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Cancer Associated Cells Equipment Supplied In Germany
32 equipment items found
Manufactured by:Cfm Oskar Tropitzsch GmbH based inMarktredwitz, GERMANY
17-DMAP-GA belongs to the Geldanamycin family. It is an HSP90 inhibitor. 17-DMAP-GA was shown to be a powerful inhibitor of cancer cell growth (IC50 below 100 nm). Its binding affinity to HSP90 was not significantly affected compated to Geldanamycin and other analogs while its water solubility was highly improved compated to 17-AAG. Reference: ZQ Tian et al. Bioorg. Med. Chem 2004 ...
Manufactured by:Cfm Oskar Tropitzsch GmbH based inMarktredwitz, GERMANY
17-AEP-GA belongs to the Geldanamycin family. It is an HSP90 inhibitor. 17-AEP-GA was shown to be a powerful inhibitor of cancer cell growth (IC50 below 100 nm). Its binding affinity to HSP90 was not significantly affected compated to Geldanamycin and other analogs while its water solubility was highly improved compated to 17-AAG. Reference: ZQ Tian et al. Bioorg. Med. Chem 2004 ...
Manufactured by:Santa Cruz Biotechnology, Inc. based inDallas, TEXAS (USA)
Pladienolide B is a highly potent splicing inhibitor of both hypoxia signals and cancer cell ...
by:Fusix Biotech based inMünchen, GERMANY
As multi-mechanistic antitumor agents, oncolytic viruses are emerging to be potent immunotherapeutic treatment options in different tumor indications. Oncoytic viruses specifically replicate in tumor cells due to altered signalling pathways supporting the tumor’s immune esape, leaving open replication advantages for viruses susceptible to intact signaling pathways. ...
Manufactured by:Nanion Technologies GmbH based inMunich, GERMANY
The CardioExcyte 96 is a hybrid system recording both contractility and electrophysiology of intact cardiomyocyte networks. In addition, the base impedance readout is continuously and automatically monitored as a measure of acute and chronic cell activity. No subtleties of cytotoxic responses are missed, this includes non-contractile cell types such as hepatocyte-like cells or cancer cells as ...
Manufactured by:Cerca Biotech based inBerlin, GERMANY
The progesterone receptor (PGR) also belongs to the gene family of steroid receptors. Upon binding of progesterone, the receptor is activated and modifies expression of several downstream genes. Estrogen and progesterone receptors are found in Breast Cancer cells that depend on estrogen and related hormones (such as progesterone) to grow. All patients with invasive Breast Cancer or a Breast ...
Manufactured by:Affimed GmbH based inHeidelberg, GERMANY
The proprietary ROCK platform enables a tumor-targeted approach that can be tailored across hematological and solid tumors. The ROCK (Redirected Optimized Cell Killing) platform allows for a modular approach to generating customizable ICE (innate cell engager) molecules. High-affinity ICE (innate cell engager) molecules, which are created using the ROCK platform, are capable of bivalent NK-cell ...
Manufactured by:Santa Cruz Biotechnology, Inc. based inDallas, TEXAS (USA)
Bafilomycin A1® is a macrolide antibiotic and potent and selective inhibitor of vacuolar-type H+ ATPase ...
Manufactured by:Santa Cruz Biotechnology, Inc. based inDallas, TEXAS (USA)
Pheophorbide a is a chlorophyll-related compound studied for its anti-tumor and anti-cancer ...
Manufactured by:multimmune GmbH based inMunich, GERMANY
mi-APO is a targeted protein product with potential to be used for the treatment of most tumor types. The product targets surface-bound heat shock protein 70 (Hsp70). Surface-bound Hsp70 is a tumor-specific marker expressed on about 50-75% of various cancer entities, e.g. lung, colon, breast, pancreas. Application of mi-APO, a recombinant serine protease, results in a specific ...
