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T Cell Equipment Supplied In Asia Middle East
45 equipment items found
Manufactured by:Takeda Pharmaceutical Company Limited based inChuo-ku, JAPAN
Adaptate Biotherapeutics is focussed on therapeutic antibodies which harness the potential of patients’ own gamma delta T cells in situ. Gamma delta T cells play a critical role in immune surveillance, recognising malignant/transformed cells through a pattern of stress markers and exerting potent ...
Manufactured by:Eutilex Co.,Ltd. based inSeoul, SOUTH KOREA
Fully humanized anti-human 4-1BB monoclonal antibody. Agonistic effect of EU101 promotes cytotoxic T lymphocyte response and it leads to eradication of ...
Manufactured by:PharmAbcine Inc. based inYuseong-gu, SOUTH KOREA
PMC-309 is an engineered monoclonal antibody that targets the negative immune checkpoint human VISTA (V-domain Ig suppressor of T cell activation). It indirectly promotes T cells' immune responses by inhibiting VISTA-expressing immunosuppressive cells such as MDSCs (Myeloid-Derived Suppressor ...
Manufactured by:PharmAbcine Inc. based inYuseong-gu, SOUTH KOREA
PMC-402 is a monoclonal antibody that targets the human TIE2 that regulated activation, proliferation, and repolarization of Tie2 expressing macrophages, resulting in T cell activation. It binds to TIE2 expressing macrophages that activate T cells in the tumor microenvironment ...
Manufactured by:Elpiscience based inShanghai, CHINA
OX40, also known as CD134, is a member of the tumor necrosis factor (TNF) receptor family and is an important co-stimulator of T cell responses. Typically for TNF receptor family members, 3 molecules of OX40 bind to the trimeric OX40 ligand-protein, activating downstream NF-κB, PI3K, and AKT pathways, which lead to increased cytokine production. Activation ...
Manufactured by:Beijing Challen Biotechnology Co., Ltd. based inDaxing District, CHINA
Scope of application: Detect the expression of CD8 in human biological specimens and provide doctors with auxiliary information for diagnosis. Testable items: Lymphocyte subpopulation detection, regulatory T cells, PD-1, expressed in most large granular lymphocytic leukemia (LGL), and also expressed in a small number of T cell ...
Manufactured by:Takeda Pharmaceutical Company Limited based inChuo-ku, JAPAN
Brentuximab vedotin (brand name: Adcetris) is a treatment for post-transplant consolidation, relapsed or refractory Hodgkin lymphoma (cancer of the lymphatic system distinguished by the presence of CD30-positive Reed-Sternberg cells), and systemic anaplastic large cell lymphoma (a type of aggressive T-cell ...
Manufactured by:Beijing Challen Biotechnology Co., Ltd. based inDaxing District, CHINA
Scope of application: Detect the expression of CD4 in human biological specimens and provide doctors with auxiliary information for diagnosis. Testable items: Lymphocyte subpopulation detection, CD4 cell count, regulatory T cells, PD-1, blast cells of acute T lymphoblastic leukemia, tumor cells ...
by:GI Innovation based inSeoul, SOUTH KOREA
Promotes the generation of cancer-specific effector T cell (Teff) in lymph nodes, and induces the activation and proliferation of tumor-infiltrating Teff and NK cells. Controls the immuno-suppressive function of regulatory T cells (Tregs) in tumor microenvironment (TME). Restores T ...
Manufactured by:Elpiscience based inShanghai, CHINA
LAG3 is an immune checkpoint receptor known to suppress T cell activation. We designed ES005 to block LAG3 ligands, including MHC class II and FGL1. Through unique epitope binding, ES005 is able to recognize human LAG3 with high affinity. In preclinical studies, ES005 inhibited tumor growth both as a monotherapy and in combination with a PD-1 ...
Manufactured by:Beijing Challen Biotechnology Co., Ltd. based inDaxing District, CHINA
Scope of application: Detect the expression of CD3 in human biological specimens and provide doctors with auxiliary information for diagnosis. Testable items: detection of lymphocyte subpopulations, regulatory T cells, PD-1, expressed in blast cells of acute T-ceii leukemia and tumor cells of mature ...
Manufactured by:EirGenix, Inc based inNew Taipei City, TAIWAN
CRM197 can be used as a carrier protein for vaccine delivery. It acts by helping polysaccharide antigens to bind on and be internalized into antigen-presenting cells. This in turn induces T-cell-dependent responses. ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES101 is a first-in-class tetravalent bispecific antibody targeting 4-1BB and PD-L1. It has a unique mechanism of action as 4-1BB activation is dependent on PD-L1 binding. 4-1BB is a T cell co-stimulatory receptor and is a compelling immune checkpoint target. 4-1BB targeting antibodies being developed by multinational companies have exhibited dose-dependent ...
Manufactured by:Shenzhen Landwind Medical Co., Ltd based inShenzhen, CHINA
When the human body contacts with foreign antigens, the first antibody produced is IgM, which is secreted directly by the receptor on the surface of B cells. The B cells that produce IgM enter the lymph nodes, receive stimulation from T cells and antigen-presenting cells in the center of occurrence, further ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES014 is a first-in-class anti-CD39xTGF-β bispecific antibody (bsAb) that simultaneously targets the adenosine and TGF-β pathways, two major immunosuppressive mechanisms in the tumor microenvironment (TME). Solid tumors frequently express TGF-β, which suppresses T cell activation and induces CD39 expression, the rate-limiting enzyme in the ...
Manufactured by:Promega Corporation based inMadison, WISCONSIN (USA)
The antibodies used to stimulate T cell activation via interaction with co-stimulatory receptors on the effector cells can be cross-linked via binding to FcγRIIb receptors on CHO-K1 cells. Based on the properties of the antibody tested, the Co-Stimulatory Immune Checkpoint (i.e., OX40, CD40, GITR and 4-1BB) bioassays can ...
Manufactured by:Hybio Pharmaceutical Co., Ltd. based inGuangdong, CHINA
1 mg: Hasten T cell differentiation,reinforce immune function of tumor patients; Boost NK cell cytoactivity,two-ways regulation of immune function in case of active hepatitis; Contain virus replication,treat chroic Hepatitis B; Used both in IV drop and intramuscular injection. 10 mg: Particlarly indicated for adjuvant therapy of malignant ...
Manufactured by:VBI Vaccines Inc. based inCambridge, MASSACHUSETTS (USA)
Because of their structural similarity to viruses presented in nature, including their particulate nature and repetitive structure, virus-like particles (VLPs) are ideal for stimulating potent immune responses. VLPs can be customized to present any protein antigen, including multiple antibody and T cell targets, making them ideal technologies for the development ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
Epitope is a part of an antigenic protein consisting of a sequence of 8 to 15 amino acids that provide the immunogenicity of an antigen protein. Immune receptors such as TCR, BCR, and MHC of various immune cells including T cells, B cells, and macrophages recognize epitopes and lead to various immune responses. As a simple ...
Manufactured by:Promega Corporation based inMadison, WISCONSIN (USA)
4-1BB (CD137/TNFRSF9), a member of the tumor necrosis factor receptor superfamily, is an inducible co-stimulatory receptor expressed on T cells, natural killer (NK) cells and innate immune cell populations. When present on the cell surface, 4-1BB interacts with 4-1BB ligand (4-1BBL) and induces subsequent ...