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Cytokine Production Equipment Supplied In Asia Middle East
5 equipment items found
Manufactured by:Elpiscience based inShanghai, CHINA
Typically for TNF receptor family members, 3 molecules of OX40 bind to the trimeric OX40 ligand-protein, activating downstream NF-κB, PI3K, and AKT pathways, which lead to increased cytokine production. Activation of OX40 enhances T-cell expansion, differentiation, and the generation of memory T-cells. OX40 antibodies have been clinically tested to expand ...
Manufactured by:Mesoblast Ltd. based inMelbourne, AUSTRALIA
Remestemcel-L is being developed for inflammatory diseases in children and adults including the treatment of acute graft versus host disease (aGVHD), a potentially life-threatening complication of an allogeneic bone marrow transplant (BMT). Currently, there are no products currently approved in the United States for treatment of steroid-refractory aGVHD in children under 12, and off-label options ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES014 is a first-in-class anti-CD39xTGF-β bispecific antibody (bsAb) that simultaneously targets the adenosine and TGF-β pathways, two major immunosuppressive mechanisms in the tumor microenvironment (TME). Solid tumors frequently express TGF-β, which suppresses T cell activation and induces CD39 expression, the rate-limiting enzyme in the ATP-adenosine pathway. The anti-CD39 ...
Manufactured by:RedHill Biopharma Ltd. based inTel-Aviv, ISRAEL
Opaganib (ABC294640) is a first-in-class, proprietary sphingosine kinase-2 (SK2) selective inhibitor, administered orally, with anticancer, anti-inflammatory and anti-viral ...
Manufactured by:Mesoblast Ltd. based inMelbourne, AUSTRALIA
MPC-300-IV is being developed for the treatment of diabetic complications, including diabetic kidney disease known as diabetic ...