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Cytokine Equipment Supplied In Usa Massachusetts
17 equipment items found
Manufactured by:Transgene based inIllkirch-Graffenstaden, FRANCE
Two specific “weapons” have been integrated into the Vaccinia viral DNA: an anti-CTLA4 antibody, which was developed by BioInvent, and the cytokine GM-CSF, which triggers the body’s immune ...
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
DSP-0509 is an investigational Toll-like receptor (TLR) 7 agonist, which is hypothesized to induce cytokine production, activate cytotoxic T lymphocytes, and sustain immune-mediated antitumor ...
Manufactured by:Boston Pharmaceuticals based inCambridge, MASSACHUSETTS (USA)
BOS-475 is a selective BET (bromodomain and extra terminal) inhibitor. BOS-475 potently inhibits multiple clinically validated pathways (IL-12/IL-23-p40, Th17 cytokines and TNF) relevant to psoriasis pathophysiology. BOS-475 demonstrates broad inhibitory activities on other key disease-relevant immune-inflammatory mediators such as MCP-1, IL-6, and CXCL10 & 11. Topical ...
Manufactured by:JPT Peptide Technologies GmbH based inBerlin, GERMANY
PepSup is a highly standardized, peptide-based cell activation (cell stimulation) assay designed to produce short-term culture supernatants for analysis of cytokines or other mediators of interest. We create your PepSup Cell Activation Kit with your choice of PepMix Peptide Pools Antigen Peptides or custom peptides using a specialized culture medium. A PepSup kit contains ...
Manufactured by:AVEO Pharmaceuticals, Inc. based inBoston, MASSACHUSETTS (USA)
AV-380 is AVEO’s first-in-class, potent, humanized inhibitory IgG1 antibody targeting growth differentiation factor 15 (GDF15). GDF15 is a pro-inflammatory cytokine whose elevated circulating levels have been correlated with cachexia in cachectic cancer patients and several animal models of cancer cachexia. Current evidence suggests that a pro-inflammatory state may be ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
Adjuvants can improve the performance of vaccines by targeting the antigen to antigen-presenting cells, eliciting specific cytokines that direct Th1 or Th2 immune responses. Most of the adjuvants increase the production of specific antibodies. Adjuvants that enhance cell-mediated immunity for vaccines against bioterrorist agents are desirable since many of these agents are ...
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Our proprietary cytoDRiVE® platform leverages drug responsive domains (DRDs) to control protein function using an FDA-approved small ...
Manufactured by:TargetMol Chemicals Inc. based inWellesley Hills, MASSACHUSETTS (USA)
GLPG3312 is a selective and potent pan-SIK inhibitor with the advantage of oral activity, with IC50=0.6-2.0 nM for SIK1, SIK2 and SIK3, and exhibits anti-inflammatory and immunomodulatory activity in both human primary myeloid cells and mouse ...
Manufactured by:Isto Biologics based inHopkinton, MASSACHUSETTS (USA)
Inforce™ is a line of flexible, lightweight, dehydrated amniotic membrane sheets. Acting as a protective barrier to aid in wound management, Inforce™ provides scaffold, growth factors, and is ...
Manufactured by:Boston Pharmaceuticals based inCambridge, MASSACHUSETTS (USA)
BOS-421 is a highly selective, brain penetrant RIPK1 ...
Manufactured by:TargetMol Chemicals Inc. based inWellesley Hills, MASSACHUSETTS (USA)
RMC-9805 is a novel, mutant-selective, covalent and oral KRASG12D (ON) inhibitor. A stable and high affinity triple complex is formed between RMC-9805, KRASG12D, and cyclophilin A, which inhibits signal transduction downstream of KRASG12D (ON) by disrupting its interaction with downstream effectors. RMC-9805 can induce cell apoptosis and promote tumor regression in preclinical KRASG12D tumor ...
Manufactured by:Bruker Corporation based inBillerica, MASSACHUSETTS (USA)
Optofluidic Technology is the Key to Faster Workflows and Deeper Data. See how opto-electropositioning (OEP) technology moves Cell Biology to light speed. Our technology combines precise cell processing, time-saving workflow automation, and rich, deep profiling. Watch this video animation, to see how Berkeley Lights advanced technology works. Welcome to the ...
Manufactured by:Mersana Therapeutics based inCambridge, MASSACHUSETTS (USA)
Immunosynthen is our novel immunostimulatory ADC platform designed to take ADCs beyond traditional cytotoxic drugs to targeted stimulation of the innate immune system. Through the safe and efficient delivery of a novel immunomodulatory STING agonist, ADCs created with our Immunosynthen platform have the potential to address the challenges of efficacy, delivery and tolerability. Stimulator of ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Research mechanisms of neuroinflammation and evaluate the effect of therapeutics in a comprehensive model of the neurovascular ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Investigate mechanisms of colon inflammation and barrier disruption and evaluate the efficacy of anti-inflammatory drug candidates in an organoid-derived ...
Manufactured by:AOBiome Therapeutic, LLC based inCambridge, MASSACHUSETTS (USA)
The human microbiome consists of hundreds of trillions of microorganisms, outnumbering human cells by 10 to 1 with as many as 3 million bacterial genes to our approximately 20 thousand. While the microbiome has recently become an area of active research, its overall effects on human health remain largely ...
Manufactured by:BlueRock Therapeutics based inCambridge, MASSACHUSETTS (USA)
With our cell+gene platform, BlueRock is aiming to redefine the very way we treat disease, moving from addressing mere symptoms to restoring health lost to cell damage or degeneration. Instead of prescribing a pill to treat tremors in patients with Parkinson’s, we might restore the chemical messengers that were destroyed, addressing tremors at the source. Those who have suffered a heart ...