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Genetic Mutation Equipment Supplied In North America
7 equipment items found
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
CRISPR/Cas9 genome editing can make permanent, precisely targeted changes in patients’ chromosomes and repair the underlying genetic mutation, whereas more traditional gene therapy typically involves introducing a non-permanent copy of a gene into patients’ cells. These attributes of CRISPR/Cas9 provide a significant therapeutic edge over other gene ...
Manufactured by:KORU Medical Systems based inMahwah, NEW JERSEY (USA)
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic, life-threatening blood disorder characterized by the complement-mediated destruction (hemolysis) of oxygen-carrying red blood cells. The disease is caused by a genetic mutation in the DNA and causes red blood cells to be missing a critical protein responsible for protecting them. Hemolysis occurs in ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Protein misfolding is the root of many diseases, including lysosomal storage disorders and neurodegenerative ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
OncoPeptTUME — A novel in-silico approach to model the tumor microenvironment and predict treatment efficacy and long-term survival benefits for immunotherapy applications. Cancer immunotherapy is now established as a major therapeutic modality. Cancer immunotherapy drugs elicit their anti-tumor immune response in a subset of the treated patients by activating CD8 T-cells and provide ...
by:Tesis Biosciences based inScottsdale, ARIZONA (USA)
CGx Testing is a preventative gene test that looks for specific inherited changes (mutations) in a person’s genetic make-up. Harmful mutations may increase a persons’ chance, or risk, of developing a disease such as cancer. These conditions are considered hereditary. Appropriate genetic testing may be used to ...
Manufactured by:Scopus BioPharma based inNew York, NEW YORK (USA)
Our licensed gene therapy, CO-sTiRNA™, is a dual-action STAT3 inhibitor. STAT3 is a gene that drives tumor cell growth and anti-tumor immune suppression. CO-sTiRNA™ is a highly selective and targeted gene therapy that silences the activity of the STAT3 gene by way of RNA interference. CO-sTiRNA™ also stimulates TLR9 receptors to activate the body’s immune defense to ...
Manufactured by:Elicio Therapeutics based inBoston, MASSACHUSETTS (USA)
Our lymph node-targeted mKRAS cancer vaccine; Our Amphiphile (AMP)-powered lead candidate, ELI-002, generates a robust immune response against mutant Kristen rat sarcoma (mKRAS), with the potential to offer patients a stronger fight against the most aggressive cancers. Preliminary data have shown that ELI-002 produces a potent mKRAS-specific T-cell response, including both CD4+ and CD8+ ...
