- Home
- Equipment
- australasia
- epitopes
Refine by
Epitopes Equipment Supplied In Australasia
6 equipment items found
Manufactured by:AROTEC Diagnostics Limited based inWellington, NEW ZEALAND
Autoantibodies staining the nuclei or the perinuclear zone of neutrophils by indirect immunofluorescence are referred to as pANCA whereas those giving a clear cytoplasmic fluorescence are referred to as cANCA. The antigen recognised by most cANCA sera has been identified as proteinase 3 (also known as myeloblastin, p29 or ...
Manufactured by:AROTEC Diagnostics Limited based inWellington, NEW ZEALAND
tTG is the most widely distributed member of the transglutaminase family, being expressed in almost all cell types. Belonging to a family of calcium dependent enzymes it has been found to be expressed in up to 8 different isoforms, depending on its loci within tissues. Enzymatically tTG is known to play a role in tissue repair, specifically in remodelling functions whilst also exhibiting ...
Manufactured by:AROTEC Diagnostics Limited based inWellington, NEW ZEALAND
Autoantibodies to centromeric proteins in the sera of patients with scleroderma were first described in 1980. Subsequent studies confirmed that anti-centromere antibodies (ACA) were most often found in patients with a limited form of systemic sclerosis previously referred to as CREST syndrome. These autoantibodies are also often detected in sera from patients with Raynaud’s phenomenon and ...
Manufactured by:AROTEC Diagnostics Limited based inWellington, NEW ZEALAND
Autoantibodies staining the nuclei or the perinuclear zone of neutrophils by indirect immunofluorescence are referred to as pANCA whereas those giving a clear cytoplasmic fluorescence are referred to as cANCA. The antigen recognised by most pANCA sera has been identified as ...
Manufactured by:Biosceptre International Limited based inCambridge, UNITED KINGDOM
nfP2X7 is a tumour-specific form of the P2X7 ligand-gated ion channel, consisting of three identical protein subunits. When exposed to high concentrations of extracellular adenosine triphosphate (ATP), P2X7 forms a channel, driving a range of diverse physiological functions including proliferation and immune cell functions. Under prolonged stimulation, P2X7 can form a membrane pore that’s ...
Manufactured by:AROTEC Diagnostics Limited based inWellington, NEW ZEALAND
The existence of autoantibodies to bactericidal/permeability-increasing protein (BPI) was first described when it was noticed that 11 of 51 sera that were cANCA positive in immunofluorescence, recognised a 57 kDa antimicrobial cationic protein known as CAP57 in both ELISA and Western blot. It is now known that CAP57 and BPI are ...