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Ipsc Equipment Supplied In North America
52 equipment items found
Manufactured by:Vascugen Inc. based inMadison, WISCONSIN (USA)
Development of complex iPSC-based therapeutics benefits from an engineering mindset. Each layer of the development and manufacturing process is considered part of the ‘Full Stack’ that leads to finished product. An integrated stepwise approach improves the probability of arriving at the right therapeutic candidate and reduces downstream risks to manufacturing and ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
Cardiomyocytes are cardiac muscle cells. They are terminally differentiated and facilitate contractile forces (“beatings”) of the heart. Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize contraction-relaxation cycles of the cardiomyocytes. Cardiomyocytes may be used in various in vitro or in vivo studies; ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
They have been implicated in many human neurodegenerative disorders such as multiple sclerosis, amyotrophic lateral sclerosis (ALS), Alzheimer’s disorder, Huntington’s disease and Parkinson’s disease. Tempo’s iAstro™: human iPSC-derived astrocytes are derived from integration-free induced pluripotent stem cell (iPSC) lines under a ...
Manufactured by:Khloris Biosciences, Inc. based inMountain View, CALIFORNIA (USA)
By developing cardiomyocytes directly from patient-derived iPSCs, we create a non-invasive, personalized platform to directly observe the effects of drug therapies on heart ...
Manufactured by:Khloris Biosciences, Inc. based inMountain View, CALIFORNIA (USA)
Khloris' iPSCs are optimized to generate high-functioning cardiomyocytes, enabling development of an allogeneic source of donor cells for patients with damaged heart ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
Blood Brain Barrier (BBB) is an important feature of the cerebral vasculature. Cells that form the barrier are called Brain Microvascular Endothelial Cells (BMECs). The barrier regulates the transport of molecular chemicals (including metabolites) and cells between the brain and blood. The barrier’s functionality is conducted via specialized groups of tight junction proteins and ...
Manufactured by:Advanced Instruments based inNorwood, MASSACHUSETTS (USA)
MatriClone is a new matrix designed to support iPSC growth in single seeding workflows while maintaining pluripotency. MatriClone is optimized for ‘in-solution’ seeding and optically suited for automated imaging. When used as part of the VIPS seeding protocol, MatriClone offers high levels of single cell survival and subsequent outgrowth, all in a simple, automated ...
Manufactured by:BrainXell based inMadison, WISCONSIN (USA)
Origin: Human iPSC line, 2M Viable Cells/Vial (BX-0200), Contents: 1 vial of cells and corresponding BrainXell, supplements, Cryopreserved. ...
Manufactured by:StemBioSys, Inc. based inSan Antonio, TEXAS (USA)
CELLvo™ Matrix Plus is the next generation of CELLvo™ Matrix technology. CELLvo™ matrices are the only substrates that aim to recapitulate biochemical as well as structural and mechanical cues of the native niche by leaving the extracellular matrix intact. Cell-derived matrices create a biologically-relevant culture environment for a variety of cell types by providing ...
Manufactured by:Brooklyn ImmunoTherapeutics (BTX) based inSan Diego, CALIFORNIA (USA)
Cellular reprogramming refers to the process of transforming patient skin cells into pluripotent stem cells, called induced pluripotent stem cells (iPSC). Since 2012 Nobel Prize Winner Dr. Shinya Yamanaka's initial discovery of iPSC in 2006, iPSC availability has transformed the field of cell therapy. Brooklyn uses the fastest, ...
Manufactured by:Trailhead Biosystems Inc. based inBeachwood, OHIO (USA)
We are developing these specialized human cells from human (non-embryo) induced pluripotent stem cells (iPSCs) using our proprietary HD-DOE™ research and development platform. We already have a nascent protocol for the generation of hypothalamic NPY-expressing cells. We believe that the delivery of specific subsets of hypothalamic cells from iPSC would be a ...
Manufactured by:BrainXell based inMadison, WISCONSIN (USA)
Origin: Human iPSC line. Products: 2M Viable Cells/Vial - Standard (BX-0600). 1M Viable Cells/Vial - Standard (BX-0600e). Contents: 1 vial of cells and corresponding BrainXell supplement. ...
Manufactured by:Trailhead Biosystems Inc. based inBeachwood, OHIO (USA)
We are developing human red blood cells (Erythrocytes) from induced pluripotent stem cells (iPSCs) in a two-step process (iPSCs to HSCs and HSCs to Erythrocytes). Our novel protocols will use small molecules to make red blood cells, which will allow production of red blood cells at scale. We will use our red blood cells as the foundation for a cell therapy for ...
Manufactured by:BrainXell based inMadison, WISCONSIN (USA)
Origin: Human iPSC line. Products: 2M Viable Cells/Vial - Standard (BX-0650). 1M Viable Cells/Vial - Standard (BX-0650e). Contents: 1 vial of cells and corresponding BrainXell supplement. ...
Manufactured by:Brooklyn ImmunoTherapeutics (BTX) based inSan Diego, CALIFORNIA (USA)
However, adult-tissue-derived MSC have shown inconsistent therapeutic efficacy, significant variability among samples, and limited proliferative capacity. On the other hand, MSC derived from iPSCs (iMSC) offer a near limitless supply of cells due to their superior expansion potential. Our data shows improved therapeutic properties and greater consistency of iMSC relative to ...
Manufactured by:Trailhead Biosystems Inc. based inBeachwood, OHIO (USA)
We are currently developing a novel protocol that will use only small molecules to make human cortical interneurons of the forebrain from induced pluripotent stem cells (iPSCs). Our dopaminergic neurons can be used to accelerate the drug discovery process for treatments of neuropsychiatric disorders, schizophrenia, autism, and intellectual ...
Manufactured by:Trailhead Biosystems Inc. based inBeachwood, OHIO (USA)
We are developing human platelets (Megakaryocytes) from human (non-embryo) induced pluripotent stem cells (iPSCs) in a two-step process (iPSCs to HSCs and HSCs to Megakaryocytes). Our novel protocols will use small molecules to make platelets, which will allow production of platelets at scale. We will use our platelets as the foundation for a cell therapy for the ...
Manufactured by:Brooklyn ImmunoTherapeutics (BTX) based inSan Diego, CALIFORNIA (USA)
Utilizing highly efficient mRNA-based gene editing, Brooklyn will precisely engineer changes in the genome of iPSC, followed by a thorough characterization of the new cell line. The gene-edited iPSC will then be used to produce iMSC that have been endowed with beneficial properties to broaden and enhance therapeutic uses. Our first gene-edited iMSC product ...
Manufactured by:Sartorius CellGenix GmbH based inFreiburg, GERMANY
CellGenix Recombinant Human Activin A reliably promotes definitive endoderm differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). It in addition maintains the undifferentiated state of ESCs and iPSCs. CellGenix® rh Activin A is produced in our dedicated animal-free facility ensuring maximum safety for optimal use in ATMP ...
Manufactured by:Khloris Biosciences, Inc. based inMountain View, CALIFORNIA (USA)
iPSC vaccination presents a differentiated approach to cancer treatment, targeting a panoply of antigens, leveraging the patient's immune system for optimized antigen presentation, and engaging both cellular and humoral ...