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Solid Tumor Equipment Supplied In China
9 equipment items found
Manufactured by:Shanghai Henlius Biotech, Inc based inShanghai, CHINA
(serplulimab injection, anti-PD-1 mAb), company’s first self-developed innovative monoclonal antibody, was approved by the NMPA for the treatment of Microsatellite Instability-High (MSI-H) solid tumors in March 2022, providing an alternative treatment option for patients with MSI-H solid tumors. Henlius actively promotes ...
Manufactured by:Elpiscience based inShanghai, CHINA
The SIRPα antibody blocks the “don’t-eat-me” signal while the TAA antibody provides an “eat-me” signal through Fc receptor engagement. ES028 and the BiME platform are designed for potent activation of phagocytosis and directly kill tumor cells for treatment of solid tumors. We expect to develop ES028 as a ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES014 is a first-in-class anti-CD39xTGF-β bispecific antibody (bsAb) that simultaneously targets the adenosine and TGF-β pathways, two major immunosuppressive mechanisms in the tumor microenvironment (TME). Solid tumors frequently express TGF-β, which suppresses T cell activation and induces CD39 expression, the rate-limiting ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES104 is a bispecific antibody that simultaneously blocks Delta-like ligand 4/Notch (DLL4) and vascular endothelial growth factor A (VEGF-A) signaling pathways, which are critical to angiogenesis and tumor vascularization. VEGF also plays an important role in creating an immune suppressive TME. Pre-clinical and early clinical data of ES104 show that blocking both pathways ...
Manufactured by:Shanghai Henlius Biotech, Inc based inShanghai, CHINA
HLX07, recombinant anti-epidermal growth factor receptor (EGFR) humanised monoclonal antibody injection independently researched and developed as biobetter. It was granted IND approvals to be evaluated in clinical trials in China and the United States. It demonstrated favorable safety and tolerability profile in a prospective, open-label, dose-escalation Phase 1 clinical study (HLX07FIH, ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:NTRK1, NTRK2 and NTRK3 gene fusion detection. Detection Significance:Guiding the selection of NTRK ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection of 56 cancer-related genes, including 3000 COSMIC mutation loci. Guiding individualized diagnosis and treatment of pan-cancera ...
Manufactured by:Amoy Diagnostics Co., Ltd. based inXiamen, CHINA
Neurotrophic tropomyosin-related kinase (NTRK) is a group of high affinity nerve growth factor (NGF) receptors, including tropomyosin receptor kinases (Trk) A, B, and C which are encoded by NTRK1, NTRK2, and NTRK3 genes, respectively. NTRK proteins, upon NGF ligand binding, function in the phosphorylation of members of the RAS/MAPK, PI3K/AKT, PLC-y pathways that play a key role in cell ...
Manufactured by:Sartorius AG based inGoettingen, GERMANY
Innovation is at the heart of everything we do. Our proprietary drug delivery technology platform, Veltis®, uses engineered recombinant albumin to enhance albumin’s intrinsic characteristics for optimal therapeutic performance of your ...