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  • addex therapeutics
  • alkahest

G Protein Coupled Receptor Equipment Supplied In Usa California

3 equipment items found
In CaliforniaAvailable In CaliforniaNear California

Addex Therapeutics - Allosteric Modulators Technology

Addex Therapeutics - Allosteric Modulators Technology

Manufactured by:Addex Therapeutics   based inGeneva, SWITZERLAND
Allosteric modulators are an emerging class of orally available small molecule therapeutic agents that may offer a competitive advantage over classical ...
CONTACT SUPPLIER

Alkahest - Model AKST4290 - Targeting Eotaxin Cell

Alkahest - Model AKST4290 - Targeting Eotaxin Cell

Manufactured by:Alkahest, Inc.   based inSan Carlos, CALIFORNIA (USA)
One the key chronokine targets identified using Alkahest’s platform is eotaxin. Eotaxin is an immunomodulatory chemokine that is increased in normal aging as well as multiple diseases of aging. It has been implicated in Alzheimer’s disease, Parkinson’s disease, retinal diseases and other aging-related diseases that involve systemic inflammation, demonstrating effects both in the ...
CONTACT SUPPLIER

Model Encaleret - Ca Sensing Receptor Antagonist For Autosomal Dominant Hypocalcemia Type 1 (Adh1)

Model Encaleret - Ca Sensing Receptor Antagonist For Autosomal Dominant Hypocalcemia Type 1 (Adh1)

Manufactured by:BridgeBio Pharma, Inc.   based inPalo Alto, CALIFORNIA (USA)
Encaleret is an investigational small molecule antagonist of the calcium sensing receptor (CaSR) being studied in disorders of calcium homeostasis, including autosomal dominant hypocalcemia type 1 (ADH1). Individuals with ADH1 have gain-of-function mutations in the CaSR, causing low serum calcium and a range of debilitating symptoms. ADH1 may also lead to relatively high levels of calcium in ...
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