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Breast Cancer With Adjacent Normal Breast Equipment Supplied In Usa Massachusetts
8 equipment items found
Manufactured by:AMS Biotechnology (Europe) Ltd. based inAbingdon, UNITED KINGDOM
Breast cancer with adjacent normal breast tissue array (2012 WHO classification), including pathology grade, TNM and clinical stage (AJCC 7th edition), 12 cases/24 cores, repalcing BR245. Breast carcinoma with adjacent normal breast tissue ...
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
DSP-0390 is an emopamil-binding protein (EBP) inhibitor. EBP is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis.47 When functional, EBP mediates de novo cholesterol synthesis for cell membrane structure and signaling, enabling aberrant growth of tumors.47-50 Inhibition of EBP causes an accumulation of its substrates zymostenol and zymosterol, which contributes to ...
by:Psychē Systems Corporation based inHopkinton, MASSACHUSETTS (USA)
No two people’s bodies are exactly the same, so it stands to reason that people will react to medicines and treatments in different ways. While medical treatments can have broad, overall positive results, those results become varied when you examine the results in individual people and even in specific populations. That’s where precision medicine comes in. Precision medicine is the ...
Manufactured by:LifeSpan BioSciences, Inc based inShirley, MASSACHUSETTS (USA)
LTB4R2 is a low-affinity receptor for leukotrienes including leukotriene B4. It mediates the chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. LTB4R2 has been found to be overexpressed in esophageal ...
Manufactured by:Hologic, Inc. based inMarlborough, MASSACHUSETTS (USA)
A better 3D™ breast screening experience – for everyone. The new 3Dimensions™ system is designed to provide higher quality 3D™ images for radiologists, a more comfortable mammography experience for patients and enhanced workflow for technologists. Discover how sharper images and smarter technologies continue to help find invasive cancers – regardless of age or breast ...
Manufactured by:Cellanyx, LLC based inBeverly, MASSACHUSETTS (USA)
Risk stratification of early-stage breast cancer is an active area of research and several commercially available products that are based on genotypic classification. A vexing issue in breast cancer is carcinoma in situ – which has no metastatic potential. There are two sub types – Ductal Carcinoma in Situ (DCIS) and Lobular Carcinoma in Situ (LCIS). The incidence of these entities is ...
Manufactured by:Mersana Therapeutics based inCambridge, MASSACHUSETTS (USA)
ADCs are not one-size-fits-all. The Dolasynthen platform enables an iterative approach to develop the right ADC for a given indication through customization and optimization. Dolasynthen utilizes a synthetic scaffold for precise control of DAR (from 2-24) and site-specific antibody bioconjugation. The platform is also able to homogeneously generate ADCs with precisely defined DARs for consistent ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
Poor Solubility and Associated Formulation and Bioavailability Difficulties. Although paclitaxel is an effective anticancer drug, its solubility is low (~ 0.4 µg/mL), which limits its medical utility to intravenous applications. Docetaxel (Taxotere®) was developed as a paclitaxel derivative having improved water solubility; its solubility, however, is only ~ 14 µg/mL. Several ...