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Immune Response Equipment Supplied In Usa Pennsylvania

7 equipment items found
In PennsylvaniaAvailable In PennsylvaniaNear Pennsylvania

INOVIO - Model IN VIVO - DNA Medicines Technology

INOVIO - Model IN VIVO - DNA Medicines Technology

Manufactured by:INOVIO Pharmaceuticals   based inPlymouth Meeting, PENNSYLVANIA (USA)
Once inside the cell, the DNA plasmids enable the cell to produce the targeted antigen. The antigen is processed naturally in the cell and triggers the desired T cell and antibody-mediated immune response. Administration with the CELLECTRA device ensures that the DNA medicine is efficiently delivered directly into the body’s cells, where it can go to work ...
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Model FVIII-CAART - Discovery-Stage Candidate for Hemophilia

Model FVIII-CAART - Discovery-Stage Candidate for Hemophilia

Manufactured by:Cabaletta Bio, Inc.   based inPhiladelphia, PENNSYLVANIA (USA)
In addition to our work on autoimmune disease treatments, we are investigating the viability of CAART as an adjunct in cases where the immune system produces antibodies against current therapies (rather than against the patient’s cells). We believe our approach has the potential to destroy those antibodies by ablating B cells, similar to the method we have used to combat ...
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Adaptimmune - Model ADP-A2M4CD8 Spear - T-Cell Therapy Pipeline

Adaptimmune - Model ADP-A2M4CD8 Spear - T-Cell Therapy Pipeline

Manufactured by:Adaptimmune LLC   based inPhiladelphia, PENNSYLVANIA (USA)
What differentiates this therapy from our ADP-A2M4 SPEAR T-cells is that these cells also express the CD8α co-receptor alongside the engineered TCR that targets MAGE-A4. Preclinical data indicate that co-expression of CD8α may broaden the immune response against solid tumors and increase anti-tumor activity by leveraging CD4+ cells into CD8+ killer or ...
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Lava - Model Vy9Vd2 - Gamma-Delta T Cells

Lava - Model Vy9Vd2 - Gamma-Delta T Cells

Manufactured by:LAVA Therapeutics N.V.   based inUtrecht, NETHERLANDS
Vγ9Vδ2 T cells belong to the first line of defense against cancer and have the potential to elicit deep and durable responses in the ...
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Sino - Model CD89 - 10414-H08H - Human Recombinant Protein (ECD, His Tag)

Sino - Model CD89 - 10414-H08H - Human Recombinant Protein (ECD, His Tag)

Manufactured by:Sino Biological Inc.   based inWayne, PENNSYLVANIA (USA)
Purity:> 97 % as determined by SDS-PAGE. Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method. ...
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Sino - Model CD89 - 80014-R08H - Rat Recombinant Protein (His Tag)

Sino - Model CD89 - 80014-R08H - Rat Recombinant Protein (His Tag)

Manufactured by:Sino Biological Inc.   based inWayne, PENNSYLVANIA (USA)
FCAR, also called FcαRI or CD89, is a type I transmembrane receptor for Fc region of IgA which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. This receptor is present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, especially phagocytes located in mucosal ...
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BriaCell - Model Bria-IMT and Bria-OTS - Destroy Cancer Cells

BriaCell - Model Bria-IMT and Bria-OTS - Destroy Cancer Cells

Manufactured by:BriaCell Therapeutics Corp.   based inWest Vancouver, BRITISH COLUMBIA (CANADA)
The mechanism of action of Bria-IMT™/Bria-OTS™ is currently under investigation. We believe that Bria-IMT™/Bria-OTS™, activates the patient’s immune system to recognize tumor cells and destroy them. We hypothesize that Bria-IMT™/Bria-OTS™, exert their action by stimulating the antigen-presentation system (i.e. the system that presents antigen material on ...
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