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Biotherapeutics Equipment Supplied In Switzerland
11 equipment items found
Manufactured by:MV BioTherapeutics SA based inBellinzona, SWITZERLAND
The ApyraMed technology exploits a recombinant live biotherapeutic that promotes adaptive intestinal homeostasis. In cancer patients, it enhances immune system competence, whereas in dysbiosis safeguards the intestinal ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
Create biological architectures with sound. Sound Induced Morphogenesis (SIM) is a gentle, fast, and easy method to generate multi-cellular, spatially orchestrated tissue constructs using sound waves. This versatile method addresses necessities in the broad field of life sciences, finding application in tissue engineering, regenerative medicine, or pharmaceutical research for drug ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
Biologicals – Cells, spheroids, organoids- or non-biological particles are dispersed in a hydrogel precursor and loaded in the SIM carrier. A vertical vibration generated with sound is applied, and a pattern is generated within seconds. Crosslinking of the patterned particulates within the hydrogel is carried out by using different stimuli (light, enzymatic, thermal crosslinking) ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
ZAVA is a chemically defined, synthetic hydrogel that allows you to exploit the full potential of SIM – long term patterning, gelation upon demand, and biologically active sites. The hydrogel is photosensitive and crosslinks upon irradiation at 405 nm. MMP-cleavable sites and RGD peptides allow for potential cell spreading and migration and promote cell adhesion. ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
KYTO is a chemically defined, synthetic hydrogel that bears biologically active sites. An MMP-cleavable crosslinker allows for potential cell spreading and migration. The hydrogel can be customised to bear a cell adhesive peptide, RGD, to further fine-tune the properties for specific applications. KYTO increases in viscosity after 8 to 10 minutes, enabling a dense and well-defined cell pattern to ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
LUMPO is a chemically defined, synthetic hydrogel that crosslinks upon irradiation at 405 nm. This hydrogel does not bear any biologically active sites. The viscosity has been optimised to allow for prolonged patterning of single cells or particles. Gelation on demand is ideal to exploit the method of sound induced morphogenesis. ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
BAKU is a chemically defined, synthetic hydrogel based on Dextran and PEG. This hydrogel does not bear any biologically active sites. Viscosity and gelation kinetics were adapted to allow for patterning of individual cells or particles. ...
Manufactured by:MV BioTherapeutics SA based inBellinzona, SWITZERLAND
The ApyraVax technology exploits the live attenuated typhoid vaccine as vector to deliver orally an enzyme that breaks down ATP (apyrase) together with desired antigen/s. The innovative feature is the unique ability to generate high-affinity secretory IgA that are protective towards the target infectious ...
Manufactured by:MV BioTherapeutics SA based inBellinzona, SWITZERLAND
MV010/MV004, in cancer immunotherapy • Significant increase of tumor specific cytotoxic T cells infiltrating the tumor microenvironment by combining MV010/MV004 to anti-PD-L1 administration in murine models. • Significantly improved tumor eradication and resistance to subsequent grafting and improved survival in murine models. ...
Manufactured by:MV BioTherapeutics SA based inBellinzona, SWITZERLAND
SNP-apyrase for oral use in the treatment of IBD • Lead compound, MV010, has shown animal PoC in a murine model of ulcerative colitis. • Abrogation of the pro-inflammatory function of extracellular ATP in the intestine without systemic immune suppression. • Amplification of secretory IgA production in Peyer's patches and gut-associated lymphoid tissue (GALT), ensuring high specificity for ...
Manufactured by:Thermo Fisher Scientific based inWaltham, MASSACHUSETTS (USA)
MAM has been broadly embraced by the biotherapeutic industry and regulatory leaders in recent years. Major biopharmaceutical companies are making significant investments to establish a MAM workflow to future proof the development and manufacturing of their biotherapeutics. Historically, the implementation of MAM has not been easy or fast due to the absence of a ...