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Tumor Cells Equipment Supplied In Usa California
86 equipment items found
Manufactured by:Fate Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
MICA and MICB (MICA/B) are stress proteins expressed on a broad range of solid and hematopoietic tumor cells and serve as an activation signal for NKG2D+ NK and T cells. However, MICA/B are frequently shed as an immune escape mechanism, preventing recognition and destruction of tumor cells by the immune system. ...
Manufactured by:Stanford Chemicals Company based inLake Forest, CALIFORNIA (USA)
It is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of 2019-nCoV (COVID-19) infection in ...
Manufactured by:T-Cure BioScience, Inc. based inSherman Oaks, CALIFORNIA (USA)
T cell engineering with TCRs is a growing area of immuno-oncology with recent breakthroughs in clinical settings. The T-Cure approach involves identifying and isolating a high avidity TCR which specifically recognizes an intracellular or cell-surface target in solid tumors. This TCR is then typically introduced into a viral vector that can ...
Manufactured by:Novodiax, Inc. based inHayward, CALIFORNIA (USA)
The CD45 antigen is a protein which was originally called Leukocyte Common Antigen and recognizes an antigen found on lymphoid cells. Anti-CD45 antibody is a useful tool for identifying tumor cells of lymphoid ...
Manufactured by:CytomX Therapeutics, Inc. based inSouth San Francisco, CALIFORNIA (USA)
CytomX is developing CX-2009, a Probody drug conjugate (PDC) conjugated with DM4, a highly potent cytotoxic drug, targeting CD166, also known as ALCAM. CD166 is a molecule widely and highly expressed on solid tumor cells and previously considered “undruggable” given its expression on normal tissues. In preclinical studies, Probody drug conjugates ...
Manufactured by:Biocept based inSan Diego, CALIFORNIA (USA)
As healthy and diseased tissue interact with the bloodstream, they release both cellular and genetic material into the circulation. These materials are referred to as “cell-free” DNA (cfDNA), and circulating tumor cells (CTCs). Conventional blood collection tubes contain only anti-coagulants, designed to prevent blood clotting. Over ...
Manufactured by:Novodiax, Inc. based inHayward, CALIFORNIA (USA)
The CD45 antigen is a protein which was originally called Leukocyte Common Antigen and recognizes an antigen found on lymphoid cells. Anti-CD45 antibody is a useful tool for identifying tumor cells of lymphoid origin. It is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by ...
Manufactured by:CytomX Therapeutics, Inc. based inSouth San Francisco, CALIFORNIA (USA)
CytomX and AbbVie are co-developing CX-2029, a PDC directed against CD71, the transferrin receptor that is highly expressed on a number of solid and hematologic tumors, as well as many normal tissues. CytomX is evaluating CX-2029 in a Phase 1/2 clinical trial as monotherapy. CD71 is an excellent “internalizer,” which has the potential to efficiently deliver toxin to ...
Manufactured by:Galvanize Therapeutics, Inc. based inRedwood City, CALIFORNIA (USA)
The Aliya PEF System is an advanced medical device used primarily for the surgical ablation of soft tissues, delivering high voltage, short-duration electrical energy to target cells. The system employs pulsed electric field technology to disrupt cellular homeostasis, leading to non-thermal programmed cell death while maintaining the integrity of the surrounding ...
Manufactured by:Ibio, Inc. based inBryan, TEXAS (USA)
Advances in the field of immuno-oncology have led to new and better treatment outcomes for a range of cancers, and particularly, blood cancers. However, even with the advent of checkpoint inhibitors as immunotherapies for solid tumors, significant challenges remain. This is in part due to dynamics in the tumor microenvironment, wherein regulatory T ...
Manufactured by:Qualigen Therapeutics, Inc. based inCarlsbad, CALIFORNIA (USA)
QN-247, formerly referred to as ALAN (Aptamer Linked Anti Nucleolin), is an aptamer-based investigational drug candidate currently under development and evaluation with the potential to treat a variety of different cancer types, including liquid and solid tumors. A key component of this drug candidate, the QN-165 aptamer, has been tested in over 100 cancer patients and is well ...
Manufactured by:Filtricine, Inc. based inSanta Clara, CALIFORNIA (USA)
Filtricine’s Innovative Technology Restricts Nutritional Support to Cancer Cells. Our strategy is to eliminate cancer cells’ access to non-essential amino acids, which the cancer cells require for growth. Our first technology is used in the development of exclusive replacement meals that can cut off the supply of target nutrients to cancer cells when consumed as the sole source of ...
Manufactured by:Filtricine, Inc. based inSanta Clara, CALIFORNIA (USA)
The hyperactive metabolism of cancer cells is extensively modified to support their unsustainable consumption of nutrients, which is what allows cancer cells to reproduce rapidly. Yet cancer cells lose their ability to make certain nutrients on their own like healthy cells do. Instead, cancer cells must obtain these nutrients from the bloodstream and from body fluid. Our laboratory experiments ...
Manufactured by:InnoPep Inc. based inSan Diego, CALIFORNIA (USA)
Programed cell death protein 1 (PD-1) is a cell surface receptor. PD-1 and its ligand PD-L1 are crucial immune checkpoints to downregulate T cell activation, tolerance and immunopathology. Several types of cancer cells overexpress PD-L1 in order to escape from the PD-1/PD-L1 immunosurveillance mechanism. Human PD-L1 inhibitor II is a peptide-based molecule. It binds to human PD-1 and inhibits ...
Manufactured by:Kaneka Eurogentec S.A. based inSeraing, BELGIUM
Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell ...
Manufactured by:Aelan Cell Technologies based inSan Francisco, CALIFORNIA (USA)
Cancer survival rates decrease with age, in part because the efficacy of cancer therapies decline for older ...
Manufactured by:ARRC LED based inSan Clemente, CALIFORNIA (USA)
Alternative modalities like Rife, Radio Frequency, PEMF, and TENS use electronic pulsing to create frequency resonance within the living cell. ATP RF (patent pending), Is an LED Therapy Bed that is an experimental Medical Device. Our mission is to create biological frequency resonance whereby the external vibration delivered via photons matches and amplifies the precise vibration of the target ...
Manufactured by:Brooklyn ImmunoTherapeutics (BTX) based inSan Diego, CALIFORNIA (USA)
Utilizing highly efficient mRNA-based gene editing, Brooklyn will precisely engineer changes in the genome of iPSC, followed by a thorough characterization of the new cell line. The gene-edited iPSC will then be used to produce iMSC that have been endowed with beneficial properties to broaden and enhance therapeutic uses. Our first gene-edited iMSC product will be used as a ...
Manufactured by:Senti Biosciences based inSouth San Francisco, CALIFORNIA (USA)
Pursuing an Unmet Need in the Treatment of CRC - SENTI-401 is designed to more precisely target and eliminate colorectal cancer (CRC) cells while sparing healthy cells elsewhere in the body. Our vision is a potential medicine that more effectively treats patients with colorectal ...
Manufactured by:Nkarta, Inc. based inSouth San Francisco, CALIFORNIA (USA)
OX40 costimulatory domain, CD3ζ signaling moiety, membrane bound ...