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Solid Tumor Equipment Supplied In United Kingdom
18 equipment items found
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M4 (MAGE-A4) SPEAR T-cell therapy is directed to a member of the MAGE family of cancer testis antigen expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer-testis antigens. We are conducting various trials with the ADP-A2M4 SPEAR T-cell in various solid ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M4CD8 SPEAR T-cell therapy is our first "next-generation" therapy and is directed to MAGE-A4, a member of the MAGE family of cancer-testis antigens expressed in a number of solid tumor types. What differentiates this therapy from our ADP-A2M4 SPEAR T-cells is that these cells also express the CD8α co-receptor alongside the engineered TCR that ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M10 (MAGE-A10) T-cell therapy is directed to a member of the MAGE family of cancer testis antigens expressed in a number of solid tumor cell types. Any expression in cancer is often associated with higher grade tumors. Please note that the two trials with ADP-A2M10 are now closed for ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
It is a human monoclonal antibody that can be potentially used in the treatment of Hepatocellular Carcinoma, Gestational Trophoblastic Neoplasia, Choriocarcinoma, Placental Site Trophoblastic Tumor, Epithelioid Trophoblastic Tumor, Adult Solid Tumor, Advanced Soft Tissue Sarcoma, Metastatic Breast Cancer, Solid ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TCB005 is an allogeneic CAR-T product which targets B7-H3 (also known as CD276). B7-H3 expression has been detected in a wide range of solid tumors including lung, breast, colorectal, liver and skin cancers. It has also been observed on tumor vasculature and stroma, has been hypothesized to be an immune checkpoint and to be expressed on cancer ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
These T cell banks provide TC BioPharm with core technology to develop a deep portfolio of next-generation CAR-T products directed against a wide variety of different infectious diseases such as SARS-CoV-2 and cancer types, both hematological and solid tumors. Our cell bank project is supported by funding from the European Union’s Horizon 2020 (H2020) ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TCB006 is an allogeneic CAR-T product targeting B7-H4 for the treatment of cancers arising from solid tumors. B7-H4 antigen is overexpressed in breast cancers, especially triple negative breast cancer, and ovarian cancers, both diseases with acute clinical needs. There are 270,000 new cases of breast cancer and 23,000 new cases of ovarian cancer per year ...
Manufactured by:Oxford Gene Technology IP Limited based inOxford, UNITED KINGDOM
The HER2 amplification probe consists of a 347kb probe labelled in red, spanning the HER2 (ERBB2) gene and neighbouring regions, and a green probe for the chromosome 17 ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
SCIB2 is the second cancer vaccine based on the ImmunoBody® technology and encodes a modified antibody engineered to express the cancer antigen NY-ESO-1. This is a well-characterised and validated cancer target, being overexpressed in several tumour types including synovial sarcomas, oesophageal, liver, gastric, prostate and lung ...
Manufactured by:Biosceptre International Limited based inCambridge, UNITED KINGDOM
We are also developing antibodies that specifically target nfP2X7 for use in both solid and haematological tumours. Our preclinical data is very promising and studies show an excellent safety profile. By exploiting the modular nature of the antibody structure, the same panel of antibody sequences can be used to generate a variety of therapeutic antibody formats including, but not limited to, ...
Manufactured by:Datar Cancer Genetics based inGuildford, UNITED KINGDOM
Chemo-scale is an advanced non-invasive test which provides therapeutically relevant information and is based on a safe, simple, and quick blood draw. Chemo-scale™ investigates in vitro chemo-resistance in Circulating Tumor Associated Cells (CTACs) isolated from the blood sample. CTACs include cancer cells that escape from the tumor and enter the bloodstream (circulating tumor cells, CTCs) ...
Manufactured by:Datar Cancer Genetics based inGuildford, UNITED KINGDOM
Cancertrack is an advanced non-invasive blood test which provides real time intel on the status of a malignancy from a safe, simple and quick blood draw. Cancertrack profiles molecular features in circulating tumor DNA and circulating tumor RNA and also evaluates ‘Circulating Tumor Cells’ ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
Modi-1 is the first vaccine based on Scancell’s Moditope® platform. The vaccine is composed of a combination of three peptides from two target antigens that are commonly modified in cancer cells. The first is the cytoskeletal protein, vimentin, which is preferentially digested during autophagy. All mesenchymal tumours such as endometrial, renal, sarcomas, lymphomas and lung tumours ...
Manufactured by:Datar Cancer Genetics based inGuildford, UNITED KINGDOM
Trublood is an advanced non-invasive blood test (which provides diagnostically relevant information about cancers via a safe, simple and quick blood draw). Trublood® evaluates blood sample to detect ‘Circulating Tumor Cells’ (CTCs), which are cancer cells that escape from the tumor and enter the blood stream. Trublood® enriches these CTCs from the blood sample and confirms ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
Glycosylation is a post-translational modification that occurs inside the cell and results in the addition of sugar motifs, “glycans”, to proteins and lipids that are, in most cases, destined for the cell surface. These glycan structures form the “glycome” and play an integral role in cell-to-cell and cell-to-matrix interactions through modulation of adhesion and cell ...
Manufactured by:PsiOxus Therapeutics Ltd. based inAbingdon, UNITED KINGDOM
Our clinically validated T-SIGn® viral vector platform delivers multiple transgene payloads that re-program the tumor microenvironment of both primary and metastatic tumors. Our platform can integrate rationally designed synthetic agents to unleash the power of the immune system, including genetically engineered cell ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our goal is to revolutionize cancer therapy on a global basis by developing TCR T-cell therapies (called SPEAR T-cells) with the potential to treat a wide range of cancer types and patients. Our TCR T-cell therapies have advantages over other immune therapies and cancer therapies. The video below provides more ...
Manufactured by:Sartorius AG based inGoettingen, GERMANY
Innovation is at the heart of everything we do. Our proprietary drug delivery technology platform, Veltis®, uses engineered recombinant albumin to enhance albumin’s intrinsic characteristics for optimal therapeutic performance of your ...