Manufactured by:Sequana Medical NV based inSint-Denijs Westrem, BELGIUM
Ascites is also a common complication of certain late-stage cancers due to fluid build-up in the peritoneal cavity from a number of causes including draining of the lymph system. While life expectancy for many cancer patients with malignant ascites is short (less than 3 months), ovarian and breast cancer patients often have longer life expectancies. In 2018, the incidence in the U.S. and EU5 is ...
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
In collaboration with the bioinformatics firm 4HF Biotech GmbH which is a bioinformatics firm specializing in cancer data mining to discover new anti-cancer drugs, we offer data mining for analysis of the genetic signature of tumor cell lines that are sensitive for a customer drug to reveal potential biomarkers. The Biomarker Analysis is based on the sensitivity profile of the customer compound ...
Manufactured by:3B Pharmaceuticals GmbH based inBerlin, GERMANY
Radiopharmaceuticals are unique medicinal formulations containing radioisotopes which are used in major clinical areas for diagnosis and/or therapy. Targeted radiopharmaceuticals bind to specific structures such as proteins or cells within the body and thus accumulate in particular places, such as e.g. tumor lesions in a cancer ...
by:Fusix Biotech based inMünchen, GERMANY
The FUSIX Technology relies on a fusion-based oncolytic virus platform. Below you can see FUB101 in action. In this timelapse video FUB101 is killing a monolayer of cancer cells (HCC) within 48 hours through a fusogenic mechanism of action. The FUSIX technology is based on a hybrid virus construct combining all the advantages of both parental platforms while minimizing risks factors. This ...
Manufactured by:Epigenomics AG based inBerlin, GERMANY
Colorectal cancer is curable in about 90% of cases if detected early. Nevertheless, this disease is one of the most frequent causes of cancer-related deaths in the industrialized world. Regular screening can prevent colorectal cancer. Epi proColon® offers a convenient way of detecting colorectal cancer: in blood. It’s as simple as a blood draw. The test is performed by a clinical ...
Manufactured by:Genekam Biotechnology AG based inDuisburg, GERMANY
Human circulating tumour cells (CTC) in blood are an important indicator of the progression of a cancer and in some cases, these may be an indication of so called sleeping tumour cells i.e. it does mean that there is an active disease. Therefore PCR tests are being conducted in many laboratories around the world for presence of markers of such blood cells. As the number of such cell is very low, ...
Manufactured by:Genekam Biotechnology AG based inDuisburg, GERMANY
Isolation of circulating tumour cell kit with two markers and PCR Kit for Biomarkers of Melanoma from CTC. Human circulating tumour cells (CTC) in blood are an important indicator of the progression of a cancer and in some cases, these may be an indication of so called sleeping tumour cells i.e. it does mean that there is an active disease. Therefore PCR tests are being conducted in many ...
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
Tulmimetostat is a second-generation EZH2 inhibitor that has been designed to achieve comprehensive target coverage through extended on-target residence time. EZH2 acts as an epigenetic writer and normally places one or more methyl groups on a histone protein, leading to the suppression of gene expression. Some cancers depend on an abnormal pattern of gene expression and re-direct EZH2 to genes ...
Manufactured by:multimmune GmbH based inMunich, GERMANY
The company´s proprietary platform technology is based on the discovery of a novel tumor-specific marker - a membrane-expressed form of heat shock protein 70 (Hsp70). Membrane Hsp70 is most frequently expressed on a variety of different tumor types including lung, colon, breast, head and neck, stomach, pancreas carcinomas, malignant melanoma, and hematological diseases, but never on the ...
Manufactured by:Affimed GmbH based inHeidelberg, GERMANY
AFM24, an EGFR-directed ICE® (innate cell engager) molecule, represents a distinctive mechanism that engages innate immune cells by recruiting NK cells and macrophages to the site of the tumor for effective and efficient tumor-cell killing. Potential to treat various solid tumor types with a more acceptable safety profile while remaining immune to the challenge of ...