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Immune Activity Equipment Supplied In Europe
20 equipment items found
Manufactured by:OSE Immunotherapeutics based inNantes, FRANCE
A humanized monoclonal antibody, is an antagonist of the alpha chain of the interleukine-7 receptor, CD127, present on T effector cells, thus down regulating the immune activity. Interleukin-7 (IL-7) is a cytokine that controls the proliferation, apoptosis and activation of CD4 and CD8 effector T-cells in ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Assessment of immune activation: Alcyomics has a wide range of cell phenotypic services for your research needs, to benefit both drug discovery and validation. With our in-house state-of-the-art instrumentation, we can analyse and deliver accurate analyses of T-cell proliferation responses and perform multiplex cytokine analysis. This screening test can be used ...
by:Stemline Therapeutics, Inc. based inNew York, NEW YORK (USA)
SL-701 is an immunotherapy designed to direct the immune system to attack targets present on certain malignancies including brain cancer. SL-701 comprises 3 short synthetic peptides that correspond to epitopes of targets including IL-13Rα2, EphA2, and survivin; 2 of these synthetic peptides (IL-13Rα2 and survivin) are mutant and believed to enhance ...
Manufactured by:multimmune GmbH based inMunich, GERMANY
ENKASTIM is based on the activation of immune cells called natural killer (NK) cells that are major players in the body's first line of defense, also called innate immunity. The immune effector cells are activated ex vivo (outside the body; ENKASTIM-ev) or in vivo (inside the body; ...
Manufactured by:Novavax based inGaithersburg, MARYLAND (USA)
In 5 separate studies, carried out in collaboration with the National Institute of Allergy and Infectious Diseases, active immunization with the Ebola GP vaccine was shown to be highly immunogenic and efficacious in preventing lethal disease in non-human primates challenged with EBOV. Our 2015 Phase 1 clinical trial demonstrated that our Ebola GP vaccine is ...
Manufactured by:Virometix AG based inSchlieren, SWITZERLAND
Effective antigen delivery and a strong and durable response is the basis for successful cancer vaccines. The SVLP approach, with its modular and flexible design, the inherent adjuvant properties and other immune system activators, lends itself to the development of particle-based vaccines against cancer: SVLPs displaying cancer antigens are optimally presented ...
by:Hookipa Pharma Inc. based inVienna, AUSTRIA
Our scientific platform includes two distinct approaches to arenavirus-based therapies: replicating and non-replicating. Our replicating technology is designed to create a stronger immune response that we believe is more appropriate for use in oncology. Our non-replicating technology is designed to evoke a potent immune response for prophylactic use against infectious disease. ...
by:Fusix Biotech based inMünchen, GERMANY
This results in an oncolytic virus platform with an excellent safety profile and effective replication kinetics. Tumor-selective replication leads to significant oncolytic activity, while fusion-based cell death adds to its potent immune-stimulatory properties. Together this results in tumor regression and systemic tumor-specific immunity. ...
Manufactured by:OncoVITA based inParis, FRANCE
Oncovita’s MeasovirTM proprietary platform relies on a DNA plasmid vector that expresses a modified measles Schwarz virus antigenome able to generate recombinant viruses by using a clonal reverse genetics system. This versatile plug-and-play platform allows producing new viruses expressing very large amounts of additional genetic ...
Manufactured by:OncoVITA based inParis, FRANCE
Engineered viruses have proven to be powerful “bullets” to target cancer cells and to promote their immunogenic death. Oncolytic viruses are replicative viruses that preferentially infect tumor cells while preserving healthy cells. Some of them, in particular the measles virus, exhibit immuno-adjuvant properties that reinforce the antitumor immune response by breaking immune tolerance ...
by:T3 Pharmaceuticals AG based inBasel, SWITZERLAND
T3 Pharma has developed a proprietary cancer therapy platform based on regulating and harnessing the natural behaviours of live bacteria. The genetically engineered bacteria selectively target solid tumors, where they deliver chosen protein payloads into the ...
Manufactured by:Roche Diagnostics International AG based inRotkreuz, SWITZERLAND
Immunoassay for the qualitative detection of total antibodies against HAV. Elecsys® Anti-HAV II is an immunoassay for the in vitro qualitative detection of total (IgM and IgG) antibodies to HAV in human serum and plasma. It is used as an aid to detect a past or existing HAV infection or to determine the presence of antibody response to HAV in vaccine recipients.11 ...
Manufactured by:Elthera AG based inSchlieren, SWITZERLAND
L1 cell adhesion molecule (L1CAM) is a cell surface protein which is aberrantly expressed in many different tumor types including pancreatic, ovarian, breast, lung, and colorectal cancer. L1CAM expression increases the malignancy of these tumors by promoting cellular proliferation, metastatic spread, tumor angiogenesis, and resistance to chemotherapy. Accordingly, L1CAM-positive tumors ...
Manufactured by:terraplasma medical GmbH based inGarching near Munich, GERMANY
In addition, there is the healing effect: CAP therapy has an antipruritic effect and promotes cell regeneration (cell division) of healthy skin cells by activating local immune processes. The treatment is valued as ...
Manufactured by:Perrery Farmaceutici S.r.l. based inPescantina (VR), ITALY
IMMUNOVIS is a natural product for restoring and maintaining immunity, strengthening the protective properties of the body through the normalization of microflora, as well as for complex rehabilitation after infections, intoxications, injuries and ...
by:MSD Animal Health based inMilton Keynes, UNITED KINGDOM
An opaque fluid vaccine containing formalin killed cells expressing iron regulated antigens from the epidemiologically most important serotypes of Pasteurella haemolytica and Pasteurella trehalosi in buffered physiological saline and adsorbed onto aluminium hydroxide. Thiomersal is included as a preservative. For the active immunisation of sheep as an aid in the control of pasteurellosis caused ...
Manufactured by:CanVirex AG based inBasel, SWITZERLAND
Oncolytic measles viruses as a multiplexed immune-modulating platform for cancer therapy. Cancer remains a medical and social burden worldwide despite several technological advances in the past decades. Conventional cancer treatments such as surgery, chemo-, or radiotherapy are restricted to local therapy or by dose-limiting toxicities and may induce drug resistance during treatment. In recent ...
Manufactured by:OSE Immunotherapeutics based inNantes, FRANCE
Tedopi®, OSE Immunotherapeutics’s most advanced product and therapeutic neo-epitope-based vaccine, is a proprietary combination of nine optimized neo-epitopes, selected and optimized from 5 tumoral antigens to activate specifically T cells, plus one epitope giving universal helper T cell response targeting T cell ...
by:Pure Biologics SA based inWroclaw, POLAND
Triple-negative breast cancer (TNBC) is a highly proliferative, rapidly growing, and aggressive form of cancer. TNBC can be further categorized into three types: Type 1 (also known as the “cold” type) is characterized by a tumor with low infiltration of immune cells into the tumor microenvironment; Type 2 is characterized by inactive cells of the innate immune system; Type 3 (also ...
by:Pure Biologics SA based inWroclaw, POLAND
In cancer, a balance between immune system effector and regulatory cells becomes disturbed. Regulatory T cells inhibit the activity of effector cells, including NK cells, a process known as immunosuppression. The PB003 (PureActivator) project embraces a novel approach, aiming to develop a drug based on a bimodal fusion protein, which synergistically ...