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Pharmacokinetic Equipment Supplied In Europe
39 equipment items found
Manufactured by:Arcomed AG based inKloten, SWITZERLAND
A new propofol pharmacokinetic-pharmacodynamic (PKePD) model was developed using bispectral index (BIS) as the targeted endpoint based on previously published data from 30 ...
by:Italfarmaco SpA based inMilan, ITALY
Nimedex (nimesulide in ß-cyclodextrin granules of 400 mg for oral suspension) combines the treatment benefits of the active ingredient nimesulide with the pharmacokinetic advantages of ß-cyclodextrin. The innovative formulation of Nimedex facilitates its solubilization, anticipates the absorption of the active ingredient and provides a quicker analgesic effect ...
Manufactured by:VECT-HORUS based inMARSEILLE, FRANCE
VECTrans® is based on the specific design and optimization of ‘molecular vectors’ that, once conjugated to a payload, enable its delivery to target cells in the body. In other words, Vect-Horus’ core expertise relies on modifying pharmacokinetic (PK) and distribution profile of therapeutic or imaging candidates. ...
Manufactured by:Mablink Bioscience based inLyon, FRANCE
Antibody–drug conjugates (ADCs) are a unique class of targeted immuno-oncology therapeutics that combine the tumor-targeting selectivity, stability, and favorable pharmacokinetic profile of monoclonal antibodies, with the potent antitumor activity of cytotoxic drugs. The ultimate goal of ADCs is to increase the therapeutic index of potent chemical agents, by the selective ...
by:Horizon Therapeutics plc based inSaint Kevin`s, IRELAND
A monoclonal antibody against insulin-like growth factor-1 receptor (IGF-1R). TED in Japan (OPTIC-J): Phase 3 randomized, placebo-controlled trial in Japan to evaluate TEPEZZA in patients with moderate-to-severe active ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
The PhysioMimix™ MPS-TL6 plate enables organ to organ crosstalk for multi-organ studies. The MPS-TL6 plate enables true 2-organ communication between a Transwell® and a Liver compartment in 6 independent wells, both with their own circular flow. Each Transwell compartment accommodates standard 24-well plate 0.33 cm2 Transwell® inserts. Each liver compartment contains an embedded ...
Manufactured by:Mablink Bioscience based inLyon, FRANCE
Most of the challenges of ADCs are linked to the hydrophobicity of the cytotoxic drugs used, which degrade the pharmacological properties of the antibody when attached to ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. "Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, ...
Manufactured by:InSilicoTrials Technologies based inStafford, VIRGINIA (USA)
PCa GnRH Agonists Simulator enables simulations of clinical trials on a virtual population of prostate cancer patients being treated with a GnRH agonist ...
Manufactured by:Ahlstrom based inEspoo, FINLAND
Easy Collection - Reliable and Quantitative Analysis - Design for Automation. Ahlstrom AutoCollect card is designed for dried blood spot (DBS) microvolume sampling, transport and storage at ambient ...
Manufactured by:InSilicoTrials Technologies based inStafford, VIRGINIA (USA)
A tool that performs in silico clinical trials to assess the neutropenic effects of a chemotherapeutic agent in a virtual population of cancer patients ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic stellate cells (HSC) are also known as perisinusoidal cells and they are located in the space of disses. These cells are the major cell type involved in liver fibrosis in response to liver injury and they play a key role in the homeostasis of liver extracellular matrix, repair, regeneration and fibrosis, and control retinol metabolism, storage and ...
Manufactured by:Araris Biotech AG based inAu, Zurich, SWITZERLAND
Araris Biotech AG, a spin-off company from the Paul Scherrer Institute (PSI) and ETH Zurich, is pioneering the development of a novel, proprietary antibody-drug conjugate (ADC)-linker technology. Our linker platform enables payload attachment to ‘off-the-shelf’ antibodies in one step without needing to re-engineer or reduce antibodies, resulting in highly homogenous, stable and potent ...
Manufactured by:Surmodics, Inc. based inEden Prairie, MINNESOTA (USA)
The Surmodics drug-delivery coatings utilize innovative technology to meet a variety of clinical needs – from short-term to long-term controlled release – and across a range of compounds including small molecules and antibiotics. Our unique Bravo™ durable drug-delivery polymer system is designed for site-specific delivery and stability of low molecular weight ...
Manufactured by:Gyros Protein Technologies AB based inUppsala, SWEDEN
Gyrolab® xPand immunoassay system is packed with essential functions requested by users wanting greater flexibility, higher throughput, unattended operation and rapid analysis of large sample numbers. Analyze up to five CDs unattended – generate up to 560 data points within five hours. Cooling of samples and reagents. Mix and match methods/CDs in a single run. Flexible run setup & ...
by:Pureims B.V. based inRoden, NETHERLANDS
Amikacin Cyclops™ is an amikacin dry powder inhaler for the treatment of tuberculosis (TB). Inhaled amikacin from the Cyclops™ will result in higher amikacin concentrations in the lungs than conventional infusion or intramuscular injection. This could more rapidly decrease contagiousness by sterilizing the upper airways of patients with ’open’ (smear positive) TB, ...
Manufactured by:Benevolent based inLondon, UNITED KINGDOM
Advancing a potent and selective Atopic Dermatitis treatment through the clinic. What is Atopic Dermatitis? Atopic Dermatitis (AD), the most common type of eczema, is a chronic relapsing inflammatory skin disease that results in itchy, red, swollen, and cracked skin. Our work : BEN-2293, a Pan-Trk antagonist, is being developed to treat AD without the need to use topical steroids and designed to ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Our Non-Alcoholic Fatty Liver Disorder (NAFLD)/NASH in vitro Services offer a preclinical tool to test therapeutics in a human-relevant model, replicating key disease phenotypes including fibrosis and reporting clinical biomarkers to allow translatability to clinical trials. ...
Manufactured by:InStar Technologies a.s. based inLiberec, CZECH REPUBLIC
Cebedix & Cebidix-h are an Oral Thin Films using our InStripTM technology with CBD (Canabidiol). InStrip technology allows you to use the full potential of the substances contained in Cebedix, in this case CBD. You will achieve the desired effect from a much smaller dose. And a smaller dose means a smaller toll on the organism. The first effects of Cebedix in the form of a thin, ...
Manufactured by:Gyros Protein Technologies AB based inUppsala, SWEDEN
The Gyrolab xPlore system gives your team the agility to develop immunoassays more quickly and increase data quality with minimal hands-on time. Reliable and precise walkaway automated immunoassays accelerate every phase of biotherapeutic product development. Utilizes proprietary Gyrolab CDs. Generates up to 112 high-quality data points per CD within an hour. Samples are processed in parallel. ...