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Pharmacokinetic Equipment Supplied In North America
396 equipment items found
Manufactured by:Regeneron Pharmaceuticals Inc. based inTarrytown, NEW YORK (USA)
Veloci-Bi allows for the generation of full-length bispecific antibodies similar to native antibodies that are amenable to production by standard antibody manufacturing techniques and likely to have favorable antibody-like pharmacokinetic properties. ...
Manufactured by:Vitalis, LLC based inNew York, NEW YORK (USA)
Aspirin is one of the oldest, most complex drugs in medicine, with many different indications and applications. It has unique pharmacokinetic properties where its metabolites effect aspirin itself, depending on the rates of metabolism in different parts of the ...
Manufactured by:Tasso, Inc. based inSeattle, WASHINGTON (USA)
The Tasso-M20 device delivers whole dried blood samples from the patient to the lab. It can be used for PK (pharmacokinetic) monitoring in patients enrolled in clinical trials. Subjects can successfully collect volumetrically precise samples regardless of access to trial sites. The Tasso-M20 is CE marked and FDA ...
Manufactured by:Mersana Therapeutics based inCambridge, MASSACHUSETTS (USA)
Instead of direct conjugation to an antibody, drug molecules are attached through an optimized, cleavable linker to the Fleximer scaffold, which is then conjugated to the antibody through a non-cleavable linker. Fleximer dramatically improves drug solubility, pharmacokinetics, and immunogenicity, and significantly increases the number of drug molecules carried by each ...
Manufactured by:BiomX based inNess Ziona, ISRAEL
Phase 1b/2a clinical study in CF patients is composed of two parts. Results from Part 1 aimed to evaluate the safety, pharmacokinetics, and microbiologic/clinical activity are expected in Q3 of 2022. Results from Part 2 aimed to demonstrate safety and efficacy are expected by Q1 of 2023. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
mTOR inhibitor-3 is a remarkably selective mTOR inhibitor with a Ki of 1.5 nM. mTOR inhibitor-3 suppresses mTORC1 and mTORC2 in cellular and in vivo pharmacokinetic (PK)/pharmacodynamic (PD) ...
Manufactured by:BiomX based inNess Ziona, ISRAEL
Although different organs are affected in IBD and PSC (gut in IBD and liver in PSC) the two diseases are thought to be related since approximately 70% of PSC patients also suffer from IBD. Results from a pharmacokinetic and safety Phase 1a study demonstrated safety and tolerability with successful delivery of a high concentration of viable phage to the lower gastrointestinal ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GSK620 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Enpatoran can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran exhibits excellent pharmacokinetic properties in vivo. Enpatoran can be used for both innate and adaptive autoimmunity blocking research ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer ...
Manufactured by:Mersana Therapeutics based inCambridge, MASSACHUSETTS (USA)
Dolasynthen retains the favorable properties of Dolaflexin, including our proprietary DolaLock technology for a controlled bystander effect, with even better physicochemical and pharmacokinetic ...
Manufactured by:Lumencor based inBeaverton, OREGON (USA)
The VOLTA Scanner is particularly significant for drug discovery applications, allowing comprehensive characterization of pharmacokinetics and ion-channel interactions under various ...
Manufactured by:Laxxon Medical based inNew York, NEW YORK (USA)
Laxxon Medical's SPID Technology, also known as Screen Printed Innovative Drug Technology, utilizes advanced additive manufacturing to revolutionize drug delivery systems (DDSs). This patented approach enhances the pharmacokinetic profiles of pharmaceuticals by employing sophisticated geometric internal structures alongside a strategic distribution of active ingredients. Central ...
by:Sutro Biopharma Inc. based inSouth San Francisco, CALIFORNIA (USA)
Sutro’s cell-free expression technology provides a rapid and powerful platform for the discovery and development of antibodies that bind simultaneously to two separate antigens (bispecific ...
Manufactured by:Pfizer Inc. based in, NEW YORK (USA)
ALDACTAZIDE oral tablets contain: spironolactone 25 mg, hydrochlorothiazide 25 mg or spironolactone 50 mg, hydrochlorothiazide 50 ...
Manufactured by:InSilicoTrials Technologies based inStafford, VIRGINIA (USA)
PCa GnRH Agonists Simulator enables simulations of clinical trials on a virtual population of prostate cancer patients being treated with a GnRH agonist ...
Manufactured by:Ahlstrom based inEspoo, FINLAND
Easy Collection - Reliable and Quantitative Analysis - Design for Automation. Ahlstrom AutoCollect card is designed for dried blood spot (DBS) microvolume sampling, transport and storage at ambient ...
by:Zymeworks Inc based inVancouver, BRITISH COLUMBIA (CANADA)
with a modular suite of proprietary cytotoxins (cell-killing compounds), stable linkers, and conjugation technologies. A broader window of opportunity. Deliver potent cell-killing compounds specifically to diseased target cells with optimal safety and efficacy. ZymeLink™, a next-generation antibody drug conjugate (ADC) platform, is a suite of proprietary cytotoxins (cell-killing compounds), ...
Manufactured by:InSilicoTrials Technologies based inStafford, VIRGINIA (USA)
A tool that performs in silico clinical trials to assess the neutropenic effects of a chemotherapeutic agent in a virtual population of cancer patients ...
Manufactured by:Cingulate based inKansas City, KANSAS (USA)
CTx-1301 utilizes a breakthrough multi-core formulation of dexmethylphenidate, a compound approved by the FDA for the treatment of ...