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In Vitro Comparative Studies Equipment Supplied In Usa Massachusetts
4 equipment items found
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
TP-0184 is an investigational inhibitor of activin receptor-like kinase 2 (ALK2) and ALK5 (also known as TGFβR1). This bimodal inhibitor is believed to downregulate multiple TGF-β superfamily signaling pathways and has shown antitumor activity in several ...
Manufactured by:CELLINK based inBoston, MASSACHUSETTS (USA)
CELLINK® PCL is a high-molecular weight (Mn 50,000) thermoplastic linear polyester derived from caprolactone monomer. This biodegradable polyester has a melting point of 60° C. PCL provides a reinforcing structure to load-bearing tissue constructs, including bone grafts and osteochondral plugs developed for in vitro and in vivo studies. It can also provide a temporary scaffold for ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
A combination therapy consisting of PKC agonists with or without HDAC inhibitors, designed to reactivate latent HIV reservoirs so that HIV can be eliminated by antiviral therapy and eradicated from the body. HIV Latency: Although highly active antiretroviral therapy (HAART) is undoubtedly a lifesaving therapy for millions of AIDS patients, the persistence of latent HIV-infected cellular ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
An alpha (α)-secretase modulator for ameliorating Alzheimer’s Disease pathophysiology and cognitive impairment with neuroprotection. Aphios is developing APH-1104, a more potent analog of Bryostatin-1, which is neuroprotective by α-secretase activation via novel PKC isoforms, down-regulation of pro-inflammatory and angiogenic processes and the substitution of β-amyloid for ...