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Antigen Expression Equipment Supplied In Germany
4 equipment items found
Manufactured by:ORYX GmbH & Co. KG based inBaldham, GERMANY
The human cyclin-dependent kinase inhibitor p16INK4a is a tumor antigen expressed in various cancers, including lung and breast cancer. In normal cells, p16INK4a is rarely expressed and leads to immediate senescence. In all cancers associated with high risk human papilloma virus (HR-HPV), p16INK4a is constantly expressed as an ...
Manufactured by:ORYX GmbH & Co. KG based inBaldham, GERMANY
Several cancers arise from the lack of DNA mismatch repair (MMR) resulting in the accumulation of thousands of single deletions or insertions at coding microsatellites (MSI-H). These mutations lead to the inactivation of specific proteins and to the expression of frameshift peptides (FSPs). These FSPs are tumor-specific antigens, which are constantly ...
Manufactured by:Affimed GmbH based inHeidelberg, GERMANY
AFM24, an EGFR-directed ICE® (innate cell engager) molecule, represents a distinctive mechanism that engages innate immune cells by recruiting NK cells and macrophages to the site of the tumor for effective and efficient tumor-cell killing. Potential to treat various solid tumor types with a more acceptable safety profile while remaining immune to the challenge of ...
Manufactured by:Toleris Biotherapeutics GmbH based inWürzburg, GERMANY
AIM Bio has developed a platform of Autoimmunity Modifying Biologicals (AIM Biologicals) that uses soluble, near-physiological proteins to induce selective, antigen-specific immune tolerance. These proteins mimic a natural process observed in pregnancy that protects the embryo from the maternal immune system. By leveraging optimized soluble versions of the non-classical MHC Ib molecule HLA-G, AIM ...