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In Vivo Study Equipment Supplied In North America
69 equipment items found
Manufactured by:Cabaletta Bio, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
Precision Approach to Address the Underlying Cause of Disease: Our second candidate, MuSK-CAART, is designed to treat myasthenia gravis (MG), an autoimmune disease affecting the neuromuscular junction that can lead to motor impairment, muscle weakness, and respiratory ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
A combination therapy consisting of PKC agonists with or without HDAC inhibitors, designed to reactivate latent HIV reservoirs so that HIV can be eliminated by antiviral therapy and eradicated from the body. HIV Latency: Although highly active antiretroviral therapy (HAART) is undoubtedly a lifesaving therapy for millions of AIDS patients, the persistence of latent HIV-infected cellular ...
Manufactured by:CELLINK based inBoston, MASSACHUSETTS (USA)
PCL provides a reinforcing structure to load-bearing tissue constructs, including bone grafts and osteochondral plugs developed for in vitro and in vivo studies. It can also provide a temporary scaffold for overhanging ...
Manufactured by:Symple Surgical Inc. based inFlagstaff, ARIZONA (USA)
Figure 1 shows Computer Generated Thermal Simulation data of the DirectAblate Renal Denervation SystemTM. Figure 2 is histological sample of an in vivo study performed with the DirectAblate Renal Denervation SystemTM. The treatment zone is nearly identical in size and shape to the computer based modeling as identified with NBT viability staining (blue/purple ...
Manufactured by:Synergy Biomedical, LLC based inWayne, PENNSYLVANIA (USA)
Data Driven Performance - In Vivo Study Results; Bioactive glass has typically been used in a particulate form consisting of irregular particles and a broad size range (32-710 um). Instead of creating a bone graft with these "off-the-shelf" particles, Synergy utilized a unique spherical particle shape and conducted an in vivo optimization ...
Manufactured by:BriaCell Therapeutics Corp. based inWest Vancouver, BRITISH COLUMBIA (CANADA)
BriaCell’s novel, proprietary PKCδ inhibitors have shown activity against multiple RAS transformed tumors. This target has an attractive safety profile based on in vivo studies and knock out mouse studies. PKCδ also has potential activity as an immunotherapeutic by blocking TGFβ signaling. PKCδ inhibitors are ...
Manufactured by:FUJIFILM VisualSonics, Inc. based inToronto, ONTARIO (CANADA)
With a powerful combination of high frame rates and advanced image processing, the Vevo 3100 micro-ultrasound imaging system reduces speckle noise and artifacts while preserving and enhancing critical information for small animal in vivo ...
Manufactured by:Labeo Technologies Inc. based inMontreal, QUEBEC (CANADA)
The Fiber Photometry System by Labeo Technologies Inc. is designed for comprehensive in vivo studies of brain activity in freely moving rodents, including mice and rats. It provides precise measurements essential for neuroscience research, accommodating various applications such as imaging calcium indicators and utilizing FRET for high sensitivity in ratiometric ...
Manufactured by:SynVivo, Inc. based inHuntsville, ALABAMA (USA)
The SynRAM™ 3D Inflammation Model from SynVivo was developed to study the entire inflammation pathway in a dynamic environment. The SynVivo platform delivers a physiologically realistic model (including flow and shear) and enables real-time tracking of rolling, adhesion, and migration processes. The model recreates a histological slice of co-cultured tissue and/or tumor ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize contraction-relaxation cycles of the cardiomyocytes. Cardiomyocytes may be used in various in vitro or in vivo studies; transplantation into normal or diseased systems; cardiac toxicology studies; or cardiovascular developmental ...
Manufactured by:Boston Pharmaceuticals based inCambridge, MASSACHUSETTS (USA)
BOS-228 is a novel monobactam for infections caused by multidrug-resistant carbapenem-resistant ...
Manufactured by:AnaSpec based inFremont, CALIFORNIA (USA)
Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and ...
Manufactured by:Imbed Biosciences based inMiddleton, WISCONSIN (USA)
Chronic, nonhealing wounds of varying types are treated with Microlyte® Matrix. Learn more about its use and effectiveness. Engineered to naturally contour to the underlying wound ...
Manufactured by:FUJIFILM VisualSonics, Inc. based inToronto, ONTARIO (CANADA)
The Vevo® 3100 LT Imaging System is FUJIFILM VisualSonics’ entry-level micro-ultrasound product. It is perfectly suited for performing basic preclinical studies while meeting both your research and budgetary needs. The Vevo 3100 LT offers real-time, in vivo physiological information that contributes to understanding biological functions and so much ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
APH-0912 is a combination of a Taxotere® prodrug and monoclonal antibody targeted to treat metastatic cancer. The prodrug is a combination of a docetaxel molecule, the potent anticancer drug, and a sugar molecule to enhance solubility covalently linked to a tumor-specific antibody. This molecular combination is not bioactive prior to administration. After infusion and adsorption onto targeted ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
An alpha (α)-secretase modulator for ameliorating Alzheimer’s Disease pathophysiology and cognitive impairment with neuroprotection. Aphios is developing APH-1104, a more potent analog of Bryostatin-1, which is neuroprotective by α-secretase activation via novel PKC isoforms, down-regulation of pro-inflammatory and angiogenic processes and the substitution of β-amyloid for ...
Manufactured by:Imbed Biosciences based inMiddleton, WISCONSIN (USA)
Microbial contamination is a threat to healing of all surgical wounds. Learn more about how Microlyte Surgical can assist in the protection of surgical sites. Microlyte® Surgical provides you with a new antimicrobial tool for management of surgical wounds. Created for surgeons – by surgeons. The world’s first and only fully-synthetic, antimicrobial, and bioresorbable matrix ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
Poor Solubility and Associated Formulation and Bioavailability Difficulties. Although paclitaxel is an effective anticancer drug, its solubility is low (~ 0.4 µg/mL), which limits its medical utility to intravenous applications. Docetaxel (Taxotere®) was developed as a paclitaxel derivative having improved water solubility; its solubility, however, is only ~ 14 µg/mL. Several ...
Manufactured by:Scopus BioPharma based inNew York, NEW YORK (USA)
We are developing MRI-1867, our licensed rationally designed, orally available, dual-action, hybrid, small molecule that is an inverse agonist of the CB1 receptor, as well as an inhibitor of the iNOS ...
Manufactured by:NuLiv Science based inBrea, CALIFORNIA (USA)
InnoSlim® is a pharmaceutical-grade glucose and lipid metabolic regulator through activation of the adiponectin and AMPK signaling ...