaging characteristics make this marker easy to identify through dense tissue. This marker has the attributes of gold with the benefit of the biocompatible ...
Manufactured by:Carbon Medical Technologies, Inc. based inSt. Paul, MINNESOTA (USA)
This enhanced marker is designed for customers who use MRI for treatment planning. BiomarC Enh enjoys all the same benefits as our legacy BiomarC, while providing a superior reference for MRI image fusion. This marker is designed for soft tissue localization using kV ...
Manufactured by:Carbon Medical Technologies, Inc. based inSt. Paul, MINNESOTA (USA)
Uniquely designed for the special needs of a proton center; the BiomarC PRO fiducial marker is manufactured to minimize artifact and perturbation. It is designed for soft tissue localization using kV ...
Manufactured by:Carbon Medical Technologies, Inc. based inSt. Paul, MINNESOTA (USA)
Breast Tissue Markers used in conjunction with Breast Biopsy. Many medical conditions, including all cases of cancer, must be diagnosed by removing a sample of tissue from the patient and sending it to a pathologist for examination. This procedure is called a biopsy. ...
Manufactured by:Carbon Medical Technologies, Inc. based inSt. Paul, MINNESOTA (USA)
BiomarC EX provides excellent visibility for both kV and MV imaging. This marker is manufactured with a slightly denser core material allowing for enhanced daily images. This marker can be especially helpful on larger patients or patients with bony or implant interference with treatment ...
Manufactured by:Carbon Medical Technologies, Inc. based inSt. Paul, MINNESOTA (USA)
Feel confident with the reliable placement of “BiomarC Secure.” The industry’s only ceramic fiducial marker now has the ability to be sutured to soft tissue. The precise nature of a marker sutured to the affected tissue allows for the ultimate benefit in precision radiation ...
by:Starpharma Holdings Limited based inMelbourne, AUSTRALIA
DEP® cabazitaxel is an enhanced version of leading prostate cancer drug cabazitaxel (Jevtana®). Cabazitaxel (Jevtana®) had global sales of €536M in 2020 despite having multiple US FDA “Black Box” warnings. ...
Manufactured by:Carbon Medical Technologies, Inc. based inSt. Paul, MINNESOTA (USA)
BiomarC, our legacy marker, is an implantable fiducial marker. It provides an extremely valuable method to ensure accurate and repeatable target positioning in radiation therapy with little perturbation of the radiation beam. This exclusive marker is manufactured with our least dense nonmetallic material. It is designed for soft tissue localization using kV imaging or ...
Manufactured by:Brooklyn ImmunoTherapeutics (BTX) based inSan Diego, CALIFORNIA (USA)
Why human derived? Brooklyn has developed a powerful method to create complex cytokine mixtures derived from a human source. Cytokines are powerful immune factors that play an essential role in T cell signaling, activation, proliferation, and tumor-fighting responses. We know cytokines may induce beneficial reactions in cancer patients. To date, available cytokine therapies have been recombinant ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Bispecific T cell engaging receptors (TCER®) are off-the-shelf biologics that leverage the body’s immune system by redirecting and activating T cells towards cancer cells expressing specific tumor targets. The design of these novel biologics allows any T cell in the body to become activated and attack the tumor, regardless of the T cells’ intrinsic ...
Manufactured by:Senti Biosciences based inSouth San Francisco, CALIFORNIA (USA)
Senti Bio has established, and continues to scale, a powerful Design-Build-Test-Learn development engine to generate our therapeutic gene circuits. Unique to Senti Bio’s approach is the speed, quantity and quality of the multiple types of gene circuits designed, resulting in thousands of gene circuits engineered to date. Senti Bio believes that this approach to programming gene circuits is ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1α inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TP-472 is a selective BRD9/7 inhibitor, with Kds of 33 nM and 340 nM for BRD9 and BRD7, respectively. TP-472 exhibits >30-fold selectivity for BRD9 over other bromodomain family members except BRD7[1][2]. TP-472 induces apoptosis of melanoma ...