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Parkinsons Disease Equipment Supplied In Usa California
11 equipment items found
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
We are developing mGlu4 PAM as a novel orally available treatment for Parkinson's disease. We are currently optimizing multiple chemical series of highly selective mGlu4 PAMs with compounds in early lead ...
Manufactured by:AnaSpec based inFremont, CALIFORNIA (USA)
Parkinson's disease is predominantly a movement disorder resulting from degeneration of dopaminergic neurons in the substantia nigra. The cause of the disease is unknown, but substantial evidence suggests that the aggregation of α-synuclein is a critical step in the etiology of Parkinson's disease (PD). ...
Manufactured by:Kaneka Eurogentec S.A. based inSeraing, BELGIUM
α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly expressed in brain, specifically in ...
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
Dipraglurant is a novel orally available highly selective metabotropic glutamate receptor subtype 5 negative allosteric modulator (mGlu5 NAM) which has completed Phase 1 and demonstrated efficacy in a Phase 2a proof of concept study for the treatment of levodopa-induced dyskinesia associated with Parkinson’s disease (PD-LID). This is a ...
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
mGlu2 NAM for the treatment of mild neurocognitive disorders, or mNCD. We are developing mGlu2 NAM as a novel orally available treatment for mNCD associated with Alzheimer’s disease, Parkinson’s disease and depressive disorders. The program is in clinical candidate selection phase and we expect to enter IND enabling studies early in ...
Manufactured by:Aviva Systems Biology Corporation based inSan Diego, CALIFORNIA (USA)
25 ugof the indicated Human whole cell extracts was loaded onto a 12%SDS-PAGEgel. 3 ug/mL of the antibody was used in this ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
Alkahest, with its partner Grifols, is developing lead clinical candidates, GRF6019 and GRF6021, as potential treatments for neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease with cognitive impairment. Designed to safely replenish regenerative positive chronokines that decrease with age, ...
Manufactured by:Vala Sciences based inSan Diego, CALIFORNIA (USA)
By maintaining brain homeostasis, clearing cellular debris [3], pruning synapses [4], and eliminating protein aggregates [5], microglia play key roles in neurodevelopment [6], Alzheimer’s Disease [7], Parkinson’s Disease [8], ALS [9], traumatic brain injury [10], and many other central nervous system ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
One the key chronokine targets identified using Alkahest’s platform is eotaxin. Eotaxin is an immunomodulatory chemokine that is increased in normal aging as well as multiple diseases of aging. It has been implicated in Alzheimer’s disease, Parkinson’s disease, retinal diseases and other ...
Manufactured by:Advanced Brain Monitoring, Inc. based inCarlsbad, CALIFORNIA (USA)
Sleep Profiler™ EEG Sleep Monitor bridges the gap between laboratory polysomnography and actigraphy. Three frontopolar channels provide the EEG, EOG and EMG signal features needed to characterize by-stage sleep time. The lightweight, wireless device includes voice messages and other intuitive design features that enable reliable self-application in the home with acquisition across multiple ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
They have been implicated in many human neurodegenerative disorders such as multiple sclerosis, amyotrophic lateral sclerosis (ALS), Alzheimer’s disorder, Huntington’s disease and Parkinson’s disease. Tempo’s iAstro™: human iPSC-derived astrocytes are derived from integration-free induced pluripotent stem cell (iPSC) ...