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Cell Based Assay Equipment Supplied In North America
28 equipment items found
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Sword scientists specialize in the development of qualitative or quantitative bioanalytical methods that measure cellular biomolecules active in a specific disease state. Cell-based assays are bioanalytical methods that measure the presence, amount, or activity of biomolecules in cells, cell fractions, nuclear ...
Manufactured by:Aurora Biomed Inc. based inVancouver, BRITISH COLUMBIA (CANADA)
Cell-based assays have always been a powerful tool in biological research laboratories. Recently, cell-based assays have become preferred over traditional biochemical assays by both the pharmaceutical and biotech industry because they provide a more in vivo-like environment for ...
Manufactured by:Cell Biolabs, Inc. based inSan Diego, CALIFORNIA (USA)
Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Sword scientists will use our cell-based assay development expertise to develop a customized method to corroborate the binding specificity of your antibody-drug conjugate (ADC). Our understanding of the molecular basis of cellular growth, proliferation, and differentiation is continually evolving as the genes, proteins, and biochemical pathways ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular ...
Manufactured by:Stem Pharm, Inc based inMadison, WISCONSIN (USA)
Stem Pharm’s technologies are based on functionalized multi-arm polyethylene glycol monomers that incorporate bioactive peptides to modulate adhesion and biomechanical properties. Our optimized substrates generate appropriate cellular environments that improve outcomes for cell expansion, differentiation, and in vitro ...
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Puracyp’s nuclear receptor activation kits are all-inclusive cell-based assay systems. The kits incorporate mycoplasm-free, stably-transfected cells derived from hepatoma cell lines that have been treated with a cell-arrest agent to prevent further proliferation. Exposure to the ...
Manufactured by:Molecular Devices, LLC. based inSan Jose, CALIFORNIA (USA)
The ImageXpress® Pico Automated Cell Imaging System is more than a digital microscope, combining high-resolution imaging with powerful analysis. Whether running fluorescence imaging or brightfield assays, the automated imager features a comprehensive portfolio of preconfigured protocols for cell-based assays ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth ...
Manufactured by:Resonant Sensors Incorporated (RSI) based inArlington, TEXAS (USA)
Guided-mode resonance (GMR) technology is a novel label-free optical approach that can measure a wide variety of molecular interactions in real-time using a standard microarray plate format. GMR signal(s) response is directly related to the binding density of the medium on the sensor surface. ...
Manufactured by:Shifa Biomedical Corporation based inMalvern, PENNSYLVANIA (USA)
LDLR is a cell-surface receptor that binds LDL-C and carries it into cells to the endosome for degradation and thus reduces the plasma level of LDL-C (Figure 1). However, PCSK9 controls the degradation of the LDLR in the liver (Figure 1) and thereby contributes to cholesterol ...
Manufactured by:LI-COR Biotech, LLC based inLincoln, NEBRASKA (USA)
The Odyssey DLx Imaging System is a 2-channel near-infrared (NIR) fluorescent imager capable of producing high-quality Western blots, multi-well plate assays, tissue section images, and more. As an effective, high-throughput imager, the Odyssey DLx Imager takes exceptional, unsaturated images in a single acquisition without sacrificing image fidelity. Identical optical settings are used for every ...
Manufactured by:InterTech Development Company based inSkokie, ILLINOIS (USA)
Proven InterTech Microscale Technology measures leaks down to the equivalent of a 0.5 micron defect diameter. A careful review of application requirements including the Maximum Allowable Leakage Limit (MALL) will dictate the test method used. Testing is consistent with ASTM requirements (F-3287-17, F-2338-09). Proprietary technology is available for testing with minimal headspace volumes. ...
Manufactured by:Promega Corporation based inMadison, WISCONSIN (USA)
4-1BB (CD137/TNFRSF9), a member of the tumor necrosis factor receptor superfamily, is an inducible co-stimulatory receptor expressed on T cells, natural killer (NK) cells and innate immune cell populations. When present on the cell surface, 4-1BB interacts with 4-1BB ligand (4-1BBL) and induces subsequent cell proliferation and production of interferon gamma (IFNγ) and interleukin-2 (IL-2), ...
Manufactured by:Angany Inc. based inSt-Jean, QUEBEC (CANADA)
We aim to provide safe, dependable and lasting relief from allergy. We have developed a unique therapeutic approach based on a proprietary allergy vaccine technology to address the specific challenge of allergy (eBioparticle-Potentiated ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TCJL37 is a potent, selective, and orally bioavailable TYK2 inhibitor with a Ki of 1.6 nM. TCJL37 can be used for the research of inflammatory bowel diseases ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 can also be used for the research of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Tamnorzatinib (ONO-7475) is a potent, selective, and orally active Axl/Mer inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. Tamnorzatinib sensitizes AXL-overexpressing EGFR-mutant NSCLC cells to the EGFR-TKIs, suppresses the emergence and maintenance of tolerant cells. Tamnorzatinib combines with Osimertinib (HY-15772) provides a bright promise for the study of EGFR-mutated ...