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Drug Metabolism Equipment Supplied In Europe
12 equipment items found
Manufactured by:ViennaLab Diagnostics GmbH based inVienna, AUSTRIA
Genetic variants of the drug-metabolizing enzyme CYP2C9 lead to high inter-individual dose response variability of certain drugs, in particular coumarin-based anticoagulants. The CYP2C9 mpx RealFast™ Assay allows for the simultaneous detection of CYP2C9*2 and CYP2C9*3 variants exhibiting impaired enzyme ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. "Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, ...
Manufactured by:Ahlstrom based inEspoo, FINLAND
Easy Collection - Reliable and Quantitative Analysis - Design for Automation. Ahlstrom AutoCollect card is designed for dried blood spot (DBS) microvolume sampling, transport and storage at ambient ...
Manufactured by:Allevi, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
Clinically relevant drug-drug interactions (DDI) are a serious concern for any new drug development project. To better support capturing the multiple mechanisms of DDI potential using primary hepatocytes, we now offer Interaction Qualified Human Hepatocytes (Catalog HUCPI) which are characterized for 3 major mechanisms of DDI: transporter activity, enzyme activity, and induction potential, ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Acquisition of hepatocyte samples is now a critical step for research activities. The limited availability of human hepatocytes makes cryopreservation a good option to provide researchers with a sufficient amount of viable liver ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic stellate cells (HSC) are also known as perisinusoidal cells and they are located in the space of disses. These cells are the major cell type involved in liver fibrosis in response to liver injury and they play a key role in the homeostasis of liver extracellular matrix, repair, regeneration and fibrosis, and control retinol metabolism, storage and ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
The fresh human hepatocytes we offer are obtained and isolated from human donors for research purposes. These cells are a superior in-vitro model because they thrive in an environment closely resembling the in-vivo host ...
Manufactured by:Quay Pharma based inFlintshire, UNITED KINGDOM
Lipophilic systems have proven effectiveness in improving bioavailability by helping drugs to overcome problems like poor gastric solubilisation, degradation and elimination due to first-pass metabolism in the liver, other types of pre-systemic metabolism, and drug transport and efflux effects. At Quay Pharma, we are highly ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Primary animal hepatocytes and subcellular liver fractions (Microsomes, Cytosol and S9 fraction) are model systems often used for a variety of in vitro screenings and analyses prior to clinical studies in human and animal health as well as environmental toxicology. Hepatocytes in suspension are preferable for short-term studies whereas plated hepatocytes are more useful for long-term ...
Manufactured by:Technopath Clinical Diagnostics based inBallina, IRELAND
Increase laboratory efficiencies - Reduce handling time, reclaim storage space, reduce lot evaluation time, reduce packaging waste, reduce dead-volume waste with Multichem IA Plus - consolidated Third Party immunoassay QC ...
by:Oncodesign based inDijon, FRANCE
Oncodesign’s Pharmimage® technology module is a pharmaco-imaging module designed to monitor the effect of treatments and to define effective translational biomarkers in precision medicine. It includes translational, optical (bioluminescence, fluorescence), functional and molecular (MRI, PET, SPECT, CT scanner, MRI/PET coupling) multi-modal imaging capabilities, adapted to small rodents ...
Manufactured by:Owlstone Medical Ltd. based inCambridge, UNITED KINGDOM
The measurement of the volatile organic compounds (VOCs) produced by the body's metabolic activity is a powerful approach for health monitoring and disease detection. Volatile organic compounds (VOCs) are gaseous molecules that can be sampled quickly and non-invasively from breath with Breath Biopsy®. They can originate either from within the body (endogenous VOCs) or from ...