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Preclinical Animal Models Equipment Supplied In Netherlands
5 equipment items found
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
Tulmimetostat is a second-generation EZH2 inhibitor that has been designed to achieve comprehensive target coverage through extended on-target residence time. EZH2 acts as an epigenetic writer and normally places one or more methyl groups on a histone protein, leading to the suppression of gene expression. Some cancers depend on an abnormal pattern of gene expression and re-direct EZH2 to genes ...
by:veriNOS pharmaceuticals GmbH based in, NETHERLANDS
Ronopterin is an allosteric inhibitor of inducible NO synthase (iNOS) that rapidly decreases the excessive production of NO resulting from acute overactivation of this enzyme. Ronopterin has no significant effect on the physiological production of NO by other constitutive NO-synthesizing enzymes that are essential for brain and body ...
Manufactured by:LAVA Therapeutics N.V. based inUtrecht, NETHERLANDS
Our lead program, LAVA-051, is a unique, humanized gamma-delta bsTCE targeting CD1d-expressing tumors, including multiple myeloma, chronic lymphocytic leukemia (CLL), and acute myeloid leukemia (AML). We have achieved preclinical proof-of-concept with LAVA-051 by demonstrating efficacy and safety in a variety of preclinical models. LAVA-051 uniquely activates both Vγ9Vδ2 T cells as ...
Manufactured by:Fibralign Corporation based inUnion City, CALIFORNIA (USA)
Fibralign is developing a pipeline of compelling novel products which are based on its proprietary Nanoweave® scaffolding platform that can be tailored to address a wide range of high-value applications. Nanoweave technology provides the means to precisely print 3D scaffolding in such a way that mimics human tissue nano structure and directly influence the body’s repair ...
Manufactured by:DSM based inHeerlen, NETHERLANDS
Discover our implantable drug delivery systems made of bioresorbable polymers that release precise quantities of therapeutic agents gradually over time. DSM is a global leader in biomedical materials science – experience that we are now using to create advanced sustained release drug products as implantable or injectable delivery forms. DSM offers two proprietary, highly versatile polymer ...